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Michael Platten Selected Research

nicotinate-nucleotide diphosphorylase (carboxylating)

6/2013The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.

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Michael Platten Research Topics

Disease

30Neoplasms (Cancer)
10/2015 - 12/2003
28Glioma (Gliomas)
10/2015 - 09/2003
17Glioblastoma (Glioblastoma Multiforme)
10/2015 - 12/2003
4Inflammation
07/2014 - 10/2007
4Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
09/2013 - 11/2005
3Astrocytoma (Pilocytic Astrocytoma)
12/2015 - 07/2012
3Multiple Sclerosis
12/2015 - 10/2003
3Autoimmune Diseases (Autoimmune Disease)
09/2011 - 11/2005
2Starvation
01/2015 - 10/2007
2Infection
01/2014 - 07/2012
2Neurodegenerative Diseases (Neurodegenerative Disease)
06/2013 - 10/2003
2Paralysis (Palsy)
08/2010 - 11/2005
1Hemorrhage
12/2015
1Ulcer
12/2015
1Leukopenia
12/2015
1Brain Neoplasms (Brain Tumor)
02/2015
1Melanoma (Melanoma, Malignant)
02/2015
1Colorectal Neoplasms (Colorectal Cancer)
01/2015
1Breast Neoplasms (Breast Cancer)
01/2015
1Mental Retardation (Idiocy)
01/2015
1alpha-Thalassemia
01/2015
1Adenoma (Adenomas)
10/2014
1Lung Neoplasms (Lung Cancer)
02/2014
1Anoxia (Hypoxia)
01/2014
1Hypersensitivity (Allergy)
01/2014
1Acquired Immunodeficiency Syndrome (AIDS)
01/2014
1Herpes Zoster
09/2013
1Huntington Disease (Huntington's Disease)
06/2013
1Thrombocytopenia (Thrombopenia)
07/2012
1Neutropenia
07/2012
1Lymphopenia (Lymphocytopenia)
07/2012

Drug/Important Bio-Agent (IBA)

9temozolomide (Temodar)FDA LinkGeneric
10/2015 - 08/2007
9Tryptophan (L-Tryptophan)FDA Link
01/2015 - 10/2007
8Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
02/2015 - 09/2010
5KynurenineIBA
01/2015 - 10/2007
4bevacizumabFDA Link
10/2015 - 03/2011
4DNA (Deoxyribonucleic Acid)IBA
01/2015 - 11/2005
4O(6)-Methylguanine-DNA MethyltransferaseIBA
07/2014 - 08/2013
3EnzymesIBA
12/2015 - 01/2014
3Biological Markers (Surrogate Marker)IBA
01/2015 - 08/2013
3Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
01/2015 - 10/2007
3Messenger RNA (mRNA)IBA
10/2014 - 09/2010
3Alkylating AgentsIBA
01/2014 - 02/2009
3Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
09/2012 - 10/2011
2AntigensIBA
08/2015 - 02/2015
2Small Interfering RNA (siRNA)IBA
01/2015 - 09/2011
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2015 - 12/2013
2O-(6)-methylguanineIBA
01/2015 - 08/2007
2AntibodiesIBA
08/2014 - 04/2014
2Transforming Growth Factors (Transforming Growth Factor)IBA
04/2014 - 11/2004
2Protein Kinases (Protein Kinase)IBA
01/2014 - 09/2013
2Histones (Histone)IBA
08/2013 - 01/2012
2Phosphotransferases (Kinase)IBA
01/2012 - 11/2004
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2011 - 01/2011
2Transforming Growth Factor beta (TGF-beta)IBA
08/2010 - 11/2004
1teriflunomideIBA
12/2015
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
10/2015
1tensins (tensin)IBA
10/2015
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
10/2015
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
10/2015
1Cancer VaccinesIBA
08/2015
1L 644711 (B-3(+))IBA
05/2015
1ParaffinIBA
02/2015
1Procarbazine (Matulane)FDA Link
01/2015
1Vincristine (Oncovin)FDA LinkGeneric
01/2015
1Tacrolimus (Prograf)FDA LinkGeneric
01/2015
1tacrolimus binding protein 4 (FKBP52)IBA
01/2015
1Lomustine (CCNU)FDA Link
01/2015
1Transcription Factors (Transcription Factor)IBA
01/2015
1Tryptophan Oxygenase (Tryptophan 2,3 Dioxygenase)IBA
01/2015
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2015
1Fas Ligand Protein (Fas Ligand)IBA
12/2014
1Drug CombinationsIBA
10/2014
1Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
10/2014
1nestin (nestin protein)IBA
10/2014
1Glial Fibrillary Acidic ProteinIBA
10/2014
1cytotoxic T-lymphocyte antigen 4IBA
04/2014
1cytochrome P-450 CYP1B1 (CYP1B1)IBA
02/2014
1Interleukin-6 (Interleukin 6)IBA
02/2014
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2014
1MethyltransferasesIBA
01/2014
1Methadone (Dolophine)FDA LinkGeneric
01/2014
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
12/2013
1enzastaurinIBA
10/2013
1claudin 3IBA
09/2013
1bisindolylmaleimideIBA
09/2013
1Carbon MonoxideIBA
09/2013
1PeroxiredoxinsIBA
08/2013
1CytosineIBA
08/2013
1GuanineIBA
08/2013
1Quinolinic AcidIBA
06/2013
1NAD (NADH)IBA
06/2013
1nicotinate-nucleotide diphosphorylase (carboxylating)IBA
06/2013
1N-Methylaspartate (NMDA)IBA
06/2013
1DioxygenasesIBA
09/2012

Therapy/Procedure

8Drug Therapy (Chemotherapy)
01/2015 - 08/2007
7Radiotherapy
12/2015 - 12/2008
6Immunotherapy
08/2015 - 12/2003
1Ligation
02/2015
1Salvage Therapy
03/2014