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David M Loeb Selected Research

samarium Sm-153 lexidronam (Quadramet)

6/2013Beyond Palliation: Therapeutic Applications of 153Samarium-EDTMP.
12/2010Tandem dosing of samarium-153 ethylenediamine tetramethylene phosphoric acid with stem cell support for patients with high-risk osteosarcoma.
6/2009Dose-finding study of 153Sm-EDTMP in patients with poor-prognosis osteosarcoma.

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David M Loeb Research Topics

Disease

36Neoplasms (Cancer)
02/2024 - 08/2002
12Sarcoma (Soft Tissue Sarcoma)
01/2020 - 12/2011
11Ewing Sarcoma (Sarcoma, Ewing)
02/2024 - 11/2010
10Osteosarcoma (Osteogenic Sarcoma)
01/2020 - 01/2009
7Neoplasm Metastasis (Metastasis)
10/2020 - 10/2015
5Hematologic Neoplasms (Hematological Malignancy)
12/2016 - 06/2013
4Leukemia
12/2016 - 12/2009
3Residual Neoplasm
01/2021 - 07/2014
3Chordoma
01/2017 - 10/2011
3Aplastic Anemia (Anemia, Hypoplastic)
11/2016 - 12/2007
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2023 - 07/2014
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2018 - 08/2002
2Wilms Tumor (Wilm's Tumor)
10/2018 - 12/2016
2Pain (Aches)
12/2016 - 06/2013
2Hypoxia (Hypoxemia)
01/2015 - 12/2011
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
07/2014 - 07/2014
2Disease Progression
07/2014 - 01/2013
2Infections
11/2009 - 04/2008
1Respiratory Insufficiency (Respiratory Failure)
01/2023
1Pneumonia (Pneumonitis)
01/2023
1Rhabdoid Tumor (Rhabdoid Tumors)
10/2022
1Neuroblastoma
08/2021
1Peripheral Nervous System Diseases (PNS Diseases)
02/2020
1Peripheral Nervous System Neoplasms
01/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2020
1Rhabdomyosarcoma
02/2018
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2018
1Alveolar Rhabdomyosarcoma
10/2017
1Circulating Neoplastic Cells
10/2017
1Hemorrhage
10/2017
1Proteinuria
10/2017
1Embolism (Embolus)
10/2017
1Hypertension (High Blood Pressure)
10/2017
1Thrombosis (Thrombus)
10/2017
1Wounds and Injuries (Trauma)
10/2017

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
02/2024 - 06/2006
6Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2017 - 05/2003
4Transcription Factors (Transcription Factor)IBA
01/2015 - 12/2009
4Small Interfering RNA (siRNA)IBA
01/2015 - 10/2011
3Cisplatin (Platino)FDA LinkGeneric
01/2023 - 10/2017
3EWS-FLI fusion proteinIBA
01/2021 - 11/2010
3Dasatinib (BMS 354825)FDA Link
01/2018 - 03/2016
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2017 - 12/2011
3samarium Sm-153 lexidronam (Quadramet)FDA Link
06/2013 - 06/2009
3phosphonic acidIBA
06/2013 - 06/2009
3Samarium-153IBA
07/2011 - 06/2009
2RNA Helicases (RNA Helicase)IBA
02/2024 - 06/2023
2Chimeric Antigen ReceptorsIBA
01/2023 - 01/2015
2Bortezomib (Velcade)FDA Link
08/2021 - 06/2013
2RNA (Ribonucleic Acid)IBA
01/2021 - 10/2017
2DNA (Deoxyribonucleic Acid)IBA
01/2021 - 10/2016
2Antineoplastic Agents (Antineoplastics)IBA
02/2020 - 03/2011
2PlatinumIBA
02/2020 - 04/2005
2Docetaxel (Taxotere)FDA Link
01/2020 - 06/2013
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2018 - 01/2015
2Monoclonal AntibodiesIBA
10/2017 - 04/2016
2Bevacizumab (Avastin)FDA Link
10/2017 - 05/2014
2WT1 ProteinsIBA
12/2016 - 12/2011
2AntigensIBA
12/2016 - 01/2015
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2023
1tisagenlecleucelIBA
01/2023
1Etanercept (Enbrel)FDA Link
01/2023
1pembrolizumabIBA
10/2022
1Carrier Proteins (Binding Protein)IBA
08/2021
1Proteasome Endopeptidase Complex (Proteasome)IBA
08/2021
1Proteasome InhibitorsIBA
08/2021
1selinexorIBA
08/2021
1Nucleic AcidsIBA
01/2021
1Cell-Free Nucleic AcidsIBA
01/2021
1plerixaforFDA Link
01/2021
1S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA
10/2020
1Carboplatin (JM8)FDA LinkGeneric
02/2020
1Oxaliplatin (Eloxatin)FDA LinkGeneric
02/2020
1taxaneIBA
01/2020
1saracatinibIBA
01/2020
1Cysteine (L-Cysteine)FDA Link
01/2020
1GemcitabineFDA Link
01/2020
1130-nm albumin-bound paclitaxelIBA
01/2020
1liposomal doxorubicin (Doxil)FDA Link
01/2018
1IronIBA
01/2018
1temsirolimusFDA Link
01/2018
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2018
1Sunitinib (Sutent)FDA Link
01/2018
1Imatinib Mesylate (Gleevec)FDA Link
01/2018
1SulfurIBA
01/2018
1regorafenibIBA
01/2018
1Succinate Dehydrogenase (Fumarate Reductase)IBA
01/2018
1LGK974IBA
10/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2017

Therapy/Procedure

25Therapeutics
01/2023 - 08/2002
18Drug Therapy (Chemotherapy)
10/2020 - 08/2002
6Transplantation
12/2016 - 01/2009
4Hematopoietic Stem Cell Transplantation
10/2018 - 03/2011
4Surgical Amputation (Amputations)
10/2017 - 01/2009
2Cell Transplantation
01/2023 - 07/2014
2Aftercare (After-Treatment)
01/2023 - 05/2003
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
12/2017 - 01/2016
2Radiotherapy
06/2013 - 06/2009
2Immunotherapy
01/2009 - 05/2007
1Bioreactors (Bioreactor)
11/2018