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Jean-Luc Mainardi Selected Research

Clavulanic Acid (Potassium Clavulanate)

9/2015Hydrolysis of clavulanate by Mycobacterium tuberculosis β-lactamase BlaC harboring a canonical SDN motif.
5/2015Impact of β-lactamase inhibition on the activity of ceftaroline against Mycobacterium tuberculosis and Mycobacterium abscessus.
12/2013In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D-transpeptidases and inactivation of these enzymes by carbapenems.
6/2011Activity of carbapenems combined with clavulanate against murine tuberculosis.
4/2010The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin.

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Jean-Luc Mainardi Research Topics

Disease

12Infection
08/2015 - 08/2004
8Endocarditis
02/2014 - 12/2003
7Tuberculosis (Tuberculoses)
09/2015 - 06/2008
3Rupture
12/2013 - 10/2007
2Mediastinitis
09/2014 - 12/2009
2Pneumonia (Pneumonitis)
02/2010 - 10/2007
2Sepsis (Septicemia)
11/2009 - 10/2007
1Critical Illness (Critically Ill)
09/2014
1Body Weight (Weight, Body)
09/2014
1Staphylococcal Infections
09/2014
1Anemia
01/2013
1Autoimmune Diseases (Autoimmune Disease)
07/2010
1Opportunistic Infections (Opportunistic Infection)
02/2010
1Bacteremia
09/2008
1Diabetes Mellitus
01/2007
1Heart Failure
01/2007
1Abscess
01/2007
1Bacterial Infections (Bacterial Infection)
09/2003
1Bartonella Infections (Bartonellosis)
01/2003

Drug/Important Bio-Agent (IBA)

5Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
09/2015 - 04/2010
5ImipenemFDA Link
04/2015 - 10/2007
5Anti-Bacterial Agents (Antibiotics)IBA
11/2009 - 09/2003
3Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric
04/2015 - 03/2014
3beta-Lactamases (beta-Lactamase)IBA
01/2015 - 06/2008
3VancomycinFDA LinkGeneric
09/2014 - 01/2011
3Carbapenems (Carbapenem Antibiotics)IBA
12/2013 - 06/2011
2LactamsIBA
09/2015 - 04/2015
2CreatinineIBA
09/2014 - 01/2007
2meropenem (Merrem)FDA LinkGeneric
08/2012 - 06/2011
2ertapenem (Invanz)FDA Link
08/2012 - 06/2011
2Cephalosporins (Cephalosporin Antibiotics)IBA
08/2012 - 09/2008
2beta-LactamsIBA
11/2009 - 10/2006
2DNA (Deoxyribonucleic Acid)IBA
12/2003 - 01/2003
1Clindamycin (Cleocin)FDA LinkGeneric
08/2015
1Rifampin (Rifampicin)FDA LinkGeneric
08/2015
1Ofloxacin (Levofloxacin)FDA LinkGeneric
08/2015
1T 91825IBA
05/2015
1Ceftazidime (Fortum)FDA LinkGeneric
04/2015
1AntibodiesIBA
02/2014
1Peptidoglycan (Murein)IBA
12/2013
1AntigensIBA
07/2013
1IodineIBA
01/2013
1AminoglycosidesIBA
01/2013
1Ampicillin (Omnipen)FDA LinkGeneric
01/2013
1Ceftriaxone (Ceftriaxon)FDA LinkGeneric
08/2012
1doripenemFDA Link
08/2012
1Cefotaxime (Kendrick)FDA LinkGeneric
08/2012
1Cephalothin (Cefalotin)FDA Link
08/2012
1Isoniazid (Ftivazide)FDA LinkGeneric
06/2011
1Antinuclear AntibodiesIBA
07/2010
1Amoxicillin (Wymox)FDA LinkGeneric
04/2010
1Insulin (Novolin)FDA Link
01/2007
1GlycopeptidesIBA
10/2006
1tenaxIBA
08/2004
1Ribosomal DNA (rDNA)IBA
12/2003

Therapy/Procedure

2Catheters
01/2015 - 11/2009
2Homologous Transplantation (Allograft)
03/2005 - 08/2004
1Sternotomy
09/2014
1Intravenous Infusions
01/2011
1Hematopoietic Stem Cell Transplantation
02/2010
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
12/2009
1Mechanical Ventilators (Ventilator)
10/2007
1Joint Prosthesis
09/2006
1Hip Prosthesis
09/2006