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Eng Eong Ooi Selected Research

MDL 28574

8/2014Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.
10/2012Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.
12/2011Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model.

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Eng Eong Ooi Research Topics

Disease

33Infection
11/2015 - 03/2004
25Dengue (Dengue Fever)
12/2015 - 08/2005
7Human Influenza (Influenza)
01/2015 - 01/2006
4Severe Acute Respiratory Syndrome
02/2006 - 03/2004
3Viremia
04/2014 - 12/2011
2Virus Diseases (Viral Diseases)
11/2015 - 08/2014
2Fever (Fevers)
08/2014 - 01/2011
2Convalescence
01/2014 - 01/2013
2Thrombocytopenia (Thrombopenia)
11/2013 - 01/2008
2Shock
01/2013 - 01/2008
2Melioidosis
09/2011 - 09/2007
2Nausea
09/2011 - 08/2005
1Communicable Diseases (Infectious Diseases)
11/2015
1Leukopenia
11/2013
1Myocarditis (Carditis)
01/2013
1Arbovirus Infections
01/2013
1Dizziness (Lightheadedness)
09/2011
1Headache (Headaches)
09/2011
1Hepatitis
09/2011
1Sepsis (Septicemia)
09/2007
1Hyponatremia
08/2005
1Diarrhea
08/2005

Drug/Important Bio-Agent (IBA)

12AntibodiesIBA
12/2015 - 03/2004
5AntigensIBA
01/2013 - 03/2004
4VaccinesIBA
11/2015 - 05/2009
4Immunoglobulin G (IgG)IBA
01/2012 - 08/2005
3Viral RNAIBA
11/2015 - 02/2006
3RNA (Ribonucleic Acid)IBA
10/2015 - 09/2011
3Chloroquine (Aralen)FDA LinkGeneric
01/2015 - 01/2006
3Antiviral Agents (Antivirals)IBA
08/2014 - 04/2004
3MDL 28574IBA
08/2014 - 12/2011
3Proteins (Proteins, Gene)IBA
01/2014 - 01/2009
3CytokinesIBA
01/2014 - 01/2011
3Chikungunya virus infectionIBA
01/2013 - 07/2009
2InterferonsIBA
10/2015 - 01/2014
2DNA (Deoxyribonucleic Acid)IBA
07/2015 - 09/2007
2Immunoglobulins (Immunoglobulin)IBA
02/2014 - 01/2013
2ProteomeIBA
01/2014 - 01/2012
2Neutralizing AntibodiesIBA
01/2013 - 01/2011
2Carbon MonoxideIBA
12/2012 - 09/2004
2PeptidesIBA
09/2011 - 01/2009
2Recombinant ProteinsIBA
03/2004 - 03/2004
1Proteasome Endopeptidase Complex (Proteasome)IBA
11/2015
1Fc Receptors (Fc Receptor)IBA
11/2015
1GlucosidasesIBA
08/2014
1Biological Markers (Surrogate Marker)IBA
11/2013
1STF 62247IBA
11/2013
1Arachidonic Acid (Vitamin F)IBA
01/2013
1Intravenous Immunoglobulins (IVIG)FDA Link
01/2013
1curdlan sulfateIBA
01/2013
1DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA
01/2013
1Leukotriene B4IBA
01/2013
1Ribavirin (Virazole)FDA LinkGeneric
01/2013
1Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
01/2013
1C-Reactive ProteinIBA
01/2013
1Immunoglobulin M (IgM)IBA
01/2012
1Glycoproteins (Glycoprotein)IBA
01/2012
1Dengue VaccinesIBA
12/2011
1CAP18 lipopolysaccharide-binding protein (Bac4)IBA
09/2011
1Fc gamma receptor IIBIBA
07/2011
1molecular chaperone GRP78IBA
06/2011
1CCAAT-Enhancer-Binding ProteinsIBA
06/2011
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2011
1Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
01/2011
1MicroRNAs (MicroRNA)IBA
01/2011
1gamma Catenin (Plakoglobin)IBA
01/2011
1Interferon-gamma (Interferon, gamma)IBA
01/2010
1Interleukin-15 (Interleukin 15)IBA
01/2010
1HLA-DR Antigens (HLA-DR)IBA
01/2010
1Doxycycline (Vibramycin)FDA LinkGeneric
03/2008
1Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric
03/2008
1Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link
03/2008
1avian influenza A virus hemagglutininIBA
01/2006
1Urea (Carbamide)FDA LinkGeneric
08/2005
1Nucleocapsid ProteinsIBA
03/2004
1Glutathione Transferase (Glutathione S-Transferase)IBA
03/2004

Therapy/Procedure

1Therapeutics
11/2015
1Resuscitation
01/2013
1Aftercare (After-Treatment)
12/2011
1Ligation
07/2011
1Electrodes (Electrode)
01/2010
1Antibiotic Prophylaxis
03/2008