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Heather A Leitch Selected Research

Chelation Therapy (Therapy, Chelation)

12/2022A natural history of lower-risk myelodysplastic syndromes with ring sideroblasts: an analysis of the MDS-CAN registry.
9/2019Hematologic improvement with iron chelation therapy in myelodysplastic syndromes: Clinical data, potential mechanisms, and outstanding questions.
1/2019Delayed time from RBC transfusion dependence to first cardiac event in lower IPSS risk MDS patients receiving iron chelation therapy.
1/2018Iron chelation therapy in lower IPSS risk myelodysplastic syndromes; which subtypes benefit?
1/2018Iron overload in lower international prognostic scoring system risk patients with myelodysplastic syndrome receiving red blood cell transfusions: Relation to infections and possible benefit of iron chelation therapy.
10/2017Overall survival in lower IPSS risk MDS by receipt of iron chelation therapy, adjusting for patient-related factors and measuring from time of first red blood cell transfusion dependence: an MDS-CAN analysis.
6/2016Hematologic improvement with iron chelation therapy in acquired anemias.
1/2015Durable Red Blood Cell Transfusion Independence in a Patient with an MDS/MPN Overlap Syndrome Following Discontinuation of Iron Chelation Therapy.
11/2012Improved survival with iron chelation therapy for red blood cell transfusion dependent lower IPSS risk MDS may be more significant in patients with a non-RARS diagnosis.
1/2011Optimizing therapy for iron overload in the myelodysplastic syndromes: recent developments.
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Heather A Leitch Research Topics

Disease

14Myelodysplastic Syndromes (Myelodysplastic Syndrome)
11/2023 - 12/2007
14Iron Overload
01/2023 - 12/2007
4Infections
01/2018 - 12/2004
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2023 - 12/2021
3Anemia
06/2016 - 02/2013
3Acquired Immunodeficiency Syndrome (AIDS)
01/2012 - 09/2007
3Neoplasms (Cancer)
04/2010 - 06/2005
2Frailty
01/2023 - 01/2016
2Leukemia
01/2023 - 04/2009
2Lymphoma (Lymphomas)
09/2007 - 09/2004
1VEXAS syndrome
06/2023
1Cardiovascular Diseases (Cardiovascular Disease)
01/2019
1Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
04/2018
1Hemolysis
04/2018
1Thrombosis (Thrombus)
04/2018
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2018
1HIV Infections (HIV Infection)
01/2018
1Hematologic Neoplasms (Hematological Malignancy)
05/2017
1Fatigue
01/2016
1Castleman Disease (Castleman's Disease)
05/2015
1Body Weight (Weight, Body)
12/2013
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2012
1beta-Thalassemia (Cooley's Anemia)
01/2011
1Hodgkin Disease (Hodgkin's Disease)
04/2010
1Primary Myelofibrosis (Myelosclerosis)
03/2010
1Cytopenia
01/2010
1Multiple Myeloma
08/2008
1Non-Hodgkin Lymphoma (Lymphosarcoma)
06/2005
1Latent Infection
12/2004
1Pathologic Complete Response
09/2004
1Disease Progression
09/2004
1Plasmablastic Lymphoma
09/2004
1Pancytopenia
11/2003
1Rheumatoid Arthritis
11/2003
1Aplastic Anemia (Anemia, Hypoplastic)
11/2003
1Sepsis (Septicemia)
11/2003

Drug/Important Bio-Agent (IBA)

15IronIBA
01/2023 - 12/2007
2Ferritins (Ferritin)IBA
01/2023 - 11/2016
1Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA
11/2023
1JNJ-64619178IBA
11/2023
1RNA Splicing FactorsIBA
11/2023
1EnzymesIBA
06/2023
1Transferrin (beta 2 Transferrin)IBA
01/2023
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2021
1eculizumabFDA Link
04/2018
1BilirubinIBA
04/2018
1Complement System Proteins (Complement)IBA
04/2018
1HaptoglobinsIBA
04/2018
1Inositol (Myoinositol)IBA
04/2018
1Antifungal AgentsIBA
01/2018
1ibrutinibIBA
01/2018
1Antiviral Agents (Antivirals)IBA
01/2018
1ErythropoietinFDA Link
12/2017
1Azacitidine (5 Azacytidine)FDA Link
11/2016
1HematinicsIBA
01/2016
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
12/2013
1Lenalidomide (CC 5013)FDA Link
02/2013
1Thalidomide (Thalomid)FDA Link
02/2013
1Immunomodulating AgentsIBA
02/2013
1Inosine Triphosphate (ITP)IBA
01/2012
1DeferasiroxFDA Link
12/2010
1Protease Inhibitors (Protease Inhibitor)IBA
04/2010
1Neoplasm Antigens (Tumor Antigens)IBA
06/2005
1AntigensIBA
06/2005
1DNA (Deoxyribonucleic Acid)IBA
12/2004
1Etanercept (Enbrel)FDA Link
11/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2003

Therapy/Procedure

14Chelation Therapy (Therapy, Chelation)
12/2022 - 12/2007
6Erythrocyte Transfusion
01/2023 - 01/2010
4Therapeutics
05/2015 - 09/2004
4Highly Active Antiretroviral Therapy (HAART)
01/2012 - 09/2004
2Induction Chemotherapy
06/2023 - 04/2009
2Stem Cell Transplantation
01/2018 - 01/2011
1Communication Aids for Disabled (TDD)
01/2023
1Hematopoietic Stem Cell Transplantation
05/2017
1Activities of Daily Living (ADL)
01/2016
1Drug Therapy (Chemotherapy)
04/2010
1Salvage Therapy
08/2008
1Combination Drug Therapy (Combination Chemotherapy)
09/2004