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H Miles Prince Selected Research

romidepsin (FK228)

7/2015Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data.
1/2014Tolerability to romidepsin in patients with relapsed/refractory T-cell lymphoma.
1/2014Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable responses.
12/2013Romidepsin for cutaneous T-cell lymphoma.
8/2013Romidepsin for peripheral T-cell lymphoma.
10/2012A focus on the preclinical development and clinical status of the histone deacetylase inhibitor, romidepsin (depsipeptide, Istodax(®)).
7/2012Romidepsin for cutaneous T-cell lymphoma.
2/2012Results from a pivotal, open-label, phase II study of romidepsin in relapsed or refractory peripheral T-cell lymphoma after prior systemic therapy.
12/2011A high rate of durable responses with romidepsin, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma.
6/2011Phase 2 trial of romidepsin in patients with peripheral T-cell lymphoma.
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H Miles Prince Research Topics

Disease

25Multiple Myeloma
09/2015 - 07/2003
16Neoplasms (Cancer)
05/2015 - 07/2005
15Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
07/2015 - 10/2007
8Infection
02/2015 - 02/2003
8Lymphoma (Lymphomas)
01/2015 - 02/2004
7Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
07/2015 - 11/2009
6T-Cell Lymphoma (Lymphoma, T Cell)
07/2015 - 11/2009
4Mycosis Fungoides
01/2015 - 04/2010
4Hodgkin Disease (Hodgkin's Disease)
05/2014 - 01/2006
4Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
01/2014 - 04/2011
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2013 - 04/2005
4Neutropenia
02/2013 - 08/2004
3Lymphomatoid Papulosis
06/2015 - 05/2009
3Myelodysplastic Syndromes (Myelodysplastic Syndrome)
09/2013 - 08/2011
3Disease Progression
01/2013 - 07/2003
3Hematologic Neoplasms (Hematological Malignancy)
10/2012 - 12/2005
3Leukemia
07/2011 - 10/2007
3Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
02/2011 - 06/2006
2B-Cell Lymphoma (Lymphoma, B Cell)
02/2015 - 02/2004
2Stomatitis
08/2014 - 07/2005
2Central Nervous System Diseases (CNS Diseases)
12/2012 - 10/2009
2Thrombocytopenia (Thrombopenia)
03/2011 - 11/2007
2Waldenstrom Macroglobulinemia (Macroglobulinemia)
12/2010 - 09/2005
2Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell)
07/2010 - 03/2007
2Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2010 - 06/2006
2Melanoma (Melanoma, Malignant)
05/2009 - 10/2007
2Graft vs Host Disease (Graft-Versus-Host Disease)
10/2008 - 02/2008
2Peripheral Nervous System Diseases (PNS Diseases)
11/2006 - 09/2006
2Lymphoproliferative Disorders (Lymphoproliferative Disorder)
10/2006 - 08/2006
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2006 - 05/2004
1Angiodysplasia
01/2015
1Hemorrhage
01/2015
1Erdheim-Chester Disease
11/2014
1Histiocytosis
11/2014
1Mucositis
08/2014
1Contracture
09/2013
1Sepsis (Septicemia)
11/2012
1Amyloidosis
06/2012
1Myeloproliferative Disorders (Myeloproliferative Disorder)
05/2012
1Seroma
04/2012
1Psoriasis (Pustulosis Palmaris et Plantaris)
02/2012
1Rheumatic Diseases (Rheumatism)
02/2012
1Pneumonia (Pneumonitis)
10/2011
1Crohn Disease (Crohn's Disease)
02/2011

Drug/Important Bio-Agent (IBA)

15Histone Deacetylase InhibitorsIBA
01/2014 - 05/2007
12romidepsin (FK228)FDA Link
07/2015 - 11/2009
11Thalidomide (Thalomid)FDA Link
12/2012 - 07/2003
9rituximab (Mabthera)FDA Link
02/2014 - 02/2004
8bortezomib (Velcade)FDA Link
09/2015 - 08/2006
8LBH589IBA
05/2014 - 07/2008
7fludarabineIBA
12/2010 - 11/2004
6Dexamethasone (Maxidex)FDA LinkGeneric
09/2015 - 06/2005
5Melphalan (Alkeran)FDA LinkGeneric
08/2014 - 07/2005
5denileukin diftitox (Ontak)FDA Link
08/2013 - 05/2004
4lenalidomide (CC 5013)FDA Link
12/2012 - 10/2005
3Methotrexate (Mexate)FDA LinkGeneric
06/2015 - 10/2006
3CytokinesIBA
05/2014 - 12/2005
3AntigensIBA
11/2013 - 12/2005
3Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
06/2008 - 07/2006
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2006 - 11/2004
2Azacitidine (5 Azacytidine)FDA Link
09/2013 - 08/2011
2Carbon MonoxideIBA
09/2013 - 07/2005
2Histones (Histone)IBA
09/2013 - 06/2009
2PerforinIBA
04/2011 - 01/2008
2Interleukin-2 (IL2)IBA
04/2010 - 05/2004
2InterferonsIBA
04/2010 - 07/2003
2Mitoxantrone (Novantrone)FDA LinkGeneric
11/2006 - 11/2004
2alemtuzumab (Campath)FDA Link
12/2004 - 02/2003
1dasatinib (BMS 354825)FDA Link
01/2015
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2015
1Protein Kinases (Protein Kinase)IBA
11/2014
1Chemokine CCL17IBA
05/2014
1ChemokinesIBA
05/2014
1Antigen Receptors (Antigen Receptor)IBA
11/2013
1EnzymesIBA
09/2013
1CosmeticsIBA
09/2013
1Proteins (Proteins, Gene)IBA
08/2013
1collagen-related peptideIBA
06/2013
1Filgrastim (Neupogen)FDA Link
02/2013
1bexarotene (LGD1069)FDA Link
01/2013
1Anti-Bacterial Agents (Antibiotics)IBA
11/2012
1Immunoglobulins (Immunoglobulin)IBA
10/2011
1Intravenous Immunoglobulins (IVIG)FDA Link
10/2011
1Mucin-1 (CA 15-3 Antigen)IBA
04/2011
1Phosphotransferases (Kinase)IBA
04/2011
1LipopeptidesIBA
10/2010

Therapy/Procedure

17Drug Therapy (Chemotherapy)
01/2015 - 08/2002
9Stem Cell Transplantation
08/2014 - 12/2005
8Transplants (Transplant)
02/2015 - 04/2010
4Breast Implants (Breast Implant)
01/2014 - 04/2011
3Salvage Therapy
01/2015 - 09/2005
3Immunotherapy
10/2010 - 12/2006
2Ligation
05/2015 - 12/2005
2Aftercare (After-Treatment)
01/2015 - 08/2006
2Combination Drug Therapy (Combination Chemotherapy)
08/2006 - 11/2004
1Total Parenteral Nutrition
08/2014
1Analgesia
08/2014
1Retreatment
03/2013
1Blood Component Removal (Apheresis)
05/2012
1Hematopoietic Stem Cell Transplantation
01/2011