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Hiroshi Nakada Selected Research

Tn antigen

2/2015Susceptibility to proteases of anti-Tn-antigen MLS128 binding glycoproteins expressed in human colon cancer cells.
10/2013Characterization of anti-Tn-antigen MLS128 binding proteins involved in inhibiting the growth of human colorectal cancer cells.
8/2013Trimeric Tn antigen on syndecan 1 produced by ppGalNAc-T13 enhances cancer metastasis via a complex formation with integrin α5β1 and matrix metalloproteinase 9.
3/2012pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen.
12/2010Preparation of asialo-agalacto-glycophorin A for screening of anti-Tn antibodies.
2/2009Inhibition of cancer cell growth by anti-Tn monoclonal antibody MLS128.
11/2006Expression of Tn and sialyl-Tn antigens in endometrial cancer: its relationship with tumor-produced cyclooxygenase-2, tumor-infiltrated lymphocytes and patient prognosis.

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Hiroshi Nakada Research Topics

Disease

28Neoplasms (Cancer)
10/2015 - 11/2002
13Colorectal Neoplasms (Colorectal Cancer)
10/2013 - 11/2002
9Neoplasm Metastasis (Metastasis)
08/2013 - 04/2002
8Colonic Neoplasms (Colon Cancer)
02/2015 - 03/2003
4Adenocarcinoma
02/2009 - 01/2003
2Endometriosis (Adenomyosis)
04/2015 - 05/2012
2Inflammation
03/2014 - 01/2014
2Lung Neoplasms (Lung Cancer)
08/2013 - 03/2012
2Ascites
05/2012 - 11/2007
2Carcinoma (Carcinomatosis)
02/2009 - 06/2004
2Pseudomyxoma Peritonei
11/2007 - 11/2007
2Rectal Neoplasms (Rectal Cancer)
10/2004 - 04/2002
1Body Weight (Weight, Body)
01/2014
1Pneumonia (Pneumonitis)
01/2014
1Lung Injury
01/2014
1Fibrosis (Cirrhosis)
01/2014
1Ovarian Neoplasms (Ovarian Cancer)
05/2012
1Hepatocellular Carcinoma (Hepatoma)
05/2012
1Rheumatoid Arthritis
03/2011
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2007
1Appendiceal Neoplasms (Appendix Cancer)
11/2007
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2007
1Endometrial Neoplasms (Endometrial Cancer)
11/2006

Drug/Important Bio-Agent (IBA)

12MucinsIBA
05/2012 - 03/2003
10AntigensIBA
02/2015 - 11/2006
7Tn antigenIBA
02/2015 - 11/2006
6Messenger RNA (mRNA)IBA
07/2007 - 10/2003
5Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
07/2007 - 11/2002
5Fluorouracil (Carac)FDA LinkGeneric
11/2005 - 04/2002
4Conditioned Culture MediaIBA
05/2012 - 03/2003
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2008 - 06/2006
3Carcinoembryonic AntigenIBA
11/2007 - 01/2003
3Thymidylate SynthaseIBA
07/2007 - 10/2003
2Mucin-1 (CA 15-3 Antigen)IBA
10/2015 - 12/2014
2Galectin 3 (LGALS3)IBA
10/2015 - 06/2014
2Glycoproteins (Glycoprotein)IBA
02/2015 - 10/2013
2tranilast (N 5')IBA
03/2014 - 10/2004
2IGF Type 1 Receptor (IGF 1 Receptor)IBA
10/2013 - 02/2009
2Syndecan-1 (Syndecan 1)IBA
08/2013 - 03/2012
2sialosyl-Tn antigenIBA
05/2012 - 07/2008
2Interleukin-6 (Interleukin 6)IBA
03/2011 - 09/2005
2AntibodiesIBA
12/2010 - 02/2009
2EnzymesIBA
07/2007 - 11/2005
2Orotate PhosphoribosyltransferaseIBA
07/2007 - 11/2005
2Scavenger Receptors (Scavenger Receptor)IBA
01/2007 - 09/2005
2Dinoprostone (PGE2)FDA Link
01/2007 - 06/2006
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
11/2006 - 03/2003
2Type I DNA Topoisomerases (Topoisomerase I)IBA
09/2005 - 10/2004
2trioctyl phosphine oxide (TOPO)IBA
09/2005 - 10/2004
2Leucovorin (Folinic Acid)FDA Link
06/2004 - 04/2002
1Mitogen-Activated Protein Kinase 3IBA
10/2015
1Ovarian epithelial cancerIBA
04/2015
1megakaryocyte potentiating factorIBA
04/2015
1Biological Markers (Surrogate Marker)IBA
04/2015
1Peptide Hydrolases (Proteases)IBA
02/2015
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
12/2014
1Transcription Factor RelAIBA
12/2014
1Carbon MonoxideIBA
12/2014
1Tryptophan (L-Tryptophan)FDA Link
03/2014
1indium-bleomycinIBA
01/2014
1Bleomycin (Blenoxane)FDA LinkGeneric
01/2014
1Lysosphingolipid ReceptorsIBA
01/2014
1Carrier Proteins (Binding Protein)IBA
10/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
08/2013
1A-Form DNA (A-DNA)IBA
08/2013
1src-Family KinasesIBA
08/2013
1PolysaccharidesIBA
05/2012
1HydrogenIBA
05/2012
1NAD (NADH)IBA
05/2012
1CytokinesIBA
03/2011
1Interleukin-12 (IL 12)IBA
11/2010
1Growth Factor ReceptorsIBA
02/2009
1CarbohydratesIBA
02/2009
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
02/2009
1Vascular Endothelial Growth Factor CIBA
12/2008
1Complementary DNA (cDNA)IBA
07/2008
1Cisplatin (Platino)FDA LinkGeneric
11/2007
1ParaffinIBA
11/2007
1Thymidine PhosphorylaseIBA
07/2007
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
11/2006
1Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
11/2006
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2006
1SynaptophysinIBA
01/2006
1irinotecan (Camptosar)FDA LinkGeneric
09/2005
1degradable starch microspheresIBA
10/2004
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2004
1Mitomycin (Mitomycin-C)FDA LinkGeneric
10/2004
1Glutathione S-Transferase piIBA
10/2004

Therapy/Procedure

7Drug Therapy (Chemotherapy)
07/2007 - 04/2002
4Therapeutics
02/2015 - 12/2010
3Ligation
10/2015 - 10/2004
3Laparotomy
04/2011 - 01/2003
1Electrodes (Electrode)
05/2012
1Subcutaneous Injections
03/2012
1Immunomodulation
11/2010
1Radiotherapy
11/2007
1Heterologous Transplantation (Xenotransplantation)
06/2006
1Oral Administration
06/2006
1Cholecystectomy
10/2004
1Hepatectomy
10/2004