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Lars Klareskog Selected Research

Rheumatoid Arthritis

1/2016	Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.
10/2015	Interactions between amino acid-defined major histocompatibility complex class II variants and smoking in seropositive rheumatoid arthritis.
9/2015	Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.
5/2015	Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study.
5/2015	Associations with smoking and shared epitope differ between IgA- and IgG-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis.
5/2015	Autoimmunity: lungs and citrullination.
5/2015	Gene-gene interaction and RNA splicing profiles of MAP2K4 gene in rheumatoid arthritis.
3/2015	Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles.
3/2015	High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
2/2015	Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.

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Lars Klareskog Research Topics

Disease

110	Rheumatoid Arthritis 01/2016 - 08/2003
24	Arthritis (Polyarthritis) 01/2016 - 01/2002
13	Inflammation 11/2014 - 01/2004
6	Autoimmune Diseases (Autoimmune Disease) 01/2016 - 09/2008
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 06/2013 - 09/2003
3	Rheumatic Diseases (Rheumatism) 07/2012 - 02/2004
3	Multiple Sclerosis 12/2009 - 05/2005
3	Experimental Arthritis 06/2009 - 01/2005
3	Lymphoma (Lymphomas) 03/2006 - 06/2003
2	Pain (Aches) 01/2015 - 08/2014
2	Synovitis 08/2013 - 01/2006
2	Joint Diseases (Joint Disease) 05/2012 - 11/2010
2	Necrosis 01/2010 - 01/2006
2	Myasthenia Gravis 11/2009 - 09/2008
2	Infection 10/2007 - 01/2004
2	Tetanus 04/2007 - 01/2007
2	Celiac Disease (Celiac Sprue) 02/2005 - 06/2002
1	Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis) 01/2016
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2016
1	Osteoarthritis 01/2016
1	Periodontitis 07/2014
1	Osteitis 08/2013
1	Arthralgia (Joint Pain) 07/2013
1	Venous Thrombosis (Deep-Vein Thrombosis) 06/2013
1	Vascular Diseases (Vascular Disease) 06/2013
1	Bone Resorption 05/2012
1	Metabolic Bone Diseases (Osteopenia) 05/2012
1	Metrorrhagia (Spotting) 01/2012
1	Heart Block 12/2010
1	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2010

Drug/Important Bio-Agent (IBA)

36	AntibodiesIBA 09/2015 - 06/2002
23	Proteins (Proteins, Gene)IBA 05/2015 - 12/2004
17	AutoantibodiesIBA 03/2015 - 01/2004
14	AntigensIBA 09/2015 - 01/2004
14	HLA-DRB1 antigen (HLA DRB1)IBA 05/2015 - 01/2004
13	PeptidesIBA 05/2015 - 01/2008
12	acetyl 4-aminosalicylic acidIBA 05/2015 - 01/2009
9	Methotrexate (Mexate)FDA LinkGeneric 08/2013 - 02/2004
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011 - 09/2003
8	Immunoglobulin G (IgG)IBA 01/2016 - 06/2002
8	CitrullineIBA 03/2015 - 01/2005
7	TNFR-Fc fusion protein (etanercept)FDA Link 11/2009 - 02/2004
6	Collagen Type II (Type II Collagen)IBA 07/2013 - 01/2005
6	infliximab (Remicade)FDA Link 01/2010 - 01/2005
5	Carbon MonoxideIBA 01/2016 - 02/2004
5	Rheumatoid FactorIBA 11/2013 - 06/2004
4	Immunoglobulin A (IgA)IBA 05/2015 - 06/2002
4	Fibrinogen (Factor I)FDA Link 01/2015 - 05/2010
4	Biological Markers (Surrogate Marker)IBA 07/2013 - 01/2010
4	HLA-DR Antigens (HLA-DR)IBA 03/2013 - 10/2004
4	cyclic citrullinated peptideIBA 01/2012 - 01/2004
4	AutoantigensIBA 01/2006 - 01/2002
3	TNF Receptor-Associated Factor 1IBA 02/2011 - 09/2007
3	DNA (Deoxyribonucleic Acid)IBA 01/2010 - 01/2004
3	ORALIT (ORS)IBA 11/2009 - 03/2006
2	Amino Acids FDA Link 10/2015 - 03/2012
2	Prednisolone (Predate)FDA LinkGeneric 01/2015 - 01/2004
2	ametantrone (HAQ)IBA 01/2015 - 08/2014
2	Silicon Dioxide (Sand)FDA LinkGeneric 03/2014 - 06/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2013 - 01/2007
2	Phosphopyruvate Hydratase (Enolase)IBA 05/2013 - 12/2009
2	VimentinIBA 05/2013 - 01/2008
2	Mineral Oil (Liquid Paraffin)FDA LinkGeneric 01/2012 - 01/2005
2	prostaglandin-E synthaseIBA 08/2011 - 11/2005
2	SmokeIBA 03/2011 - 01/2011
2	EpitopesIBA 12/2010 - 01/2005
2	CytokinesIBA 07/2010 - 12/2005
2	golimumab FDA Link 06/2010 - 01/2010
2	Interferon-gamma (Interferon, gamma)IBA 12/2009 - 05/2005
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 09/2007 - 09/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2006 - 02/2004
2	triamcinolone hexacetonide (Aristospan)FDA Link 05/2006 - 12/2005
2	OilsIBA 01/2005 - 01/2002
2	Lipoproteins (Lipoprotein)IBA 01/2005 - 09/2003
2	GoldIBA 08/2003 - 01/2002
1	HormonesIBA 05/2015
1	Nicotine FDA Link 10/2014
1	abatacept (BELATACEPT)FDA Link 08/2013
1	Antirheumatic Agents (DMARD)IBA 07/2013
1	Antiphospholipid AntibodiesIBA 06/2013
1	HLA-DRB1*04IBA 06/2013
1	Tyrosine (L-Tyrosine)FDA Link 01/2013
1	HLA-A Antigens (HLA-A)IBA 03/2012
1	HLA-DQB1 antigen (HLA DQB1)IBA 03/2012
1	HLA-DQA1 (HLA DQA1)IBA 03/2012
1	HLA-B Antigens (HLA-B)IBA 03/2012
1	HLA-DPB1 (HLA DPB1)IBA 03/2012
1	HLA-C Antigens (HLA-C)IBA 03/2012
1	HLA-DPA1 (HLA DPA1)IBA 03/2012
1	CosmeticsIBA 01/2012
1	protein-arginine deiminaseIBA 01/2012
1	Anti-Idiotypic AntibodiesIBA 01/2012
1	Prostaglandins E (PGE)IBA 08/2011
1	Aminocaproic Acids (EAC)FDA LinkGeneric 08/2011
1	HLA-DRB1*0405 antigenIBA 01/2011
1	Complement System Proteins (Complement)IBA 01/2011
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2011
1	glutathione S-transferase T1IBA 11/2010

Therapy/Procedure

2	Aftercare (After-Treatment) 01/2010 - 10/2006
1	Skin Care 01/2012