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Gideon Koren Selected Research

Doxylamine

11/2016Demonstration of early efficacy results of the delayed-release combination of doxylamine-pyridoxine for the treatment of nausea and vomiting of pregnancy.
1/2016Effectiveness of doxylamine-pyridoxine for morning sickness.
3/2015Maternal safety of the delayed-release doxylamine and pyridoxine combination for nausea and vomiting of pregnancy; a randomized placebo controlled trial.
2/2015Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial.
12/2014Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs.
12/2014Treating morning sickness in the United States--changes in prescribing are needed.
6/2014The delayed-release combination of doxylamine and pyridoxine (Diclegis®/Diclectin ®) for the treatment of nausea and vomiting of pregnancy.
3/2013Comparing the pharmacokinetics of doxylamine/pyridoxine delayed-release combination in nonpregnant women of reproductive age and women in the first trimester of pregnancy.
1/2013The return to the USA of doxylamine-pyridoxine delayed release combination (Diclegis®) for morning sickness--a new morning for American women.
10/2012Motherisk update. Is ondansetron safe for use during pregnancy?
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Gideon Koren Research Topics

Disease

35Spontaneous Abortion (Miscarriage)
01/2022 - 01/2002
34Pain (Aches)
12/2020 - 09/2002
34Neural Tube Defects (Exencephaly)
01/2020 - 01/2002
31Neoplasms (Cancer)
01/2020 - 01/2002
31Nausea
08/2018 - 05/2002
30Vomiting
08/2018 - 05/2002
27Fetal Alcohol Spectrum Disorders
01/2021 - 01/2003
24Birth Weight (Birth Weights)
12/2016 - 08/2002
18Infections
01/2022 - 04/2004
17Congenital Abnormalities (Deformity)
05/2015 - 11/2005
14Hypertension (High Blood Pressure)
05/2019 - 07/2003
13Epilepsy (Aura)
10/2015 - 01/2004
12Stillbirth
01/2017 - 11/2003
11Morning Sickness
01/2016 - 08/2004
11Poisoning
09/2015 - 06/2003
10Long QT Syndrome
01/2020 - 07/2003
9Premature Birth (Birth, Premature)
01/2021 - 08/2006
9Hypersensitivity (Allergy)
01/2017 - 09/2006
9Gestational Diabetes (Gestational Diabetes Mellitus)
03/2015 - 01/2003
8Wounds and Injuries (Trauma)
01/2019 - 09/2002
7Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
03/2021 - 07/2007
7Asthma (Bronchial Asthma)
06/2018 - 12/2009
7Mental Disorders (Mental Disorder)
07/2017 - 04/2005
7Drug-Related Side Effects and Adverse Reactions
02/2015 - 06/2006
7Hemorrhage
02/2015 - 11/2005
7Body Weight (Weight, Body)
04/2012 - 01/2002
6Cardiac Arrhythmias (Arrythmia)
01/2022 - 02/2011
6Autism Spectrum Disorder
01/2021 - 01/2018
6Pregnancy Complications
01/2021 - 02/2003
6Obesity
01/2019 - 01/2002
6Pre-Eclampsia (Preeclampsia)
11/2016 - 08/2002
6Seizures (Absence Seizure)
11/2011 - 01/2003
5Ventricular Tachycardia
01/2021 - 12/2008
5Perinatal Death
01/2019 - 02/2003
5Pulmonary Hypertension
03/2018 - 06/2009
5Neonatal Abstinence Syndrome
06/2015 - 04/2006
5Breast Neoplasms (Breast Cancer)
09/2011 - 06/2007
5Hypoglycemia (Reactive Hypoglycemia)
01/2011 - 08/2005
4Sickle Cell Anemia (Hemoglobin S Disease)
01/2021 - 03/2004
4Familial Mediterranean Fever (Periodic Disease)
01/2020 - 08/2003
4Type 2 Diabetes Mellitus (MODY)
12/2019 - 09/2007
4Diabetes Mellitus
12/2019 - 03/2014
4Anemia
11/2019 - 10/2002
4Substance-Related Disorders (Drug Abuse)
01/2019 - 02/2007
4Hypothyroidism
12/2018 - 06/2005

Drug/Important Bio-Agent (IBA)

53Pharmaceutical PreparationsIBA
03/2021 - 01/2002
34Folic Acid (Vitamin M)FDA LinkGeneric
01/2020 - 01/2002
20Antidepressive Agents (Antidepressants)IBA
11/2019 - 11/2004
17Biomarkers (Surrogate Marker)IBA
01/2020 - 09/2002
16Opioid Analgesics (Opioids)IBA
01/2019 - 04/2002
16Pyridoxine (Pyridoxin)FDA LinkGeneric
11/2016 - 05/2002
16DoxylamineIBA
11/2016 - 05/2002
15Hydrocortisone (Cortisol)FDA LinkGeneric
06/2018 - 06/2009
13Codeine (Codeine Phosphate)FDA LinkGeneric
01/2019 - 08/2006
11Morphine (MS Contin)FDA LinkGeneric
01/2017 - 01/2004
11Analgesics (Analgesic Drugs)IBA
09/2015 - 03/2003
10Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2003
10Anticonvulsants (Antiepileptic Drugs)IBA
02/2019 - 01/2004
10pyridoxine drug combination doxylamine dicyclomine (bendectin)FDA Link
03/2015 - 05/2002
9Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
02/2019 - 06/2009
9Adrenal Cortex Hormones (Corticosteroids)IBA
06/2018 - 01/2005
8Fatty Acids (Saturated Fatty Acids)IBA
04/2015 - 01/2006
8Glyburide (Glibenclamide)FDA LinkGeneric
03/2015 - 01/2003
8Methotrexate (Mexate)FDA LinkGeneric
05/2014 - 05/2003
8IfosfamideFDA LinkGeneric
01/2012 - 03/2004
8EstersIBA
11/2010 - 01/2005
7IronIBA
11/2019 - 06/2003
7Ethanol (Ethyl Alcohol)IBA
11/2019 - 06/2004
7Acetaminophen (Paracetamol)FDA LinkGeneric
10/2015 - 01/2004
7TeratogensIBA
01/2014 - 04/2004
7Carbamazepine (Tegretol)FDA LinkGeneric
01/2013 - 05/2004
7Valproic Acid (Depakote)FDA LinkGeneric
02/2012 - 10/2002
6AntiemeticsIBA
01/2020 - 05/2002
6Hypoglycemic Agents (Hypoglycemics)IBA
02/2019 - 07/2006
6Antipsychotic Agents (Antipsychotics)IBA
02/2019 - 01/2002
6AntioxidantsIBA
01/2018 - 01/2003
6Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2015 - 12/2002
6TabletsIBA
03/2015 - 07/2003
6Folic Acid AntagonistsIBA
04/2012 - 05/2004
5Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022 - 10/2008
5Methylphenidate (Ritalin)FDA LinkGeneric
03/2021 - 07/2007
5PotassiumIBA
01/2021 - 07/2004
5Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2019 - 09/2007
5EnzymesIBA
11/2016 - 06/2006
5Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2015 - 08/2009
5Ondansetron (Zofran)FDA LinkGeneric
02/2015 - 09/2004
5Nitrofurantoin (Macrodantin)FDA LinkGeneric
02/2015 - 02/2007
5Acyclovir (Aciclovir)FDA LinkGeneric
03/2012 - 05/2006
5VaccinesIBA
07/2011 - 09/2004
5Tetracaine (Amethocaine)FDA LinkGeneric
12/2009 - 04/2002
4Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 11/2011
4Hormones (Hormone)IBA
01/2020 - 09/2002
4ColchicineFDA LinkGeneric
01/2020 - 08/2003
4Glucose (Dextrose)FDA LinkGeneric
12/2019 - 07/2007
4Biological ProductsIBA
01/2019 - 06/2009

Therapy/Procedure

35Therapeutics
11/2020 - 05/2002
21Drug Therapy (Chemotherapy)
01/2020 - 05/2002
14Therapeutic Abortion
04/2013 - 01/2002
5Analgesia
01/2016 - 06/2006
5Cesarean Section (Caesarean Section)
01/2013 - 06/2009