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David Kipling Selected Research

SB 203580

1/2016The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells.
1/2013The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome.
12/2011Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors.
6/2010Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome.
6/2010Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts.
4/2007The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.
5/2006Prevention of accelerated cell aging in the Werner syndrome.
11/2005Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor.

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David Kipling Research Topics

Disease

19Werner Syndrome (Werner's Syndrome)
04/2016 - 04/2003
14Neoplasms (Cancer)
01/2023 - 05/2003
3Melanoma (Melanoma, Malignant)
01/2023 - 05/2003
3Genomic Instability
02/2013 - 04/2007
2Communicable Diseases (Infectious Diseases)
01/2023 - 12/2011
2Inflammation (Inflammations)
01/2020 - 10/2009
2Wounds and Injuries (Trauma)
03/2018 - 02/2003
2Carcinogenesis
01/2018 - 01/2004
2Human Influenza (Influenza)
06/2015 - 01/2012
2Liposarcoma
01/2014 - 03/2010
2Progeria (Hutchinson Gilford Syndrome)
02/2013 - 04/2004
1Autoimmune Diseases (Autoimmune Disease)
01/2023
1Acute Disease
01/2022
1COVID-19
01/2022
1Parasitic Diseases (Parasitic Disease)
01/2020
1Hyperplasia
01/2020
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2018
1Monoclonal Gammopathy of Undetermined Significance
06/2015
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
06/2015
1Nijmegen Breakage Syndrome
02/2015
1Seasonal Allergic Rhinitis (Hay Fever)
09/2014
1Allergic Rhinitis
09/2014
1Rothmund-Thomson Syndrome (Syndrome, Rothmund-Thomson)
10/2013
1Pneumococcal Pneumonia
12/2011
1Lung Diseases (Lung Disease)
12/2011
1Sarcoma (Soft Tissue Sarcoma)
03/2010
1Lung Neoplasms (Lung Cancer)
01/2010
1Breast Neoplasms (Breast Cancer)
01/2010
1Vascular Calcification
10/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
06/2009
1Infections
02/2009
1Insulin Resistance
01/2008

Drug/Important Bio-Agent (IBA)

13p38 Mitogen-Activated Protein KinasesIBA
04/2016 - 11/2005
8SB 203580IBA
01/2016 - 11/2005
7Telomerase (Telomerase Reverse Transcriptase)IBA
03/2006 - 02/2003
5Proteins (Proteins, Gene)FDA Link
06/2018 - 05/2003
5Phosphotransferases (Kinase)IBA
12/2011 - 04/2007
45- amino- 1- (4- fluorophenyl)- 4- (3- (2,3- dihydroxypropoxy)benzoyl)pyrazoleIBA
01/2016 - 07/2008
3AntibodiesIBA
01/2023 - 01/2020
3Immunoglobulin E (IgE)IBA
01/2020 - 09/2014
3KetonesIBA
01/2016 - 07/2008
3DNA (Deoxyribonucleic Acid)IBA
08/2013 - 04/2003
3VX-745IBA
09/2010 - 11/2009
3Cyclin-Dependent Kinase Inhibitor p16IBA
01/2004 - 05/2003
2Immunoglobulin G (IgG)IBA
01/2022 - 06/2015
2MAP-kinase-activated kinase 2IBA
06/2015 - 01/2013
2Immunoglobulins (Immunoglobulin)IBA
06/2015 - 06/2015
2Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
09/2014 - 08/2013
2VaccinesIBA
12/2011 - 02/2009
2doramapimodIBA
06/2010 - 11/2006
1AntigensIBA
01/2023
1Complementarity Determining Regions (Complementarity Determining Region)IBA
01/2023
1AutoantigensIBA
01/2023
1Yellow Fever Vaccine (Vaccine, Yellow Fever)FDA Link
01/2022
1IgE Receptors (Fc epsilon RI)IBA
01/2018
1BromidesIBA
06/2015
12-chloroquinolineIBA
06/2015
1AcidsIBA
06/2015
13-pyridinylboronic acidIBA
06/2015
1ParaproteinsIBA
06/2015
1Immunoglobulin A (IgA)IBA
06/2015
1Actins (F Actin)IBA
02/2015
1GalactosidasesIBA
02/2015
1Cysteine Dioxygenase (Dioxygenase, Cysteine)IBA
01/2014
1Messenger RNA (mRNA)IBA
01/2014
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
08/2013
1A-Form DNA (A-DNA)IBA
02/2013
1Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA
01/2012
1Adenosine Triphosphate (ATP)IBA
09/2010
1Reactive Oxygen Species (Oxygen Radicals)IBA
06/2010
1IfosfamideFDA LinkGeneric
03/2010
1Doxorubicin (Adriamycin)FDA LinkGeneric
03/2010
1Therapeutic UsesIBA
02/2010
1Fatty Acids (Saturated Fatty Acids)IBA
01/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2009
1Interleukin-8 (Interleukin 8)IBA
10/2009
1CalciumIBA
01/2008
1Phosphates (Orthophosphate)IBA
01/2008
1VX (EDIM)IBA
09/2007
1pyrazoleIBA
11/2006
1CarbamatesIBA
11/2006
1Urea (Carbamide)FDA LinkGeneric
11/2006
1Mitogen-Activated Protein Kinase 14IBA
11/2006
1CytokinesIBA
11/2005
1Small Interfering RNA (siRNA)IBA
01/2004
1Growth InhibitorsIBA
05/2003
1beta-Galactosidase (Lactaid)IBA
02/2003

Therapy/Procedure

5Therapeutics
06/2018 - 02/2003
1Drug Therapy (Chemotherapy)
06/2018
1Radiotherapy
06/2018