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M Humbert Selected Research

Idiopathic pulmonary hypertension

1/2015Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats.
9/2012Computed tomography findings of pulmonary venoocclusive disease in scleroderma patients presenting with precapillary pulmonary hypertension.
8/2012ACVRL1 germinal mosaic with two mutant alleles in hereditary hemorrhagic telangiectasia associated with pulmonary arterial hypertension.
4/2011Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats.
1/2011Current management approaches to portopulmonary hypertension.
10/2010Association of a KCNA5 gene polymorphism with systemic sclerosis-associated pulmonary arterial hypertension in the European Caucasian population.
6/2010Prognostic factors of acute heart failure in patients with pulmonary arterial hypertension.
6/2010Pulmonary hypertension in patients with chronic myeloproliferative disorders.
3/2010Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: pathophysiology.
1/2010Beyond arterial remodelling: pulmonary venous and cardiac involvement in patients with systemic sclerosis-associated pulmonary arterial hypertension.
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M Humbert Research Topics

Disease

26Pulmonary Hypertension (Ayerza Syndrome)
06/2015 - 10/2000
19Asthma (Bronchial Asthma)
10/2013 - 02/2000
12Systemic Scleroderma (Systemic Sclerosis)
10/2010 - 06/2000
6Inflammation
04/2011 - 08/2003
6Fibrosis (Cirrhosis)
09/2009 - 06/2000
5Neoplasms (Cancer)
01/2015 - 03/2001
5Hypersensitivity (Allergy)
05/2014 - 02/2000
5Heart Failure
06/2010 - 01/2001
5Connective Tissue Diseases (Connective Tissue Disease)
03/2010 - 08/2003
4Pulmonary Embolism
10/2015 - 12/2005
4Interstitial Lung Diseases (Interstitial Lung Disease)
06/2015 - 01/2008
4Pulmonary Veno-Occlusive Disease (Veno Occlusive Disease, Pulmonary)
12/2009 - 01/2006
4Rhinitis
01/2009 - 04/2001
3HIV Infections (HIV Infection)
03/2010 - 01/2009
3Heart Diseases (Heart Disease)
03/2010 - 09/2006
3Thrombosis (Thrombus)
12/2005 - 10/2004
2Hereditary Hemorrhagic Telangiectasia
08/2012 - 08/2001
2Anoxia (Hypoxia)
06/2011 - 10/2002
2Portal Hypertension
01/2011 - 06/2008
2Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)
07/2010 - 01/2009
2Sarcoidosis (Schaumann Disease)
01/2009 - 05/2003
2Infection
06/2008 - 08/2003
2Rare Diseases (Rare Disease)
09/2004 - 04/2004
2Telangiectasis (Telangiectasia)
05/2004 - 09/2002
2Hypothermia
04/2004 - 04/2004
2Churg-Strauss Syndrome (Allergic Angiitis)
02/2004 - 05/2000
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
08/2003 - 05/2003
2Mixed Connective Tissue Disease (MCTD)
05/2003 - 06/2000
2Lung Diseases (Lung Disease)
08/2001 - 10/2000
1Myositis (Idiopathic Inflammatory Myopathies)
06/2015
1Dyspnea (Shortness of Breath)
04/2012
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2012
1Histiocytic Sarcoma
01/2012
1Osteosarcoma (Osteogenic Sarcoma)
01/2012
1Carcinoma (Carcinomatosis)
01/2012
1Right Ventricular Hypertrophy
04/2011
1Cysts
02/2011
1Hemangiosarcoma (Angiosarcoma)
02/2011
1Hypertension (High Blood Pressure)
01/2011
1Pericarditis
11/2010
1Chronic Disease (Chronic Diseases)
06/2010
1Low Cardiac Output
06/2010
1Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
09/2009
1Chest Pain (Chest Pains)
09/2009
1Airway Remodeling
08/2009
1Exanthema (Rash)
08/2009
1Edema
08/2009
1Cardiovascular Diseases (Cardiovascular Disease)
03/2009
1Fatigue
03/2009
1Overweight
03/2009

Drug/Important Bio-Agent (IBA)

39Idiopathic pulmonary hypertensionIBA
01/2015 - 01/2001
11Immunoglobulin E (IgE)IBA
05/2011 - 02/2000
7Adrenal Cortex Hormones (Corticosteroids)IBA
06/2015 - 05/2000
7omalizumab (Xolair)FDA Link
05/2011 - 07/2004
7bosentan (Tracleer)FDA Link
07/2010 - 01/2003
6AntibodiesIBA
02/2010 - 02/2000
5MonocrotalineIBA
01/2015 - 08/2003
5Endothelin Receptors (Endothelin Receptor)IBA
02/2010 - 01/2003
3FenfluramineIBA
03/2010 - 09/2002
3Epoprostenol (Prostacyclin)FDA LinkGeneric
12/2009 - 01/2002
3Dexfenfluramine (Redux)IBA
03/2009 - 10/2002
3Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2004 - 01/2002
2corrigendumIBA
10/2015 - 10/2015
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2013 - 05/2004
2Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
08/2012 - 04/2011
2masitinibIBA
01/2012 - 08/2009
2Type II Bone Morphogenetic Protein Receptors (Bone Morphogenetic Protein Receptor Type II)IBA
04/2011 - 03/2010
2AntigensIBA
02/2010 - 09/2005
2Carbon MonoxideIBA
02/2010 - 04/2002
2anti-IgEIBA
01/2009 - 12/2005
2Budesonide (Pulmicort)FDA LinkGeneric
12/2008 - 07/2004
2OxygenIBA
01/2006 - 05/2004
2Immunoglobulin G (IgG)IBA
12/2005 - 09/2005
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
04/2003 - 02/2000
2Serotonin (5 Hydroxytryptamine)IBA
10/2002 - 07/2002
2Messenger RNA (mRNA)IBA
05/2001 - 04/2001
1Antisynthetase syndromeIBA
06/2015
1pifithrinIBA
01/2015
1AllergensIBA
05/2014
1Transforming Growth Factors (Transforming Growth Factor)IBA
08/2012
1Vinblastine (Vinblastine Sulfate)FDA Link
01/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2012
1gemcitabineFDA Link
01/2012
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2012
1JM 3100FDA Link
06/2011
1Dexamethasone (Maxidex)FDA LinkGeneric
04/2011
1Interleukin-6 (Interleukin 6)IBA
04/2011
1Anticardiolipin AntibodiesIBA
11/2010
1imatinib (Gleevec)FDA Link
11/2010
1Phosphopyruvate Hydratase (Enolase)IBA
02/2010
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
08/2009
1PDGF receptor tyrosine kinaseIBA
08/2009
1Iloprost (Ventavis)FDA Link
03/2009
1NorfenfluramineIBA
03/2009
1TitaniumIBA
03/2009
1benfluorex (S 780)IBA
03/2009

Therapy/Procedure

4Endarterectomy (Thromboendarterectomy)
02/2011 - 04/2004
4Lung Transplantation
12/2009 - 04/2004
2Highly Active Antiretroviral Therapy (HAART)
04/2012 - 01/2009
2Ligation
09/2009 - 05/2004