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Rodney F Minchin Selected Research

N-acetyltransferase 1

1/2022Polymorphism in the human arylamine N-acetyltransferase 1 gene 3'-untranslated region determines polyadenylation signal usage.
1/2020Modulation of Human Arylamine N-Acetyltransferase 1 Activity by Lysine Acetylation: Role of p300/CREB-Binding Protein and Sirtuins 1 and 2.
11/2019Arylamine N-Acetyltransferase 1 Regulates Expression of Matrix Metalloproteinase 9 in Breast Cancer Cells: Role of Hypoxia-Inducible Factor 1-α.
1/2019Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex.
7/2018Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance.
1/2018Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability.
2/2017Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway.
1/2012Arylamine N-acetyltransferase 1: a novel drug target in cancer development.
1/2011Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells.
5/2010Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1.
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Rodney F Minchin Research Topics

Disease

20Neoplasms (Cancer)
01/2022 - 05/2004
4Breast Neoplasms (Breast Cancer)
01/2021 - 02/2010
3Neurodegenerative Diseases (Neurodegenerative Disease)
11/2013 - 09/2010
3Schizophrenia (Dementia Praecox)
09/2010 - 01/2008
2Prostatic Neoplasms (Prostate Cancer)
02/2011 - 01/2007
2Spinal Dysraphism (Spina Bifida)
01/2011 - 01/2007
1Kaposi Sarcoma (Kaposi's Sarcoma)
10/2021
1Neoplasm Metastasis (Metastasis)
01/2019
1Lymphatic Metastasis
01/2019
1Starvation
01/2018
1Colonic Neoplasms (Colon Cancer)
01/2018
1Connective Tissue Diseases (Connective Tissue Disease)
06/2015
1Triple Negative Breast Neoplasms
04/2015
1Inflammation (Inflammations)
01/2011
1Adenocarcinoma
02/2010
1Melanoma (Melanoma, Malignant)
01/2006
1Glucocorticoid Receptor Deficiency
01/2003

Drug/Important Bio-Agent (IBA)

12N-acetyltransferase 1IBA
01/2022 - 05/2004
10EnzymesIBA
01/2022 - 01/2007
9Pharmaceutical PreparationsIBA
01/2022 - 01/2006
4Arylamine N-AcetyltransferaseIBA
12/2020 - 01/2007
3Proteins (Proteins, Gene)FDA Link
11/2019 - 05/2010
3Folic Acid (Vitamin M)FDA LinkGeneric
01/2012 - 01/2007
21-dodecylpyridoxal (PLD)IBA
10/2021 - 01/2021
2liposomal doxorubicin (Doxil)FDA Link
10/2021 - 01/2021
2Messenger RNA (mRNA)IBA
11/2019 - 07/2018
2Cadherins (E-Cadherin)IBA
01/2018 - 02/2011
2Small Interfering RNA (siRNA)IBA
01/2018 - 04/2015
2Peptidylprolyl Isomerase (Prolyl Isomerase)IBA
01/2011 - 09/2010
2CarcinogensIBA
02/2010 - 01/2007
1Oxygen (Dioxygen)IBA
01/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1XenobioticsIBA
01/2020
1Metalloproteases (Metalloproteinases)IBA
11/2019
1Matrix Metalloproteinases (MMPs)IBA
11/2019
1Hypoxia-Inducible Factor 1IBA
11/2019
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
11/2019
1Peptides (Polypeptides)IBA
01/2019
1Estrogen ReceptorsIBA
07/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1Methionine (L-Methionine)FDA Link
02/2017
1beta-cyclodextrin tetradecasulfate (CTDS)IBA
06/2015
1Antinuclear AntibodiesIBA
06/2015
1Dopamine (Intropin)FDA LinkGeneric
11/2013
1monoamine-sulfating phenol sulfotransferaseIBA
11/2013
1Environmental CarcinogensIBA
01/2012
1Fibrinogen (Factor I)FDA Link
01/2011
1Macrophage-1 Antigen (Macrophage 1 Antigen)IBA
01/2011
1theasinensin AIBA
01/2011
1Histone Deacetylase InhibitorsIBA
01/2011
1trichostatin A (A 300)IBA
01/2011
1(Z)- 5- (2'- hydroxybenzylidene)- 2- thioxothiazolidin- 4- oneIBA
02/2010
1SulfotransferasesIBA
02/2009
15' Untranslated Regions (5' UTR)IBA
01/2008
1AndrogensIBA
01/2007
1PolyaminesIBA
01/2006
1N(1),N(11)-diethylnorspermineIBA
01/2006
1Hormones (Hormone)IBA
01/2003
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
01/2003

Therapy/Procedure

3Drug Therapy (Chemotherapy)
01/2021 - 01/2012
3Therapeutics
01/2021 - 02/2011