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Deborah M Proctor Selected Research

chromium hexavalent ion

8/2015Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats.
8/2015Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy.
1/2015Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water.
11/2014Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures.
5/2014A chronic oral reference dose for hexavalent chromium-induced intestinal cancer.
3/2014High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice.
6/2013Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water.
3/2013Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans.
10/2012Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: an in silico comparison with mutagenic and nonmutagenic carcinogens across tissues.
10/2012Hexavalent chromium reduction kinetics in rodent stomach contents.
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Deborah M Proctor Research Topics

Disease

17Neoplasms (Cancer)
08/2015 - 05/2002
7Hyperplasia
08/2015 - 09/2011
2Intestinal Neoplasms (Intestinal Cancer)
08/2015 - 05/2014
2Lung Neoplasms (Lung Cancer)
11/2014 - 05/2002
1Anemia
03/2014
1Adenoma (Adenomas)
03/2013
1Carcinoma (Carcinomatosis)
03/2013
1Inflammation
01/2011
1Rectal Neoplasms (Rectal Cancer)
08/2010
1Esophageal Neoplasms (Esophageal Cancer)
08/2010
1Digestive System Neoplasms (Cancer of the Digestive System)
05/2002

Drug/Important Bio-Agent (IBA)

17chromium hexavalent ionIBA
08/2015 - 05/2002
3sodium bichromate (sodium dichromate)IBA
06/2013 - 01/2012
2DNA (Deoxyribonucleic Acid)IBA
01/2015 - 01/2011
1Codon (Codons)IBA
06/2013
1GATIBA
06/2013
1CarcinogensIBA
08/2007