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Petros C Karakousis Selected Research

Thioridazine (Mellaril)

12/2014Thioridazine for treatment of tuberculosis: promises and pitfalls.
9/2014Sterilizing activity of thioridazine in combination with the first-line regimen against acute murine tuberculosis.
7/2014Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.
6/2013Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis.
5/2011New patentable use of an old neuroleptic compound thioridazine to combat tuberculosis: a gene regulation perspective.

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Petros C Karakousis Research Topics

Disease

33Tuberculosis (Tuberculoses)
07/2015 - 09/2004
30Infection
05/2015 - 09/2004
10Granuloma
01/2015 - 09/2004
5Anoxia (Hypoxia)
07/2014 - 02/2008
3Latent Tuberculosis
12/2014 - 01/2013
3Body Weight (Weight, Body)
07/2014 - 07/2012
3Acquired Immunodeficiency Syndrome (AIDS)
01/2012 - 09/2004
2Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
08/2013 - 06/2013
2Inflammation
01/2013 - 01/2013
2HIV Infections (HIV Infection)
01/2012 - 09/2004
1Communicable Diseases (Infectious Diseases)
07/2015
1Bacterial Infections (Bacterial Infection)
09/2014
1Retinal Detachment (Retinal Detachments)
12/2012
1Ischemia
01/2011
1Starvation
10/2009
1Uveitis
10/2008
1Fever (Fevers)
06/2006
1Endocarditis
06/2006
1Heart Diseases (Heart Disease)
06/2006
1Heart Valve Diseases (Valvular Heart Disease)
06/2006
1Q Fever (Fever, Q)
06/2006
1Cellulitis
01/2003

Drug/Important Bio-Agent (IBA)

14Isoniazid (Ftivazide)FDA LinkGeneric
01/2015 - 09/2004
12Rifampin (Rifampicin)FDA LinkGeneric
01/2015 - 09/2004
8butyl 3-(1H-tetrazol-5-yl)oxanilate (MTB)IBA
05/2015 - 09/2004
7PyrazinamideFDA LinkGeneric
08/2013 - 09/2009
5Thioridazine (Mellaril)FDA LinkGeneric
12/2014 - 05/2011
4CytokinesIBA
07/2014 - 11/2010
4Anti-Bacterial Agents (Antibiotics)IBA
05/2013 - 04/2011
3Interferon-gamma (Interferon, gamma)IBA
09/2014 - 09/2004
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2014 - 11/2010
3rifapentine (Priftin)FDA Link
03/2013 - 07/2012
2ChemokinesIBA
01/2013 - 07/2012
2RifamycinsIBA
12/2012 - 07/2012
2pimonidazoleIBA
01/2011 - 07/2008
1MicroRNAs (MicroRNA)IBA
07/2015
1Biological Markers (Surrogate Marker)IBA
01/2015
1exopolyphosphataseIBA
01/2015
1PA 824IBA
12/2014
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
09/2014
1Simvastatin (Zocor)FDA LinkGeneric
09/2014
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
08/2014
1Matrix MetalloproteinasesIBA
07/2014
1Neutralizing AntibodiesIBA
07/2014
1rifamycin SVIBA
08/2013
1Drug CombinationsIBA
08/2013
1N-Formylmethionine Leucyl-PhenylalanineIBA
01/2013
1TB meningitisIBA
01/2013
1Protein Subunits (Protein Subunit)IBA
01/2013
1FluoroquinolonesIBA
12/2012
1Erythromycin (Erycette)FDA LinkGeneric
12/2012
1prothrombin complex concentrates (PPSB)IBA
12/2012
1Ethambutol (Myambutol)FDA LinkGeneric
08/2012
15-(6)-carboxyfluorescein diacetate succinimidyl ester (CFSE)IBA
07/2012
1Carbon MonoxideIBA
01/2012
1Virulence Factors (Pathogenicity Factors)IBA
09/2011
1Adenosine Triphosphate (ATP)IBA
07/2011
1phenothiazineIBA
05/2011
1OxygenIBA
01/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2011
1Streptomycin (Streptomycin Sulfate)FDA Link
10/2010
1DNA (Deoxyribonucleic Acid)IBA
09/2009
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2009
1tebufenozide (Mimic)IBA
03/2009
1Dioctyl Sulfosuccinic Acid (DOSS)IBA
03/2009
1Metronidazole (Metric)FDA LinkGeneric
07/2008
1Sigma FactorIBA
01/2008
1Acute Q feverIBA
06/2006
1I-antigenIBA
06/2006
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2003

Therapy/Procedure

3Drug Therapy (Chemotherapy)
07/2012 - 09/2004
3Highly Active Antiretroviral Therapy (HAART)
01/2011 - 09/2004
1Intramuscular Injections
10/2010