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Susan O'Brien Selected Research

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

6/2015Monoclonal antibodies in acute lymphoblastic leukemia.
6/2015A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.
5/2015Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
4/2015The role of ponatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia.
4/2015Inotuzumab ozogamicin in B-cell acute lymphoblastic leukemias and non-Hodgkin's lymphomas.
3/2015Prognostic factors for outcome in patients with refractory and relapsed acute lymphocytic leukemia treated with inotuzumab ozogamicin, a CD22 monoclonal antibody.
2/2015Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia.
8/2014The effect of peritransplant minimal residual disease in adults with acute lymphoblastic leukemia undergoing allogeneic hematopoietic stem cell transplantation.
6/2014Phase I and extension study of clofarabine plus cyclophosphamide in patients with relapsed/refractory acute lymphoblastic leukemia.
3/2014Phase II trial of hyper CVAD and dasatinib in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia or blast phase chronic myeloid leukemia.
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Susan O'Brien Research Topics

Disease

111BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
11/2015 - 04/2002
76B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2015 - 02/2002
55Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2015 - 01/2002
54Philadelphia Chromosome
11/2015 - 04/2002
47Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2015 - 01/2002
36Leukemia
07/2015 - 03/2002
36Myelodysplastic Syndromes (Myelodysplastic Syndrome)
03/2015 - 01/2002
25Neoplasms (Cancer)
07/2015 - 09/2002
14Lymphoma (Lymphomas)
07/2015 - 02/2002
13Blast Crisis (Blast Phase)
11/2014 - 05/2002
12Infection
11/2015 - 01/2002
12Hematologic Neoplasms (Hematological Malignancy)
07/2015 - 01/2002
9Acute Promyelocytic Leukemia
05/2015 - 06/2002
9Anemia
11/2013 - 03/2002
8Primary Myelofibrosis (Myelosclerosis)
11/2013 - 09/2002
7Residual Neoplasm
08/2014 - 01/2003
7Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
04/2014 - 06/2003
6Nausea
02/2015 - 12/2003
6Chromosome Aberrations (Chromosome Abnormalities)
12/2008 - 08/2002
5Diarrhea
07/2015 - 08/2002
5Burkitt Lymphoma (Burkitt's Lymphoma)
06/2015 - 03/2002
5Disease Progression
09/2014 - 12/2006
5Hairy Cell Leukemia
10/2011 - 09/2002
5Thrombocytopenia (Thrombopenia)
12/2010 - 09/2002
4Vomiting
01/2015 - 12/2003
4Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2015 - 02/2002
4Neutropenia
04/2014 - 06/2004
4Trisomy (Trisomies)
09/2012 - 08/2002
4Splenomegaly
10/2011 - 03/2002
4Lymphoproliferative Disorders (Lymphoproliferative Disorder)
08/2008 - 09/2005
4Myeloproliferative Disorders (Myeloproliferative Disorder)
07/2007 - 09/2002
3Mucositis
06/2015 - 01/2002
3Fever (Fevers)
07/2014 - 04/2012
3Lymphoid Leukemia
07/2014 - 03/2002
3Lymphocytosis
09/2013 - 09/2011
3Multiple Myeloma
08/2011 - 03/2003
3B-Cell Lymphoma (Lymphoma, B Cell)
04/2011 - 02/2002
3Leukocytosis (Pleocytosis)
12/2010 - 12/2003
3Fibrosis (Cirrhosis)
08/2005 - 07/2004
3Prolymphocytic Leukemia
02/2005 - 02/2002
2Myocardial Infarction
11/2015 - 10/2007

Drug/Important Bio-Agent (IBA)

86imatinib (Gleevec)FDA Link
11/2015 - 05/2002
47Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2015 - 09/2003
34rituximab (Mabthera)FDA Link
06/2015 - 02/2002
33Cytarabine (Cytosar-U)FDA LinkGeneric
01/2015 - 03/2002
31fludarabineIBA
06/2015 - 10/2002
26Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2015 - 01/2002
20dasatinib (BMS 354825)FDA Link
11/2015 - 06/2006
15Monoclonal AntibodiesIBA
06/2015 - 07/2003
15Vincristine (Oncovin)FDA LinkGeneric
05/2015 - 01/2002
13Dexamethasone (Maxidex)FDA LinkGeneric
05/2015 - 01/2002
13alemtuzumab (Campath)FDA Link
08/2011 - 01/2004
124- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)FDA Link
11/2015 - 06/2006
12Interferon-alpha (Interferon Alfa)FDA Link
06/2012 - 04/2002
11Doxorubicin (Adriamycin)FDA LinkGeneric
05/2015 - 01/2002
11InterferonsIBA
06/2012 - 06/2003
10decitabine (5-aza-2'-deoxycytidine)FDA Link
03/2015 - 08/2003
10Phosphotransferases (Kinase)IBA
02/2012 - 12/2003
8Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
05/2015 - 08/2002
8Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2015 - 06/2002
8clofarabine (Clolar)FDA Link
06/2014 - 03/2003
7gemtuzumab (gemtuzumab ozogamicin)FDA Link
10/2014 - 01/2002
7Hemoglobins (Hemoglobin)IBA
02/2014 - 04/2002
6Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
06/2015 - 07/2008
6CMC544 (Inotuzumab Ozogamicin)IBA
04/2015 - 06/2013
6Messenger RNA (mRNA)IBA
12/2011 - 02/2007
6Bcr-Abl tyrosine kinaseIBA
07/2007 - 07/2002
5arsenic trioxide (Trisenox)FDA Link
05/2015 - 05/2003
5Methotrexate (Mexate)FDA LinkGeneric
02/2015 - 03/2002
5L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
02/2009 - 03/2002
5TransferasesIBA
11/2007 - 03/2003
4BilirubinIBA
02/2015 - 04/2012
4homoharringtonineIBA
01/2015 - 04/2002
4Proteasome Endopeptidase Complex (Proteasome)IBA
08/2011 - 03/2008
4Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
04/2011 - 08/2006
4ErythropoietinFDA Link
01/2010 - 04/2002
4laromustine (VNP40101M)IBA
11/2009 - 11/2005
4Topotecan (Hycamtin)FDA LinkGeneric
10/2006 - 03/2003
3oxaliplatin (Eloxatin)FDA LinkGeneric
10/2014 - 01/2008
3Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2014 - 01/2002
3lenalidomide (CC 5013)FDA Link
06/2014 - 11/2009
3CladribineFDA LinkGeneric
10/2011 - 01/2003
3bortezomib (Velcade)FDA Link
08/2011 - 08/2005
3tipifarnib (R115777)IBA
03/2011 - 03/2003
3obatoclaxIBA
10/2010 - 12/2008
3Alkylating AgentsIBA
07/2009 - 01/2004
3purineIBA
07/2009 - 01/2004
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2008 - 08/2002
3AntibodiesIBA
08/2007 - 09/2004
3Reticulin (Reticular Fiber)IBA
08/2005 - 07/2004
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
11/2015 - 10/2014

Therapy/Procedure

48Drug Therapy (Chemotherapy)
11/2015 - 01/2002
10Salvage Therapy
01/2015 - 08/2005
9Stem Cell Transplantation
05/2015 - 09/2002
6Transplants (Transplant)
05/2015 - 09/2006
4Hematopoietic Stem Cell Transplantation
08/2014 - 02/2010
4Aftercare (After-Treatment)
02/2011 - 02/2003
3Transplantation (Transplant Recipients)
05/2015 - 05/2007
3Immunotherapy
06/2013 - 10/2009
3Intravenous Infusions
05/2010 - 02/2005