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Tom W J Huizinga Selected Research

Rheumatoid Arthritis

10/2015	Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent.
8/2015	Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study.
6/2015	Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate: Results of a Phase III Study.
5/2015	Comparative Efficacy of Novel DMARDs as Monotherapy and in Combination with Methotrexate in Rheumatoid Arthritis Patients with Inadequate Response to Conventional DMARDs: A Network Meta-Analysis.
4/2015	Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.
1/2015	Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.
1/2015	Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis.
1/2015	Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period.
1/2015	Retraction Note: Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium.
1/2015	The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.

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Tom W J Huizinga Research Topics

Disease

108	Rheumatoid Arthritis 10/2015 - 03/2003
38	Arthritis (Polyarthritis) 08/2015 - 02/2004
16	Inflammation 06/2015 - 06/2004
12	Osteoarthritis 01/2015 - 08/2003
7	Autoimmune Diseases (Autoimmune Disease) 09/2015 - 12/2004
6	Arthralgia (Joint Pain) 01/2015 - 04/2013
6	Experimental Arthritis 01/2015 - 10/2004
5	Pain (Aches) 07/2013 - 10/2008
4	Synovitis 05/2015 - 07/2010
4	Necrosis 12/2013 - 02/2007
4	Fibrosis (Cirrhosis) 06/2005 - 10/2003
3	Infection 01/2013 - 11/2005
3	Wounds and Injuries (Trauma) 01/2013 - 03/2003
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2006 - 04/2002
2	Chronic Disease (Chronic Diseases) 03/2014 - 09/2004
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2014 - 06/2004
2	Rubella (German Measles) 01/2012 - 01/2007
2	Leprosy (Hansen's Disease) 06/2004 - 12/2002
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 05/2002 - 04/2002
2	Multiple Sclerosis 05/2002 - 04/2002
1	Tenosynovitis 05/2015
1	Reactive Arthritis (Reiter Disease) 01/2015
1	Muscle Weakness 01/2015
1	Psoriatic Arthritis 01/2015
1	Body Weight (Weight, Body) 01/2015
1	Fatigue 01/2015
1	Edema 01/2015
1	Lupus Nephritis 11/2014
1	Neutropenia 09/2014
1	Anterior Uveitis 03/2014
1	Bone Resorption 01/2014
1	Obesity 08/2013
1	Transverse Myelitis (Necrotizing Myelitis) 06/2013

Drug/Important Bio-Agent (IBA)

42	AntibodiesIBA 10/2015 - 02/2004
18	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014 - 01/2002
17	Methotrexate (Mexate)FDA LinkGeneric 06/2015 - 04/2006
14	AntigensIBA 09/2015 - 10/2004
14	AutoantibodiesIBA 05/2015 - 02/2004
11	Antirheumatic Agents (DMARD)IBA 05/2015 - 10/2006
9	cyclic citrullinated peptideIBA 04/2013 - 01/2005
9	Interleukin-10 (Interleukin 10)IBA 08/2005 - 04/2002
8	Aminocaproic Acids (EAC)FDA LinkGeneric 01/2015 - 08/2005
8	Proteins (Proteins, Gene)IBA 01/2014 - 01/2005
7	Immunoglobulin G (IgG)IBA 01/2015 - 01/2006
6	Rheumatoid FactorIBA 05/2015 - 01/2007
6	acetyl 4-aminosalicylic acidIBA 01/2012 - 01/2007
5	CollagenIBA 01/2015 - 07/2004
5	rituximab (Mabthera)FDA Link 11/2014 - 12/2007
5	4-hexyloxyaniline (HOA)IBA 05/2014 - 07/2010
4	PeptidesIBA 01/2015 - 07/2004
4	Immunoglobulin M (IgM)IBA 04/2014 - 01/2006
4	Prednisone (Sone)FDA LinkGeneric 06/2013 - 05/2009
4	VimentinIBA 07/2011 - 08/2009
4	HLA-DRB1 antigen (HLA DRB1)IBA 05/2010 - 10/2005
3	abatacept (BELATACEPT)FDA Link 01/2015 - 09/2010
3	C-Reactive ProteinIBA 01/2015 - 09/2013
3	InterleukinsIBA 01/2015 - 12/2002
3	Fibrinogen (Factor I)FDA Link 10/2014 - 01/2011
3	AdiponectinIBA 05/2014 - 07/2011
3	EpitopesIBA 02/2012 - 08/2010
3	TNF Receptor-Associated Factor 1IBA 02/2011 - 09/2007
3	Messenger RNA (mRNA)IBA 06/2010 - 10/2003
3	Interleukin-1 (Interleukin 1)IBA 05/2005 - 05/2002
3	Interleukin-1beta (Interleukin 1 beta)IBA 05/2005 - 05/2002
2	GadoliniumIBA 05/2015 - 10/2014
2	CitrullineIBA 01/2015 - 02/2012
2	Collagen Type II (Type II Collagen)IBA 01/2015 - 01/2014
2	Carbon MonoxideIBA 01/2015 - 10/2005
2	LipidsIBA 09/2014 - 08/2013
2	pyridinolineIBA 08/2013 - 07/2004
2	TNFR-Fc fusion protein (etanercept)FDA Link 03/2013 - 02/2007
2	amsonic acid (DAS)IBA 06/2012 - 06/2009
2	ResistinIBA 09/2011 - 07/2011
2	LeptinIBA 09/2011 - 07/2011
2	Interleukin-6 (Interleukin 6)IBA 09/2011 - 09/2004
2	AdipokinesIBA 09/2011 - 07/2011
2	Phosphopyruvate Hydratase (Enolase)IBA 07/2011 - 01/2011
2	CytokinesIBA 01/2011 - 09/2004
2	Insulin (Novolin)FDA Link 06/2010 - 02/2005
2	Prednisolone (Predate)FDA LinkGeneric 06/2010 - 02/2007
2	HLA-DR Antigens (HLA-DR)IBA 12/2007 - 07/2004
2	adalimumab (Humira)FDA Link 02/2007 - 02/2006
2	2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine (Lysyl Hydroxylase)IBA 06/2005 - 10/2003
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 09/2004 - 05/2002
1	Galactose (Galactopyranose)FDA LinkGeneric 01/2015
1	OxygenIBA 01/2015
1	belimumabIBA 11/2014
1	3-benzoyl dopamine (MBDA)IBA 11/2014
1	TransaminasesIBA 09/2014
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 09/2014
1	HLA-B60IBA 03/2014
1	Freund's AdjuvantIBA 01/2014
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 01/2014
1	OsteoprotegerinIBA 01/2014
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 09/2013
1	Antiphospholipid AntibodiesIBA 06/2013
1	HLA Antigens (Human Leukocyte Antigens)IBA 06/2013

Therapy/Procedure

3	Injections 10/2010 - 09/2006
2	Remission Induction 08/2015 - 09/2012
1	Activities of Daily Living (ADL) 07/2013