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Gabriel Lopez-Berestein Selected Research

Small Interfering RNA (siRNA)

12/2015Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis.
3/2015STAMP2 increases oxidative stress and is critical for prostate cancer.
2/2015Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth.
1/2015CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis.
12/2014Therapeutic silencing of KRAS using systemically delivered siRNAs.
7/2014Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer.
5/2014EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer.
2/2014Liposomal siRNA nanocarriers for cancer therapy.
1/2014Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
1/20142'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
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Gabriel Lopez-Berestein Research Topics

Disease

97Neoplasms (Cancer)
01/2016 - 01/2004
44Ovarian Neoplasms (Ovarian Cancer)
07/2015 - 08/2006
17Neoplasm Metastasis (Metastasis)
10/2015 - 01/2008
11Breast Neoplasms (Breast Cancer)
12/2014 - 07/2002
10Carcinoma (Carcinomatosis)
02/2015 - 08/2006
8Acute Promyelocytic Leukemia
02/2014 - 05/2002
6Prostatic Neoplasms (Prostate Cancer)
03/2015 - 05/2003
5Leukemia
07/2013 - 05/2002
5Pancreatic Neoplasms (Pancreatic Cancer)
04/2010 - 03/2007
4Colorectal Neoplasms (Colorectal Cancer)
04/2015 - 01/2008
4Melanoma (Melanoma, Malignant)
05/2011 - 12/2005
3Anoxia (Hypoxia)
01/2014 - 01/2008
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2012 - 05/2002
2Hepatocellular Carcinoma (Hepatoma)
01/2016 - 07/2013
2Colonic Neoplasms (Colon Cancer)
12/2014 - 06/2008
2Lung Neoplasms (Lung Cancer)
12/2014 - 03/2014
2Atherosclerotic Plaque (Atheroma)
09/2014 - 08/2010
1Anemia
11/2015
1Adenocarcinoma
11/2014
1Cardiovascular Diseases (Cardiovascular Disease)
09/2014
1Osteoporosis
08/2014
1Skin Neoplasms (Skin Cancer)
08/2014

Drug/Important Bio-Agent (IBA)

53Small Interfering RNA (siRNA)IBA
12/2015 - 08/2005
171,2-oleoylphosphatidylcholine (DOPC)IBA
12/2015 - 08/2005
13Liposomes (Liposome)IBA
09/2014 - 07/2002
13Tretinoin (Retinoic Acid)FDA LinkGeneric
02/2014 - 05/2002
11MicroRNAs (MicroRNA)IBA
10/2015 - 06/2011
10Messenger RNA (mRNA)IBA
03/2015 - 07/2002
10docetaxel (Taxotere)FDA Link
07/2014 - 08/2006
9Cisplatin (Platino)FDA LinkGeneric
07/2015 - 05/2005
9PlatinumIBA
05/2014 - 05/2005
6ChitosanIBA
10/2015 - 08/2010
6Focal Adhesion Protein-Tyrosine KinasesIBA
07/2014 - 08/2006
6Proteins (Proteins, Gene)IBA
07/2013 - 08/2002
5Paclitaxel (Taxol)FDA LinkGeneric
01/2015 - 08/2005
5Ovarian epithelial cancerIBA
07/2014 - 01/2011
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2013 - 08/2006
5Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2013 - 10/2007
4Interleukin-8 (Interleukin 8)IBA
01/2013 - 03/2008
4taxaneIBA
11/2011 - 03/2008
4HormonesIBA
12/2010 - 10/2007
3Biological Markers (Surrogate Marker)IBA
07/2015 - 08/2011
3CytokinesIBA
05/2015 - 05/2010
3Transcription Factors (Transcription Factor)IBA
01/2015 - 10/2012
3Cyclin D1IBA
01/2013 - 07/2002
3arsenic trioxide (Trisenox)FDA Link
01/2012 - 07/2008
3Phosphotransferases (Kinase)IBA
08/2010 - 08/2007
3transglutaminase 2IBA
05/2010 - 07/2008
3imatinib (Gleevec)FDA Link
01/2010 - 05/2007
3Protein Kinases (Protein Kinase)IBA
05/2007 - 05/2002
2Sirolimus (Rapamycin)FDA Link
01/2016 - 07/2013
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
05/2015 - 11/2008
2Caspase 3 (Caspase-3)IBA
01/2015 - 07/2014
2DiphosphonatesIBA
11/2014 - 08/2014
2Androgen Receptors (Androgen Receptor)IBA
07/2013 - 12/2010
2SiliconIBA
04/2013 - 05/2010
2Cadherins (E-Cadherin)IBA
02/2013 - 05/2010
2Estrogens (Estrogen)FDA Link
01/2013 - 01/2012
2Doxorubicin (Adriamycin)FDA LinkGeneric
10/2012 - 01/2012
2Interleukin-6 (Interleukin 6)IBA
02/2012 - 10/2007
2DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
01/2012 - 11/2011
2Neuropilin-2IBA
01/2011 - 01/2008
2RelaxinIBA
12/2010 - 04/2009
2Epinephrine (Adrenaline)FDA LinkGeneric
05/2010 - 11/2007
2TamoxifenFDA LinkGeneric
04/2010 - 07/2002
2DNA (Deoxyribonucleic Acid)IBA
04/2010 - 12/2008
2gemcitabineFDA Link
12/2008 - 04/2008
2thiazolyl blueIBA
12/2008 - 01/2008
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
11/2007 - 08/2006
2Adrenergic Receptors (Adrenergic Receptor)IBA
11/2007 - 08/2006
2retinoic acid receptor alphaIBA
06/2006 - 09/2004
2Antisense OligonucleotidesIBA
01/2004 - 11/2003
1Large Neutral Amino Acid-Transporter 1IBA
01/2016
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
01/2016
1Ceruloplasmin (Ferroxidase)IBA
12/2015
1Untranslated RNA (Noncoding RNA)IBA
12/2015
1ErythropoietinFDA Link
11/2015
1zoledronic acid (zoledronate)FDA Link
05/2015
1Carbon MonoxideIBA
04/2015
1tumor-associated antigen GA733IBA
04/2015
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
02/2015
1Cyclin-Dependent Kinase 5IBA
01/2015
1VimentinIBA
01/2015
1albumin-bound paclitaxelFDA Link
11/2014
1130-nm albumin-bound paclitaxelIBA
11/2014
1ApolipoproteinsIBA
09/2014
1Apolipoproteins E (ApoE)IBA
09/2014
1Clodronic Acid (Clodronate)IBA
08/2014
1Tyrosine (L-Tyrosine)FDA Link
07/2014
1polylactic acid-polyglycolic acid copolymer (PLGA)IBA
07/2014
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2014
1antineoplaston A10 (A 10)IBA
06/2014
1glycogen synthase kinase 3 betaIBA
05/2014
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
05/2014

Therapy/Procedure

15Drug Therapy (Chemotherapy)
07/2015 - 02/2005
14Heterologous Transplantation (Xenotransplantation)
10/2015 - 11/2007
2Therapeutics
06/2015 - 02/2014
2Intravenous Injections
01/2013 - 11/2007
2Injections
12/2010 - 04/2009
1Ovariectomy (Oophorectomy)
08/2014