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Jan Nilsson Selected Research

Apolipoprotein B-100 (Apo B 100)

9/2015Decreased levels of autoantibodies against apolipoprotein B-100 antigens are associated with cardiovascular disease in systemic lupus erythematosus.
1/2014Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.
5/2010Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis.
7/2009Identification of the target for therapeutic recombinant anti-apoB-100 peptide antibodies in human atherosclerotic lesions.
9/2008High plasma concentrations of autoantibodies against native peptide 210 of apoB-100 are related to less coronary atherosclerosis and lower risk of myocardial infarction.
3/2008Autoantibodies against modified apolipoprotein B-100 in relation to low-density lipoprotein size and the metabolic syndrome in otherwise healthy men.
10/2007Autoantibody against the amino acid sequence 661-680 in apo B-100 is associated with decreased carotid stenosis and cardiovascular events.
3/2007Autoimmune responses against the apo B-100 LDL receptor-binding site protect against arterial accumulation of lipids in LDL receptor deficient mice.
2/2007Inhibition of injury-induced arterial remodelling and carotid atherosclerosis by recombinant human antibodies against aldehyde-modified apoB-100.
12/2005Immunization using an Apo B-100 related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E (-/-) mice.
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Jan Nilsson Research Topics

Disease

61Atherosclerosis
10/2015 - 02/2002
26Inflammation
10/2015 - 01/2003
24Atherosclerotic Plaque (Atheroma)
08/2015 - 06/2005
17Cardiovascular Diseases (Cardiovascular Disease)
09/2015 - 05/2003
7Neoplasms (Cancer)
10/2015 - 02/2002
7Neointima
10/2015 - 05/2004
6Hypercholesterolemia
06/2011 - 03/2002
4Carotid Artery Diseases
01/2014 - 02/2007
3Stroke (Strokes)
10/2015 - 01/2014
3Myocardial Infarction
09/2015 - 10/2007
3Rupture
01/2015 - 01/2008
3Coronary Disease (Coronary Heart Disease)
01/2015 - 04/2005
3Hyperglycemia
01/2014 - 01/2010
2Neoplasm Metastasis (Metastasis)
11/2015 - 08/2013
2Transient Ischemic Attack
10/2015 - 08/2015
2Hypertension (High Blood Pressure)
04/2015 - 03/2002
2Disease Progression
03/2013 - 05/2007
2Dyslipidemias (Dyslipidemia)
01/2010 - 04/2005
2Coronary Artery Disease (Coronary Atherosclerosis)
09/2008 - 04/2003
1Amaurosis Fugax
10/2015
1Peripheral Vascular Diseases (Peripheral Vascular Disease)
09/2015
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
09/2015
1Type 2 Diabetes Mellitus (MODY)
07/2015
1Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
01/2015
1Arteritis
03/2013
1Autoimmune Diseases (Autoimmune Disease)
03/2013
1Vascular System Injuries
07/2011

Drug/Important Bio-Agent (IBA)

20oxidized low density lipoproteinIBA
04/2015 - 05/2003
19Apolipoproteins E (ApoE)IBA
10/2015 - 05/2003
17ApolipoproteinsIBA
08/2015 - 02/2002
16Immunoglobulin G (IgG)IBA
10/2015 - 05/2003
15AntigensIBA
09/2015 - 01/2005
14Apolipoprotein B-100 (Apo B 100)IBA
09/2015 - 05/2003
14AntibodiesIBA
10/2012 - 05/2003
10AutoantibodiesIBA
09/2015 - 04/2003
10Lipoproteins (Lipoprotein)IBA
03/2013 - 03/2002
9CholesterolIBA
10/2015 - 12/2005
9CytokinesIBA
08/2015 - 11/2004
8EpitopesIBA
01/2015 - 10/2004
7PeptidesIBA
07/2014 - 10/2007
7VaccinesIBA
05/2013 - 12/2005
7LDL Receptors (LDL Receptor)IBA
06/2011 - 09/2006
6Immunoglobulin M (IgM)IBA
10/2015 - 05/2003
6AutoantigensIBA
03/2013 - 12/2004
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2010 - 11/2004
5Malondialdehyde (Propanedial)IBA
01/2014 - 09/2006
4Biological Markers (Surrogate Marker)IBA
07/2015 - 03/2013
3LipidsIBA
08/2015 - 06/2005
3Apolipoproteins B (ApoB)IBA
07/2014 - 05/2003
3Transcription Factors (Transcription Factor)IBA
01/2014 - 01/2003
3Triglycerides (Triacylglycerol)IBA
01/2014 - 04/2005
3Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
11/2013 - 05/2008
3CollagenIBA
02/2013 - 01/2008
3oil red OIBA
01/2012 - 03/2010
3Cystatin CIBA
01/2008 - 10/2005
2Interleukin-10 (Interleukin 10)IBA
10/2015 - 03/2013
2fibromodulinIBA
08/2015 - 02/2013
2Proteins (Proteins, Gene)IBA
01/2015 - 07/2012
2Glycoproteins (Glycoprotein)IBA
01/2015 - 12/2004
2ElastinIBA
01/2015 - 01/2008
2aluminum sulfate (alum)IBA
07/2014 - 06/2009
2OsteopontinIBA
01/2014 - 02/2010
2Streptozocin (Streptozotocin)FDA Link
01/2014 - 10/2009
21-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA
11/2013 - 06/2012
2low density lipoprotein inhibitorIBA
10/2012 - 04/2003
2Fibronectins (Fibronectin)IBA
07/2012 - 08/2011
2Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2011 - 01/2003
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
01/2010 - 10/2009
2Cysteine Proteases (Cysteine Protease)IBA
01/2008 - 10/2005
2LDL Lipoproteins (beta Lipoproteins)IBA
01/2006 - 04/2003
2Insulin-Like Growth Factor II (Somatomedin A)IBA
10/2003 - 02/2002
1gadolinium ethoxybenzyl DTPAIBA
11/2015
1interleukin-22 (IL-22)IBA
10/2015
1Interleukin-16 (Interleukin 16)IBA
10/2015
1Chemokine CX3CL1IBA
08/2015
1InterferonsIBA
08/2015
1Matrix MetalloproteinasesIBA
07/2015
1Collagen Type IV (Type IV Collagen)IBA
05/2015
1HDL CholesterolIBA
04/2015
1Epidermal Growth Factor (EGF)IBA
01/2015
1Platelet-Derived Growth FactorIBA
01/2015
1Interleukin-5 (Interleukin 5)IBA
01/2015
1DystrophinIBA
01/2015
1heparin-binding EGF-like growth factor (HB-EGF)IBA
01/2015
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
03/2014
1S100 Proteins (S 100 Protein)IBA
01/2014
1A 285222IBA
01/2014
1Plasminogen Activators (Plasminogen Activator)IBA
11/2013
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
11/2013
1Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2013
1ruberythric acid (AlP)IBA
04/2012
1Extracellular Matrix ProteinsIBA
08/2011
1Interleukin-1 (Interleukin 1)IBA
07/2011

Therapy/Procedure

4Carotid Endarterectomy
07/2015 - 01/2015
3Immunomodulation
08/2011 - 01/2005
2Drug Therapy (Chemotherapy)
11/2015 - 08/2013
2Hepatectomy
05/2015 - 08/2013
1Mediterranean Diet
01/2015
1Subcutaneous Infusions
03/2012
1Stents
07/2011