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Kavindra Nath Selected Research

lonidamine

3/2015Lonidamine induces intracellular tumor acidification and ATP depletion in breast, prostate and ovarian cancer xenografts and potentiates response to doxorubicin.
3/2015Effects of hyperglycemia on lonidamine-induced acidification and de-energization of human melanoma xenografts and sensitization to melphalan.
1/2013(31) P and (1) H MRS of DB-1 melanoma xenografts: lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan.

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Kavindra Nath Research Topics

Disease

6Neoplasms (Cancer)
09/2015 - 02/2009
3Melanoma (Melanoma, Malignant)
03/2015 - 01/2013
2Brain Neoplasms (Brain Tumor)
01/2014 - 02/2009
2Alzheimer Disease (Alzheimer's Disease)
04/2013 - 01/2013
1Breast Neoplasms (Breast Cancer)
09/2015
1Hyperglycemia
03/2015
1Carcinoma (Carcinomatosis)
03/2015
1Ovarian Neoplasms (Ovarian Cancer)
03/2015
1Sleep Disorders
01/2014
1Narcolepsy
01/2014
1Tobacco Use Disorder (Nicotine Dependence)
01/2014
1Sleep Apnea Syndromes (Sleep Apnea)
01/2014
1Fever (Fevers)
01/2013
1Meningitis
02/2009
1Brain Abscess (Abscess, Brain)
02/2009
1Hepatic Encephalopathy
09/2008
1End Stage Liver Disease
07/2008
1Acute Liver Failure (Fulminant Hepatic Failure)
07/2008

Drug/Important Bio-Agent (IBA)

4Lactic AcidFDA LinkGeneric
09/2015 - 02/2009
3triphosphoric acid (triphosphate)IBA
09/2015 - 01/2013
3lonidamineIBA
03/2015 - 01/2013
3Melphalan (Alkeran)FDA LinkGeneric
03/2015 - 01/2013
3Protons (Proton)IBA
02/2009 - 07/2008
2Adenosine Triphosphate (ATP)IBA
03/2015 - 03/2015
2Glutamic Acid (Glutamate)FDA Link
01/2014 - 04/2013
1Estrogens (Estrogen)FDA Link
09/2015
1Phosphocreatine (Neoton)IBA
09/2015
1Antineoplastic Agents (Antineoplastics)IBA
03/2015
1AnthracyclinesIBA
03/2015
1Carbon DioxideIBA
03/2015
1Glucose (Dextrose)FDA LinkGeneric
03/2015
1Mechlorethamine (Nitrogen Mustard)FDA Link
03/2015
1Carbonic AcidIBA
03/2015
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2015
1A-factor (Streptomyces)IBA
03/2015
1CathepsinsIBA
01/2014
1Cocaine (Cocaine HCl)IBA
01/2014
1modafinil (armodafinil)FDA Link
01/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
04/2013
1Inositol (Myoinositol)IBA
01/2013
1Alkylating AgentsIBA
01/2013
1Amino AcidsFDA Link
02/2009
1Biological Markers (Surrogate Marker)IBA
02/2009
1Choline (Choline Chloride)IBA
02/2009
1Mannitol (Osmitrol)FDA LinkGeneric
07/2008

Therapy/Procedure

4Heterologous Transplantation (Xenotransplantation)
09/2015 - 01/2013
1Drug Therapy (Chemotherapy)
01/2013
1Therapeutics
01/2013