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Hagop Kantarjian Selected Research

homoharringtonine

1/2015Effectiveness of homoharringtonine (omacetaxine mepesuccinate) for treatment of acute myeloid leukemia: a meta-analysis of Chinese studies.
10/2013Omacetaxine mepesuccinate (synribo) - newly launched in chronic myeloid leukemia.
7/2013Omacetaxine mepesuccinate for patients with accelerated phase chronic myeloid leukemia with resistance or intolerance to two or more tyrosine kinase inhibitors.
12/2009Homoharringtonine, omacetaxine mepesuccinate, and chronic myeloid leukemia circa 2009.
1/2007Phase I/II study of subcutaneous homoharringtonine in patients with chronic myeloid leukemia who have failed prior therapy.

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Hagop Kantarjian Research Topics

Disease

177BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2015 - 02/2002
114Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
09/2015 - 01/2002
81Leukemia
07/2015 - 03/2002
77Myelodysplastic Syndromes (Myelodysplastic Syndrome)
09/2015 - 01/2002
60Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
07/2015 - 03/2002
49Philadelphia Chromosome
11/2015 - 02/2002
45Neoplasms (Cancer)
05/2015 - 01/2002
27Hematologic Neoplasms (Hematological Malignancy)
09/2015 - 01/2002
27B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2015 - 03/2002
26Primary Myelofibrosis (Myelosclerosis)
08/2015 - 09/2002
21Acute Promyelocytic Leukemia
05/2015 - 05/2003
17Thrombocytopenia (Thrombopenia)
04/2015 - 04/2004
16Blast Crisis (Blast Phase)
03/2014 - 10/2002
15Myeloid Leukemia (Leukemia, Myelocytic)
04/2013 - 04/2006
13Anemia
04/2015 - 03/2002
12Infection
11/2015 - 01/2003
12Chromosome Aberrations (Chromosome Abnormalities)
08/2012 - 05/2002
10Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
04/2014 - 06/2002
10Myeloproliferative Disorders (Myeloproliferative Disorder)
02/2008 - 09/2002
9Lymphoma (Lymphomas)
05/2015 - 06/2005
9Polycythemia Vera
08/2013 - 06/2003
9Hypereosinophilic Syndrome (Loeffler Endocarditis)
06/2013 - 09/2002
8Splenomegaly
04/2015 - 03/2002
7Systemic Mastocytosis
09/2013 - 05/2004
7Essential Thrombocythemia
08/2013 - 01/2003
7Multiple Myeloma
08/2011 - 03/2003
6Nausea
07/2015 - 10/2002
5Disease Progression
09/2014 - 11/2006
5Residual Neoplasm
08/2014 - 11/2006
5Fever (Fevers)
08/2013 - 01/2003
5Neutropenia
11/2012 - 09/2003
4Diarrhea
07/2015 - 12/2003
4Anoxia (Hypoxia)
07/2015 - 01/2011
4Burkitt Lymphoma (Burkitt's Lymphoma)
06/2015 - 03/2002
4Pneumonia (Pneumonitis)
11/2012 - 01/2003
4Drug Toxicity (Drug Safety)
06/2011 - 06/2010
3Hypertension (High Blood Pressure)
11/2015 - 01/2011
3Exanthema (Rash)
11/2015 - 06/2009
3Vomiting
01/2015 - 12/2003

Drug/Important Bio-Agent (IBA)

138imatinib (Gleevec)FDA Link
11/2015 - 02/2002
79Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2015 - 03/2003
43Cytarabine (Cytosar-U)FDA LinkGeneric
07/2015 - 03/2002
31dasatinib (BMS 354825)FDA Link
11/2015 - 06/2006
27Phosphotransferases (Kinase)IBA
08/2015 - 12/2003
26decitabine (5-aza-2'-deoxycytidine)FDA Link
07/2015 - 03/2003
224- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)FDA Link
11/2015 - 07/2005
20fludarabineIBA
06/2015 - 03/2003
17rituximab (Mabthera)FDA Link
06/2015 - 11/2003
17Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2015 - 03/2002
16clofarabine (Clolar)FDA Link
07/2015 - 10/2003
16Bcr-Abl tyrosine kinaseIBA
04/2012 - 02/2002
14arsenic trioxide (Trisenox)FDA Link
05/2015 - 05/2003
13InterferonsIBA
10/2015 - 03/2003
13Azacitidine (5 Azacytidine)FDA Link
08/2015 - 05/2005
13Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2015 - 05/2003
12Interferon-alpha (Interferon Alfa)FDA Link
06/2012 - 01/2003
11Vincristine (Oncovin)FDA LinkGeneric
05/2015 - 03/2002
10Dexamethasone (Maxidex)FDA LinkGeneric
05/2015 - 03/2002
10gemtuzumab (gemtuzumab ozogamicin)FDA Link
10/2014 - 01/2002
9Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
05/2015 - 01/2003
9Doxorubicin (Adriamycin)FDA LinkGeneric
05/2015 - 03/2002
9Hemoglobins (Hemoglobin)IBA
10/2014 - 06/2004
8INCB018424IBA
08/2015 - 04/2010
8DNA (Deoxyribonucleic Acid)IBA
10/2014 - 12/2003
7alemtuzumab (Campath)FDA Link
06/2013 - 11/2005
7tipifarnib (R115777)IBA
03/2011 - 10/2002
6L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
08/2015 - 03/2002
6CMC544 (Inotuzumab Ozogamicin)IBA
04/2015 - 06/2013
6Core Binding Factors (Core-Binding Factor)IBA
10/2014 - 12/2008
6fms-Like Tyrosine Kinase 3IBA
07/2014 - 05/2004
6sorafenib (BAY 43-9006)FDA Link
06/2013 - 12/2008
6Methotrexate (Mexate)FDA LinkGeneric
10/2012 - 03/2002
6TransferasesIBA
11/2007 - 03/2003
5lenalidomide (CC 5013)FDA Link
08/2015 - 05/2007
5homoharringtonineIBA
01/2015 - 01/2007
5Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
10/2013 - 07/2002
5ArsenicIBA
08/2013 - 05/2003
5Histone Deacetylase InhibitorsIBA
09/2012 - 08/2006
5Proteasome Endopeptidase Complex (Proteasome)IBA
08/2011 - 05/2004
5Topotecan (Hycamtin)FDA LinkGeneric
05/2007 - 12/2002
4Monoclonal AntibodiesIBA
06/2015 - 09/2004
4romiplostimFDA Link
11/2014 - 01/2010
4ErythropoietinFDA Link
11/2014 - 06/2004
4Proteins (Proteins, Gene)IBA
09/2012 - 02/2007
4Alkylating AgentsIBA
06/2012 - 05/2004
4Farnesyltranstransferase (Farnesyltransferase)IBA
03/2011 - 10/2002
4Messenger RNA (mRNA)IBA
06/2010 - 05/2002
4Cyclosporine (Ciclosporin)FDA LinkGeneric
07/2007 - 03/2003
4laromustine (VNP40101M)IBA
01/2007 - 05/2004
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2004 - 03/2002
3Hydroxyurea (Hydrea)FDA LinkGeneric
10/2015 - 04/2006
3aurora kinase (aurora A kinase)IBA
08/2015 - 12/2011
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
08/2015 - 07/2002

Therapy/Procedure

65Drug Therapy (Chemotherapy)
11/2015 - 03/2002
14Salvage Therapy
09/2015 - 04/2003
13Stem Cell Transplantation
04/2014 - 07/2003
9Hematopoietic Stem Cell Transplantation
08/2014 - 02/2007
7Transplants (Transplant)
05/2015 - 07/2003
4Combination Drug Therapy (Combination Chemotherapy)
06/2015 - 05/2007
3Catheters
01/2015 - 09/2003