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Axel Kramer Selected Research

polihexanide

1/2023Comparison of antibiofilm activity of low-concentrated hypochlorites vs polyhexanide-containing antiseptic.
1/2020Poly (hexamethylene biguanide), adsorbed onto Ti-Al-V alloys, kills slime-producing Staphylococci and Pseudomonas aeruginosa without inhibiting SaOs-2 cell differentiation.
4/2019Re-evaluation of polihexanide use in wound antisepsis in order to clarify ambiguities of two animal studies.
10/2018Efficiency of Emulsified Particle-Associated Polyhexamethylenbiguanid-Hydrochlorid (Polihexanide) for Peritoneal Lavage in a Murine Sepsis Model.
2/2018Evaluation of three experimental in vitro models for the assessment of the mechanical cleansing efficacy of wound irrigation solutions.
1/2018Consensus on Wound Antisepsis: Update 2018.
6/2017Viability of Lucilia sericata maggots after exposure to wound antiseptics.
1/2017Proposed phase 2/ step 2 in-vitro test on basis of EN 14561 for standardised testing of the wound antiseptics PVP-iodine, chlorhexidine digluconate, polihexanide and octenidine dihydrochloride.
5/2013Bacterial growth kinetics under a novel flexible methacrylate dressing serving as a drug delivery vehicle for antiseptics.

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Axel Kramer Research Topics

Disease

35Wounds and Injuries (Trauma)
03/2024 - 06/2004
28Infections
03/2024 - 11/2008
12Neoplasms (Cancer)
02/2023 - 10/2012
5Cross Infection (Nosocomial Infection)
01/2021 - 10/2004
5Osteosarcoma (Osteogenic Sarcoma)
07/2020 - 11/2016
5Goiter
03/2013 - 03/2008
4Surgical Wound
12/2020 - 09/2010
4Surgical Wound Infection
07/2017 - 09/2010
3COVID-19
04/2023 - 01/2020
3Hypersensitivity (Allergy)
12/2016 - 09/2010
3Inflammation (Inflammations)
03/2011 - 12/2002
2Stomatitis
02/2023 - 01/2023
2Peritonitis
06/2021 - 10/2018
2Reinfection
01/2021 - 05/2019
2Sepsis (Septicemia)
12/2020 - 10/2018
2Pneumonia (Pneumonitis)
12/2020 - 01/2011
2Wound Infection (Wound Infections)
12/2020 - 11/2008
2Bites and Stings (Sting)
01/2018 - 09/2010
2Leg Ulcer
05/2015 - 01/2011
2Cataract (Cataracts)
10/2013 - 06/2007
1Mucositis
01/2023
1Gingivitis
01/2022
1Periodontitis
01/2022
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2022
1Diverticulitis
06/2021
1Anastomotic Leak
06/2021
1Skin Diseases (Skin Disease)
03/2021
1Fatigue
01/2021
1Headache (Headaches)
01/2021
1Community-Acquired Infections
12/2020
1Liver Abscess
12/2020
1Suppuration
12/2020
1Prostatic Neoplasms (Prostate Cancer)
01/2019

Drug/Important Bio-Agent (IBA)

21Local Anti-Infective Agents (Antiseptics)IBA
02/2023 - 01/2005
17Anti-Bacterial Agents (Antibiotics)IBA
03/2024 - 06/2004
9polihexanideIBA
01/2023 - 05/2013
7Povidone-Iodine (Betadine)FDA LinkGeneric
01/2018 - 03/2006
6IodineIBA
10/2013 - 03/2006
5SolutionsIBA
03/2024 - 01/2018
5octenidineIBA
01/2023 - 05/2013
4chlorhexidine gluconate (Dyna-Hex)FDA LinkGeneric
01/2019 - 10/2004
4thiamine triphosphorate (TTP)IBA
01/2016 - 03/2011
3Hypochlorous Acid (Hypochlorite)IBA
01/2023 - 01/2018
3Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
03/2013 - 03/2006
2MouthwashesIBA
02/2023 - 01/2023
2Ethanol (Ethyl Alcohol)IBA
01/2022 - 09/2010
2ToothpastesIBA
01/2022 - 12/2002
2Methicillin (Metin)FDA Link
12/2020 - 01/2016
2Methylnitronitrosoguanidine (MNNG)IBA
07/2020 - 11/2016
2Anti-Infective Agents (Microbicides)IBA
01/2020 - 01/2018
2Biocompatible Materials (Biomaterials)IBA
01/2020 - 01/2011
2Disinfectants (Biocides)IBA
01/2020 - 01/2013
2dexpanthenol (panthenol)FDA Link
01/2019 - 01/2016
2ChemokinesIBA
01/2019 - 01/2017
2CytokinesIBA
01/2019 - 01/2017
2phenoxyethanol (2-phenoxyethanol)IBA
01/2018 - 05/2013
2SuspensionsIBA
01/2017 - 01/2016
2Oxygen (Dioxygen)IBA
01/2015 - 03/2011
2Plasma GasesIBA
01/2015 - 01/2014
1Artificial SalivaIBA
03/2024
1AlbuminsIBA
03/2024
1MucinsIBA
03/2024
1Sodium ChlorideFDA LinkGeneric
03/2024
1Chewing Gum (Chewing Gums)IBA
01/2022
12-Propanol (Isopropyl Alcohol)FDA LinkGeneric
01/2022
11-Propanol (Propanol)IBA
01/2022
1SugarsIBA
01/2022
1Nasal SpraysIBA
01/2022
1Ceftriaxone (Ceftriaxon)FDA LinkGeneric
06/2021
1Volatile Organic CompoundsIBA
01/2021
1SmokeIBA
01/2020
1Rifampin (Rifampicin)FDA LinkGeneric
05/2019
1FluoroquinolonesIBA
05/2019
1mesoglycanIBA
02/2019
1InterleukinsIBA
01/2019
1AllantoinIBA
01/2019
1matrigelIBA
01/2019
1MicroRNAs (MicroRNA)IBA
01/2019
1AndrogensIBA
01/2019
1sodium thiocyanateIBA
01/2019

Therapy/Procedure

20Therapeutics
09/2021 - 06/2004
5Drug Therapy (Chemotherapy)
02/2023 - 01/2011
4Hand Hygiene
01/2020 - 10/2004
4Debridement
06/2017 - 11/2008
3Operative Surgical Procedures
05/2019 - 01/2011
3Punctures
01/2018 - 03/2011
3Negative-Pressure Wound Therapy
07/2017 - 08/2010
2Radiotherapy
02/2023 - 01/2023
2Oral Hygiene (Dental Hygiene)
01/2023 - 01/2014
2Arthroplasty
01/2022 - 05/2019
2Sutures (Suture)
12/2014 - 09/2010
2Catheters
01/2013 - 01/2011
2Contact Lenses
10/2012 - 11/2010
2Critical Care (Surgical Intensive Care)
01/2011 - 09/2010
1Long-Term Care
04/2023
1Pain Management
02/2023
1Pancreaticoduodenectomy
02/2022
1Prostheses and Implants (Prosthesis)
01/2022
1Home Care Dental Devices (Dental Floss)
01/2022
1Internal Fracture Fixation
05/2019