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Hiromi Rakugi Selected Research

olmesartan

10/2015Preferable effects of olmesartan/calcium channel blocker to olmesartan/diuretic on blood pressure variability in very elderly hypertension: COLM study subanalysis.
1/2015Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial.
10/2014Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: a randomized, controlled trial.
11/2010Strong suppression of the renin-angiotensin system has a renal-protective effect in hypertensive patients: high-dose ARB with ACE inhibitor (Hawaii) study.
4/2010Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice.
12/2009Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling.
2/2009Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients.
7/2007Renin-angiotensin inhibition reverses advanced cardiac remodeling in aging spontaneously hypertensive rats.
2/2004Calcium channel blocker azelnidipine enhances vascular protective effects of AT1 receptor blocker olmesartan.

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Hiromi Rakugi Research Topics

Disease

53Hypertension (High Blood Pressure)
10/2015 - 07/2003
25Cardiovascular Diseases (Cardiovascular Disease)
10/2015 - 12/2004
22Kidney Diseases (Kidney Disease)
10/2015 - 01/2006
18Insulin Resistance
01/2015 - 01/2002
16Proteinuria
06/2015 - 07/2004
14Atherosclerosis
06/2013 - 04/2002
13Fibrosis (Cirrhosis)
11/2015 - 07/2007
10Inflammation
03/2015 - 10/2006
9Diabetes Mellitus
11/2013 - 11/2009
9Alzheimer Disease (Alzheimer's Disease)
01/2013 - 07/2009
8Body Weight (Weight, Body)
01/2015 - 06/2005
8Stroke (Strokes)
01/2015 - 07/2009
7Obesity
05/2011 - 09/2003
6Chronic Kidney Failure (Chronic Renal Failure)
10/2015 - 01/2010
5Osteoporosis
05/2014 - 05/2009
5Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
04/2013 - 12/2004
5Coronary Artery Disease (Coronary Atherosclerosis)
01/2013 - 04/2004
5IGA Glomerulonephritis (IGA Nephropathy)
11/2012 - 03/2010
5Peripheral Arterial Disease
06/2012 - 08/2005
5Dementia (Dementias)
01/2012 - 07/2009
4Hypertrophy
04/2015 - 04/2006
4Edema
01/2015 - 02/2012
4Fatty Liver
06/2014 - 01/2009
4Glomerulonephritis
01/2014 - 01/2011
4Hyperuricemia
01/2013 - 02/2008
4Hyperemia
12/2011 - 06/2002
4Cardiomegaly (Heart Hypertrophy)
07/2007 - 01/2002
3Ureteral Obstruction
11/2015 - 04/2006
3Hyperphosphatemia
10/2015 - 05/2012
3Tonsillitis
04/2015 - 03/2010
3Ischemia
03/2015 - 02/2012
3Pain (Aches)
03/2015 - 04/2010
3Heart Failure
01/2015 - 04/2006
3Bone Fractures (Bone Fracture)
05/2014 - 09/2009
3Hyperlipidemias (Hyperlipidemia)
01/2014 - 06/2005
3Albuminuria
01/2014 - 04/2010
3Glucose Intolerance
01/2013 - 06/2010
3Anemia
12/2012 - 08/2009
3Acute Kidney Injury (Acute Renal Failure)
02/2012 - 04/2009
3Diabetic Nephropathies (Diabetic Nephropathy)
02/2012 - 04/2010
3Secondary Hyperparathyroidism
06/2011 - 05/2009
3Hyperinsulinism (Hyperinsulinemia)
01/2009 - 01/2002
3Weight Gain
12/2006 - 06/2005
2Ulcer
03/2015 - 12/2011
2Parkinson Disease (Parkinson's Disease)
01/2015 - 10/2007
2Hyperglycemia
10/2014 - 09/2003

Drug/Important Bio-Agent (IBA)

16Angiotensin IIIBA
08/2015 - 06/2004
15Insulin (Novolin)FDA Link
04/2014 - 01/2002
14AngiotensinsIBA
01/2015 - 01/2002
12CreatinineIBA
12/2013 - 06/2005
9olmesartanIBA
10/2015 - 02/2004
8Amlodipine (Norvasc)FDA LinkGeneric
05/2015 - 01/2006
8Glucose (Dextrose)FDA LinkGeneric
01/2015 - 01/2009
8Amyloid (Amyloid Fibrils)IBA
01/2014 - 07/2009
8AdiponectinIBA
01/2013 - 09/2003
8Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2012 - 06/2005
7Calcium Channels (Calcium Channel)IBA
10/2015 - 02/2004
7CalciumIBA
01/2015 - 04/2005
7benidipineIBA
01/2014 - 04/2005
6Type 1 Angiotensin ReceptorIBA
08/2015 - 07/2004
6Losartan (Cozaar)FDA LinkGeneric
05/2015 - 07/2004
6Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
11/2013 - 12/2004
6ReninIBA
06/2013 - 01/2002
5candesartanIBA
06/2014 - 12/2007
5Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
04/2013 - 04/2004
5Antihypertensive Agents (Antihypertensives)IBA
04/2012 - 11/2009
4MagnesiumIBA
10/2015 - 05/2009
4Hydrochlorothiazide (Esidrix)FDA LinkGeneric
05/2015 - 01/2014
4Vitamin DFDA LinkGeneric
01/2015 - 08/2009
4Parathyroid Hormone (Parathormone)IBA
01/2015 - 06/2012
4Uric Acid (Urate)IBA
01/2013 - 02/2006
4valsartan (Vals)FDA Link
11/2010 - 07/2004
4LeptinIBA
06/2008 - 11/2005
3DNA (Deoxyribonucleic Acid)IBA
07/2015 - 12/2011
3DiureticsIBA
01/2015 - 06/2005
3CholesterolIBA
01/2014 - 02/2008
3Non-alcoholic Fatty Liver DiseaseIBA
01/2014 - 01/2009
3ApolipoproteinsIBA
01/2014 - 09/2009
3Angiotensin Receptors (Angiotensin II Receptor)IBA
11/2013 - 01/2006
3Messenger RNA (mRNA)IBA
09/2013 - 07/2007
3telmisartan (Micardis)FDA Link
07/2013 - 02/2012
3ErythropoietinFDA Link
04/2013 - 08/2009
3alpha-Fetoproteins (AFP)IBA
03/2013 - 05/2009
3PeptidesIBA
01/2013 - 06/2011
3CytokinesIBA
12/2012 - 08/2005
3Brain Natriuretic Peptide (Natrecor)FDA Link
10/2012 - 01/2010
3fibroblast growth factor 23IBA
10/2012 - 05/2012
3Calcium Channel Blockers (Blockers, Calcium Channel)IBA
01/2012 - 06/2005
3Adrenergic Receptors (Adrenergic Receptor)IBA
05/2011 - 06/2005
3Biological Markers (Surrogate Marker)IBA
10/2010 - 07/2009
3Lipoproteins (Lipoprotein)IBA
07/2010 - 10/2009
2hydroxide ionIBA
11/2015 - 04/2009
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
06/2015 - 09/2009
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2015 - 04/2010
2Idiopathic minimal change nephrotic syndromeIBA
01/2015 - 12/2013
2GlucocorticoidsIBA
10/2014 - 05/2014

Therapy/Procedure

5Renal Dialysis (Hemodialysis)
01/2014 - 07/2009
3Tonsillectomy
04/2015 - 03/2010
3Transplants (Transplant)
01/2013 - 12/2011
2Amputation
03/2015 - 12/2011