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Quentin Liu Selected Research

aurora kinase (aurora A kinase)

1/2015A novel compound against oncogenic Aurora kinase A overcomes imatinib resistance in chronic myeloid leukemia cells.
9/2014Aurora kinase a suppresses metabolic stress-induced autophagic cell death by activating mTOR signaling in breast cancer cells.
8/2014A novel small molecule aurora kinase inhibitor attenuates breast tumor-initiating cells and overcomes drug resistance.
11/2013Inhibition of mTOR pathway sensitizes acute myeloid leukemia cells to aurora inhibitors by suppression of glycolytic metabolism.
12/2012Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells.
8/2009Inhibition of Aurora-A results in increased cell death in 3-dimensional culture microenvironment, reduced migration and is associated with enhanced radiosensitivity in human nasopharyngeal carcinoma.
7/2008Aurora kinase small molecule inhibitor destroys mitotic spindle, suppresses cell growth, and induces apoptosis in oral squamous cancer cells.
5/2008ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensional culture.
3/2008Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia.

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Quentin Liu Research Topics

Disease

23Neoplasms (Cancer)
11/2015 - 05/2008
6Breast Neoplasms (Breast Cancer)
03/2015 - 11/2010
5Lung Neoplasms (Lung Cancer)
04/2015 - 01/2014
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2015 - 03/2008
4Neoplasm Metastasis (Metastasis)
02/2015 - 11/2010
3Carcinoma (Carcinomatosis)
02/2015 - 05/2008
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2015 - 03/2014
2Polyploidy
08/2015 - 11/2013
2Adenocarcinoma
09/2014 - 01/2013
2Acute Promyelocytic Leukemia
01/2014 - 01/2011
2Leukemia
11/2011 - 03/2008
2Aneuploidy (Aneuploid)
07/2008 - 05/2008
1Fatigue
11/2015
1Flatulence
11/2015
1Diarrhea
11/2015
1Pain (Aches)
02/2015
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2015
1Rheumatic Fever (Acute Articular Rheumatism)
10/2014
1Epilepsy (Aura)
08/2014
1Tics (Tic)
08/2014
1Infection
01/2014
1Lymphatic Metastasis
01/2014
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2014
1Colorectal Neoplasms (Colorectal Cancer)
02/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2013
1Anoxia (Hypoxia)
08/2012
1Neuroblastoma
02/2010
1Stomach Neoplasms (Stomach Cancer)
02/2009
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2009
1Demyelinating Diseases (Demyelinating Disease)
01/2009
1Inflammation
01/2009
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2008

Drug/Important Bio-Agent (IBA)

9Phosphotransferases (Kinase)IBA
08/2015 - 11/2007
9aurora kinase (aurora A kinase)IBA
01/2015 - 03/2008
6VX680IBA
11/2013 - 03/2008
34- (4- (N- benzoylamino)anilino)- 6- methoxy- 7- (3- (1- morpholino)propoxy)quinazolineIBA
08/2015 - 05/2008
3Cadherins (E-Cadherin)IBA
03/2015 - 10/2008
3Sirolimus (Rapamycin)FDA Link
09/2014 - 11/2013
2imatinib (Gleevec)FDA Link
01/2015 - 10/2014
2Carbon MonoxideIBA
10/2014 - 08/2012
2Cisplatin (Platino)FDA LinkGeneric
01/2014 - 01/2014
2Nasopharyngeal carcinomaIBA
08/2012 - 02/2010
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2010 - 01/2009
2Caspase 3 (Caspase-3)IBA
08/2009 - 05/2008
2Histones (Histone)IBA
07/2008 - 05/2008
1ABT 263IBA
08/2015
1Small Interfering RNA (siRNA)IBA
04/2015
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2015
1Keratin-18 (Keratin 18)IBA
03/2015
1flubendazoleIBA
03/2015
1Fluorouracil (Carac)FDA LinkGeneric
03/2015
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2015
1VimentinIBA
03/2015
1nalmefene (Revex)FDA Link
02/2015
1Morphine (MS Contin)FDA LinkGeneric
02/2015
1salinomycinIBA
02/2015
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2015
1Adenocarcinoma of lungIBA
10/2014
1ChromatinIBA
10/2014
1LuciferasesIBA
10/2014
1Trans-Activators (Trans-Acting Factor)IBA
10/2014
1Carrier Proteins (Binding Protein)IBA
10/2014
1Auranofin (Ridaura)FDA Link
10/2014
1Biotin (Vitamin H)FDA Link
10/2014
1StreptavidinIBA
10/2014
1tebufenozide (Mimic)IBA
09/2014
1Proteins (Proteins, Gene)IBA
09/2014
1Epirubicin (Ellence)FDA LinkGeneric
08/2014
1mangostinIBA
03/2014
1arsenic trioxide (Trisenox)FDA Link
01/2014
1bufadienolideIBA
01/2014
1chan suIBA
01/2014
1Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2014
1Paclitaxel (Taxol)FDA LinkGeneric
01/2014
1Amphibian VenomsIBA
01/2014
1phosphatidylethanolamineIBA
01/2014
1Chloroquine (Aralen)FDA LinkGeneric
01/2014
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
01/2014
1PlatinumIBA
01/2014
1Lactic AcidFDA LinkGeneric
11/2013
1Glucose (Dextrose)FDA LinkGeneric
11/2013
1Deoxyglucose (2 Deoxy D glucose)IBA
11/2013
1Transcription Factors (Transcription Factor)IBA
01/2013
1CurcuminIBA
01/2011
1Daunorubicin (Cerubidine)FDA LinkGeneric
01/2011
1Actins (F Actin)IBA
11/2010
1Mitomycin (Mitomycin-C)FDA LinkGeneric
02/2010
1Ciliary Neurotrophic Factor (CNTF)IBA
01/2009
1NF-kappaB inhibitor alphaIBA
01/2009
1Insulin (Novolin)FDA Link
01/2009
1beta CateninIBA
10/2008
1PeptidesIBA
08/2008
1Monoclonal AntibodiesIBA
08/2008

Therapy/Procedure

5Heterologous Transplantation (Xenotransplantation)
04/2015 - 01/2014
5Drug Therapy (Chemotherapy)
01/2014 - 01/2009
1Chinese Traditional Medicine (Traditional Chinese Medicine)
11/2015
1Massage (Reflexology)
11/2015
1Intraperitoneal Injections
03/2015
1Transplantation (Transplant Recipients)
11/2011
1Lymph Node Excision (Lymph Node Dissection)
02/2009