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Derrick F MacFabe Selected Research

Volatile Fatty Acids

1/2015Enteric short-chain fatty acids: microbial messengers of metabolism, mitochondria, and mind: implications in autism spectrum disorders.
12/2014Sexually dimorphic effects of prenatal exposure to propionic acid and lipopolysaccharide on social behavior in neonatal, adolescent, and adult rats: implications for autism spectrum disorders.
1/2014Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders.
1/2007Neurobiological effects of intraventricular propionic acid in rats: possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders.

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Derrick F MacFabe Research Topics

Disease

8Pervasive Child Development Disorders
02/2015 - 01/2007
2Autistic Disorder (Autism)
02/2015 - 05/2008
2Seizures (Seizure)
02/2015 - 01/2007
1Mitochondrial Diseases (Mitochondrial Disease)
01/2015
1Inflammation
01/2014

Drug/Important Bio-Agent (IBA)

8propionic acid (potassium propionate)IBA
02/2015 - 01/2007
4Volatile Fatty AcidsIBA
01/2015 - 01/2007
1Carbon MonoxideIBA
01/2015
1Neuronal Cell Adhesion MoleculesIBA
01/2014
1Butyric Acid (Butanoic Acid)IBA
01/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2014
1Gastrointestinal AgentsIBA
02/2011
1acylcarnitineIBA
04/2010

Therapy/Procedure

2Intraventricular Infusions
04/2010 - 01/2007