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Jiri Kassa Selected Research

Sarin

3/2015A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.
11/2012A comparison of the potency of a novel bispyridinium oxime K203 and currently available oximes (obidoxime, HI-6) to counteract the acute neurotoxicity of sarin in rats.
5/2012The benefit of combination of oximes for the neuroprotective efficacy of antidotal treatment of sarin-poisoned rats.
7/2011The benefit of combinations of oximes for the reactivating and therapeutic efficacy of antidotal treatment of sarin poisoning in rats and mice.
9/2006The reactivating and therapeutic efficacy of oximes to counteract Russian VX poisonings.
7/2005Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain.

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Jiri Kassa Research Topics

Disease

43Poisoning
04/2015 - 07/2005
2Alzheimer Disease (Alzheimer's Disease)
11/2015 - 10/2008
1Neurodegenerative Diseases (Neurodegenerative Disease)
06/2014
1Neurobehavioral Manifestations
10/2008
1Dislocations
01/2007

Drug/Important Bio-Agent (IBA)

34OximesIBA
04/2015 - 07/2005
22tabunIBA
04/2015 - 12/2006
18HI 6 (H16)IBA
03/2015 - 07/2005
10Obidoxime Chloride (Obidoxime)IBA
09/2013 - 01/2007
9Atropine (Hyoscyamine)FDA LinkGeneric
09/2013 - 01/2007
9SomanIBA
07/2011 - 09/2006
8Trimedoxime (Trimedoxime Bromide)IBA
04/2015 - 09/2007
7AcetylcholinesteraseIBA
03/2015 - 01/2007
7cyclohexyl methylphosphonofluoridate (cyclosarin)IBA
06/2009 - 09/2006
6SarinIBA
03/2015 - 07/2005
3VX (EDIM)IBA
08/2013 - 09/2006
2Tacrine (Cognex)FDA Link
11/2015 - 10/2008
2Transcription Factors (Transcription Factor)IBA
05/2009 - 01/2007
16- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA
11/2015
1Cholinergic ReceptorsIBA
06/2014
1p38 Mitogen-Activated Protein KinasesIBA
05/2009
1Cholinesterase ReactivatorsIBA
10/2008
17-methoxytacrine (TA 03)IBA
10/2008
1Glutathione PeroxidaseIBA
01/2008
1Malathion (Karbofos)FDA LinkGeneric
01/2008
1Glutathione Reductase (Glutathione-Disulfide Reductase)IBA
01/2008
1Glutathione (Reduced Glutathione)IBA
01/2008
1Protein Kinases (Protein Kinase)IBA
01/2007
1BenactyzineIBA
12/2006
1panpalIBA
12/2006
1Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric
12/2006
1S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolateIBA
09/2006