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Rikard Holmdahl Selected Research

Rheumatoid Arthritis

1/2016	Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation.
8/2015	B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.
6/2015	Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes.
2/2015	Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.
1/2015	Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage.
1/2015	Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis.
8/2014	Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner.
6/2014	Identification of new citrulline-specific autoantibodies, which bind to human arthritic cartilage, by mass spectrometric analysis of citrullinated type II collagen.
1/2014	Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.
1/2014	Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.

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Rikard Holmdahl Research Topics

Disease

118	Arthritis (Polyarthritis) 01/2016 - 01/2002
79	Rheumatoid Arthritis 01/2016 - 02/2002
59	Experimental Arthritis 08/2015 - 05/2002
32	Inflammation 08/2015 - 01/2002
17	Autoimmune Diseases (Autoimmune Disease) 08/2015 - 01/2002
6	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2016 - 10/2006
5	Chronic Granulomatous Disease 12/2014 - 11/2012
5	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 07/2010 - 07/2002
4	Multiple Sclerosis 01/2016 - 01/2003
4	Neoplasms (Cancer) 01/2015 - 10/2010
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2014 - 09/2002
4	Hypersensitivity (Allergy) 12/2012 - 08/2004
4	Relapsing Polychondritis 03/2004 - 01/2002
3	Infection 12/2014 - 04/2013
3	Necrosis 08/2010 - 08/2005
2	Gout 01/2016 - 05/2014
2	Colitis 08/2014 - 01/2014
2	Pathologic Processes 11/2011 - 01/2010
2	Osteoarthritis 01/2011 - 09/2002
2	Skin Diseases 04/2008 - 10/2006
2	Demyelinating Diseases (Demyelinating Disease) 03/2003 - 07/2002
1	Fatty Liver 02/2015
1	Alcoholic Fatty Liver 02/2015
1	Sarcoma (Soft Tissue Sarcoma) 01/2015
1	Emphysema 01/2015

Drug/Important Bio-Agent (IBA)

71	Collagen Type II (Type II Collagen)IBA 08/2015 - 01/2002
43	AntibodiesIBA 08/2015 - 09/2002
32	CollagenIBA 08/2014 - 01/2002
25	pristane (pristan)IBA 03/2015 - 01/2002
23	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2015 - 09/2005
20	NADPH Oxidase (NAD(P)H oxidase)IBA 01/2016 - 01/2003
18	Immunoglobulin G (IgG)IBA 12/2014 - 09/2002
15	AntigensIBA 08/2015 - 08/2005
13	Proteins (Proteins, Gene)IBA 01/2015 - 01/2002
12	AutoantibodiesIBA 08/2015 - 09/2002
11	PeptidesIBA 06/2015 - 05/2007
11	Monoclonal AntibodiesIBA 06/2011 - 09/2002
9	EpitopesIBA 01/2014 - 09/2002
7	neutrophil cytosolic factor 1IBA 01/2012 - 01/2003
6	acetyl 4-aminosalicylic acidIBA 02/2015 - 01/2010
6	cartilage matrix proteinIBA 09/2013 - 01/2002
6	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 07/2013 - 06/2002
5	CytokinesIBA 05/2014 - 01/2004
5	Complement System Proteins (Complement)IBA 10/2013 - 03/2004
4	Antigen-Antibody Complex (Immune Complex)IBA 06/2013 - 07/2004
4	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 11/2012 - 02/2007
4	NADP (NADPH)IBA 07/2012 - 09/2005
4	AutoantigensIBA 12/2011 - 01/2002
4	GlycopeptidesIBA 01/2011 - 12/2002
3	CitrullineIBA 01/2015 - 02/2009
3	OxygenIBA 08/2014 - 08/2007
3	Immunoglobulin M (IgM)IBA 07/2013 - 12/2003
3	Mineral Oil (Liquid Paraffin)FDA LinkGeneric 12/2012 - 12/2007
3	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2011 - 01/2010
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2007 - 12/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2006 - 02/2002
3	oligodendrocyte-myelin glycoproteinIBA 08/2004 - 07/2002
2	HLA-DR Antigens (HLA-DR)IBA 03/2015 - 08/2012
2	HLA-DQ Antigens (HLA-DQ)IBA 03/2015 - 08/2012
2	Toll-Like Receptor 2IBA 02/2015 - 07/2012
2	L 012IBA 08/2014 - 09/2009
2	NitrogenIBA 08/2014 - 09/2009
2	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 10/2013 - 01/2005
2	Carbon MonoxideIBA 08/2013 - 01/2012
2	poly(N-isopropylacrylamide)IBA 08/2013 - 11/2011
2	PolymersIBA 08/2013 - 11/2011
2	Peptide Hydrolases (Proteases)IBA 07/2013 - 01/2011
2	AsparagineIBA 06/2013 - 10/2007
2	Fibrinogen (Factor I)FDA Link 05/2013 - 01/2002
2	Superoxides (Superoxide)IBA 04/2013 - 01/2012
2	Proteoglycans (Proteoglycan)IBA 03/2013 - 06/2011
2	Collagen Type XIIBA 08/2012 - 05/2002
2	OvalbuminIBA 08/2011 - 09/2008
2	Toll-Like Receptor 3IBA 01/2011 - 01/2010
2	OxidoreductasesIBA 10/2010 - 09/2005
2	Fc Receptors (Fc Receptor)IBA 05/2010 - 08/2003
2	Estrogens (Estrogen)FDA Link 01/2010 - 11/2003
2	Staphylococcal Protein A (A, Protein)IBA 09/2009 - 01/2005
2	Rheumatoid FactorIBA 09/2008 - 12/2003
2	Lysine (L-Lysine)FDA Link 08/2008 - 10/2004
2	Freund's AdjuvantIBA 07/2008 - 05/2007
2	IntegrinsIBA 04/2008 - 10/2006
2	cryogelIBA 07/2007 - 01/2005
2	Interferon-betaIBA 01/2007 - 12/2005
2	PhytolIBA 01/2007 - 09/2006
2	Glycoproteins (Glycoprotein)IBA 01/2007 - 01/2002
2	Interleukin-4 (Interleukin 4)IBA 06/2006 - 10/2002
2	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 03/2006 - 03/2005
2	glycosylated collagenIBA 02/2006 - 07/2002
2	Fibrinolysin FDA Link 08/2005 - 03/2005
2	PlasminogenIBA 08/2005 - 03/2005
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 08/2015
1	MicroRNAs (MicroRNA)IBA 02/2015
1	MethylcholanthreneIBA 01/2015
1	Pancreatic Elastase (Elastase)IBA 01/2015

Therapy/Procedure

3	Injections 09/2014 - 03/2005
3	Transplantation (Transplant Recipients) 10/2010 - 06/2002
2	Subcutaneous Injections 01/2011 - 01/2007
2	Intraperitoneal Injections 02/2007 - 09/2005
2	Intravenous Injections 09/2005 - 07/2004