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Daniele Piomelli Selected Research

palmidrol

8/2015A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation.
1/2014Effects of acute stress on cardiac endocannabinoids, lipogenesis, and inflammation in rats.
4/2011Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages.
12/2009Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.
6/2009Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia.
7/2008Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury.
9/2007Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice.
8/2005The search for the palmitoylethanolamide receptor.
1/2005The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.
8/2002Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study.

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Daniele Piomelli Research Topics

Disease

36Pain (Aches)
08/2015 - 01/2004
24Inflammation
12/2015 - 01/2005
10Hyperalgesia
09/2015 - 02/2006
9Body Weight (Weight, Body)
09/2012 - 09/2003
7Obesity
09/2015 - 07/2004
6Alzheimer Disease (Alzheimer's Disease)
03/2013 - 01/2010
5Substance-Related Disorders (Drug Abuse)
02/2015 - 01/2004
4Neuralgia (Stump Neuralgia)
04/2009 - 02/2006
3Schizophrenia (Dementia Praecox)
04/2009 - 11/2004
3Marijuana Abuse (Cannabis Abuse)
01/2009 - 12/2002
2Breast Neoplasms (Breast Cancer)
09/2014 - 10/2011
2Heart Failure
01/2014 - 02/2006
2Neoplasms (Cancer)
01/2013 - 09/2012
2Amnesia (Dissociative Amnesia)
01/2013 - 01/2012
2Ischemia
10/2012 - 08/2002
2Dementia (Dementias)
08/2012 - 11/2004
2Tobacco Use Disorder (Nicotine Dependence)
01/2011 - 11/2008
2Shock
01/2011 - 03/2006
2Hypersensitivity (Allergy)
01/2010 - 04/2009
2Alcoholism (Alcohol Abuse)
07/2008 - 07/2007
2Nausea
02/2008 - 02/2007
2Edema
09/2007 - 01/2005
2Hypothermia
01/2006 - 08/2002
2Hyperphagia
01/2006 - 11/2002
2Dyskinesias (Dyskinesia)
08/2005 - 09/2003
1Pneumonia (Pneumonitis)
09/2015
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2015
1Wounds and Injuries (Trauma)
10/2014
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
03/2014
1Frontotemporal Dementia
03/2014
1Osteitis Deformans (Paget's Disease of Bone)
03/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
03/2014
1Muscular Diseases (Myopathy)
03/2014
1Overweight
07/2013

Drug/Important Bio-Agent (IBA)

23Endocannabinoids (Endocannabinoid)IBA
06/2015 - 08/2003
20anandamide (arachidonylethanolamide)IBA
06/2015 - 08/2002
12PPAR alphaIBA
12/2009 - 09/2003
11Cannabinoid Receptors (Cannabinoid Receptor)IBA
10/2014 - 12/2002
10palmidrolIBA
08/2015 - 08/2002
8fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
07/2015 - 09/2005
8cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester (URB597)IBA
01/2011 - 02/2006
7oleoylethanolamideIBA
08/2015 - 11/2002
7CarrageenanIBA
07/2015 - 01/2005
5amidaseIBA
08/2015 - 12/2009
4N-acylethanolaminesIBA
08/2015 - 12/2009
4CB1 Cannabinoid Receptor (CB1 Receptor)IBA
10/2014 - 09/2003
3Peroxisome Proliferator-Activated Receptors (PPAR)IBA
08/2015 - 04/2009
3Formaldehyde (Formol)FDA Link
02/2014 - 12/2006
3Memantine (Namenda)FDA Link
03/2013 - 01/2012
3GW 7647IBA
09/2012 - 12/2006
3URB937IBA
05/2012 - 10/2010
3Ethanolamine (Colamine)IBA
07/2008 - 01/2005
3Palmitic Acid (Hexadecanoic Acid)IBA
07/2008 - 01/2005
3OleylethanolamideIBA
02/2006 - 08/2002
2CeramidesIBA
12/2015 - 01/2015
2Fatty Acids (Saturated Fatty Acids)IBA
07/2015 - 09/2012
2EnzymesIBA
08/2014 - 10/2012
2Stearoyl-CoA DesaturaseIBA
01/2014 - 01/2011
2Neurotransmitter Agents (Neurotransmitter)IBA
01/2014 - 08/2007
2Triglycerides (Triacylglycerol)IBA
01/2014 - 07/2004
2GW 6471IBA
03/2013 - 09/2012
2Scopolamine (Hyoscine)FDA Link
01/2013 - 01/2012
2Amyloid (Amyloid Fibrils)IBA
01/2013 - 08/2012
2Galantamine (Galanthamine)FDA LinkGeneric
11/2012 - 01/2012
22-arachidonylglycerol (2-arachidonoylglycerol)IBA
10/2012 - 09/2003
2Lipase (Acid Lipase)FDA Link
10/2012 - 08/2011
2URB602IBA
10/2012 - 08/2011
2rimonabantIBA
09/2012 - 08/2005
2Freund's AdjuvantIBA
05/2012 - 12/2006
2NicotineFDA Link
01/2011 - 11/2008
2NF-kappa B (NF-kB)IBA
06/2009 - 09/2007
2LithiumIBA
02/2008 - 02/2007
2Levodopa (L Dopa)FDA LinkGeneric
08/2005 - 09/2003
1Peptide Hormones (Polypeptide Hormones)IBA
09/2015
1Streptozocin (Streptozotocin)FDA Link
07/2015
1Epoxide HydrolasesIBA
07/2015
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
06/2015
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
06/2015
1AM 251 (AM251)IBA
06/2015
11-dodecylpyridoxal (PLD)IBA
03/2015
1harpin (messenger)IBA
01/2015
1Methamphetamine (Desoxyn)FDA LinkGeneric
01/2015
1EstersIBA
12/2014
1Lipid AIBA
11/2014
1P-GlycoproteinIBA
09/2014
1Adenosine Triphosphate (ATP)IBA
09/2014
1CDC48 proteinIBA
03/2014
1LipidsIBA
03/2014
1Troponin IIBA
01/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2014
1Brain Natriuretic Peptide (Natrecor)FDA Link
01/2014
1Thiobarbituric Acid Reactive SubstancesIBA
01/2014
1Glycerol (Glycerine)FDA LinkGeneric
01/2014
1InterleukinsIBA
01/2014
1Biological Markers (Surrogate Marker)IBA
01/2014
1Dietary Fats (Ghee)IBA
07/2013

Therapy/Procedure

3Topical Administration
09/2015 - 03/2013
3Ligation
03/2013 - 02/2006
2Oral Administration
06/2015 - 07/2007
2Drug Therapy (Chemotherapy)
10/2014 - 02/2008