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Michael R Jacobs Selected Research

Clavulanic Acid (Potassium Clavulanate)

12/2007Combating resistance: application of the emerging science of pharmacokinetics and pharmacodynamics.
4/2007Antimicrobial resistance in Haemophilus influenzae.
6/2005Extended release amoxicillin/clavulanate: optimizing a product for respiratory infections based on pharmacodynamic principles.
2/2005Efficacy of a new pharmacokinetically enhanced formulation of amoxicillin/clavulanate (2000/125 mg) in adults with community-acquired pneumonia caused by Streptococcus pneumoniae, including penicillin-resistant strains.
8/2004Streptococcus pneumoniae: epidemiology and patterns of resistance.
6/2004Evolution of amoxicillin/clavulanate in the treatment of adults with acute bacterial rhinosinusitis and community-acquired pneumonia in response to antimicrobial-resistance patterns.
8/2003Macrolide resistance: an increasing concern for treatment failure in children.
10/2002Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

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Michael R Jacobs Research Topics

Disease

28Infection
10/2014 - 10/2002
8Respiratory Tract Infections (Respiratory Tract Infection)
12/2007 - 10/2002
7Otitis Media
07/2009 - 08/2002
5Pneumonia (Pneumonitis)
10/2008 - 10/2002
3Pneumococcal Infections
06/2010 - 03/2005
3Sinusitis
08/2003 - 03/2002
2Tuberculosis (Tuberculoses)
09/2015 - 01/2004
2Bacteremia
08/2013 - 10/2008
2Wounds and Injuries (Trauma)
04/2013 - 12/2007
2Gastroparesis
04/2012 - 01/2011
2Neoplasms (Cancer)
04/2012 - 01/2012
2Impetigo
12/2007 - 03/2007
1Hernia (Hernias)
04/2013
1Ventral Hernia
04/2013
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2012
1Cystic Fibrosis (Mucoviscidosis)
04/2011
1Chronic Obstructive Pulmonary Disease (COPD)
04/2011
1Endocarditis
12/2010
1Surgical Wound Infection
10/2010
1Wound Infection (Wound Infections)
10/2010
1Inflammation
11/2009
1Sepsis (Septicemia)
07/2009
1Meningitis
04/2007
1Acne Vulgaris
10/2006
1Cross Infection (Nosocomial Infection)
08/2005
1Staphylococcal Infections
12/2004
1Body Weight (Weight, Body)
12/2004
1Cellulitis
12/2004

Drug/Important Bio-Agent (IBA)

10Amoxicillin (Wymox)FDA LinkGeneric
12/2008 - 10/2002
8Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
12/2007 - 10/2002
8Anti-Bacterial Agents (Antibiotics)IBA
12/2006 - 03/2002
4Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link
03/2007 - 10/2002
4Penicillins (Penicillin)FDA Link
06/2005 - 10/2002
4Anti-Infective Agents (Microbicides)IBA
06/2004 - 01/2003
3Penicillin G (Benzylpenicillin)FDA LinkGeneric
06/2012 - 10/2008
3MacrolidesIBA
12/2008 - 08/2003
3Clindamycin (Cleocin)FDA LinkGeneric
12/2008 - 08/2004
3Ceftriaxone (Ceftriaxon)FDA LinkGeneric
12/2008 - 08/2003
3beta-Lactamases (beta-Lactamase)IBA
04/2007 - 10/2002
2Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric
09/2015 - 12/2008
2DNA (Deoxyribonucleic Acid)IBA
04/2012 - 01/2011
2Domperidone (Domperidon)IBA
04/2012 - 01/2011
2linezolid (Zyvox)FDA Link
04/2011 - 12/2004
2AntigensIBA
12/2010 - 03/2005
2VancomycinFDA LinkGeneric
10/2010 - 12/2004
2ceftobiproleIBA
08/2009 - 09/2008
2Methicillin (Metin)FDA Link
08/2009 - 12/2007
2Ofloxacin (Levofloxacin)FDA LinkGeneric
12/2008 - 10/2002
2Azithromycin (Zithromax)FDA LinkGeneric
12/2008 - 01/2004
2Cephalosporins (Cephalosporin Antibiotics)IBA
04/2007 - 03/2007
2beta-LactamsIBA
03/2007 - 06/2005
2WCK 771IBA
10/2006 - 12/2004
2nadifloxacinIBA
10/2006 - 12/2004
2FluoroquinolonesIBA
08/2004 - 01/2004
2Conjugate VaccinesIBA
02/2004 - 08/2002
2Clarithromycin (Biaxin)FDA LinkGeneric
01/2004 - 10/2002
1SulfamethoxazoleFDA LinkGeneric
09/2015
1Carbapenems (Carbapenem Antibiotics)IBA
10/2014
1CoagulaseIBA
11/2013
1LactamsIBA
08/2013
1cetuximab (Erbitux)FDA Link
01/2012
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
01/2012
1Nitroglycerin (Dynamite)FDA LinkGeneric
04/2011
1Metoclopramide (Reglan)FDA LinkGeneric
01/2011
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
12/2010
1PolymersIBA
10/2010
1T 91825IBA
06/2010
1Panton-Valentine leukocidinIBA
08/2009
1CytokinesIBA
07/2009
1Toll-Like Receptor 2IBA
07/2009
1retapamulinFDA Link
12/2007
1pleuromutilinIBA
12/2007
1Penicillin-Binding Proteins (Penicillin-Binding Protein)IBA
04/2007
1Ampicillin (Omnipen)FDA LinkGeneric
04/2007
1Mupirocin (Bactroban)FDA LinkGeneric
03/2007
1Dicloxacillin (Dycill)FDA LinkGeneric
03/2007
1Erythromycin (Erycette)FDA LinkGeneric
03/2007
1Cephalexin (Cefalexin)FDA LinkGeneric
03/2007
1hydroxide ionIBA
01/2006
1Doxycycline (Vibramycin)FDA LinkGeneric
06/2005
1VaccinesIBA
03/2005
1Proteins (Proteins, Gene)IBA
03/2005
1AntibodiesIBA
03/2005
1trovafloxacinIBA
12/2004
1Reserpine (Serpasil)FDA Link
12/2004
1Arginine (L-Arginine)FDA Link
12/2004
1moxifloxacin (Avelox)FDA Link
12/2004
1sparfloxacin (AT 4140)FDA Link
12/2004
1QuinolonesIBA
01/2004
1Ethambutol (Myambutol)FDA LinkGeneric
01/2004
1Isoniazid (Ftivazide)FDA LinkGeneric
01/2004
1rifamycin SVIBA
01/2004
1PyrazinamideFDA LinkGeneric
01/2004
1Streptomycin (Streptomycin Sulfate)FDA Link
01/2004

Therapy/Procedure

2Drug Therapy (Chemotherapy)
01/2012 - 09/2002
1Long-Term Care
10/2014
1Blood Component Removal (Apheresis)
11/2013
1Catheters
11/2013
1Transplants (Transplant)
04/2013
1Contact Lenses
11/2009