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Mark J Niciu Selected Research

Ketamine

6/2015A single infusion of ketamine improves depression scores in patients with anxious bipolar depression.
5/2015Neural correlates of change in major depressive disorder anhedonia following open-label ketamine.
1/2015Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression.
1/2015Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder.
11/2014Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety.
9/2014Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine.
5/2014Clinical predictors of ketamine response in treatment-resistant major depression.
4/2014Do the dissociative side effects of ketamine mediate its antidepressant effects?
1/2014Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds.
7/2013Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive-compulsive disorder and a history of major depressive disorder.
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Mark J Niciu Research Topics

Disease

13Major Depressive Disorder (Major Depressive Disorders)
11/2015 - 07/2013
7Bipolar Disorder (Mania)
06/2015 - 07/2013
2Schizophrenia (Dementia Praecox)
09/2014 - 10/2012
2Mood Disorders (Mood Disorder)
04/2014 - 10/2013
1Wounds and Injuries (Trauma)
11/2015
1Alcoholism (Alcohol Abuse)
04/2015
1Substance-Related Disorders (Drug Abuse)
01/2014
1Respiratory Insufficiency (Respiratory Failure)
07/2013
1Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
07/2013
1Post-Traumatic Stress Disorders (PTSD)
06/2013
1Menkes Kinky Hair Syndrome (Menkes Disease)
09/2007

Drug/Important Bio-Agent (IBA)

11KetamineFDA LinkGeneric
06/2015 - 06/2013
5N-Methylaspartate (NMDA)IBA
01/2015 - 10/2012
4Glutamic Acid (Glutamate)FDA Link
08/2014 - 10/2012
2Biological Markers (Surrogate Marker)IBA
11/2015 - 04/2014
2Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
06/2015 - 01/2015
2LithiumIBA
06/2015 - 01/2015
2Dopamine (Intropin)FDA LinkGeneric
08/2014 - 10/2013
2Norepinephrine (Noradrenaline)FDA LinkGeneric
08/2014 - 10/2013
2Serotonin (5 Hydroxytryptamine)IBA
08/2014 - 10/2013
2gamma-Aminobutyric Acid (GABA)IBA
01/2014 - 10/2013
2Aminobutyric Acids (Aminobutyric Acid)IBA
01/2014 - 10/2013
1Hydrocortisone (Cortisol)FDA LinkGeneric
11/2015
1Carbon MonoxideIBA
06/2015
1gabapentin (Neurontin)FDA LinkGeneric
04/2015
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
09/2014
1Antipsychotic Agents (Antipsychotics)IBA
09/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
08/2014
1Antidepressive Agents (Antidepressants)IBA
04/2014
1Cocaine (Cocaine HCl)IBA
01/2014
1Glutamate Receptors (Glutamate Receptor)IBA
10/2013
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
10/2012
1CopperIBA
09/2007

Therapy/Procedure

2Drug Therapy (Chemotherapy)
05/2015 - 01/2014
1Anesthesia
07/2013