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Christine Hoffer Selected Research

Alfentanil (Alfenta)

10/2005Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity.
11/2004Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis.
3/2003Disposition and miotic effects of oral alfentanil: a potential noninvasive probe for first-pass cytochrome P4503A activity.

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Christine Hoffer Research Topics

Disease

10Miosis
05/2009 - 03/2003
3Pain (Aches)
09/2004 - 09/2004
2Neoplasms (Cancer)
09/2004 - 09/2004
1Respiratory Insufficiency (Respiratory Failure)
09/2004

Drug/Important Bio-Agent (IBA)

4Cytochrome P-450 CYP3AIBA
10/2005 - 03/2003
3Methadone (Dolophine)FDA LinkGeneric
05/2009 - 05/2004
3Alfentanil (Alfenta)FDA LinkGeneric
10/2005 - 03/2003
3Fentanyl (Sublimaze)FDA LinkGeneric
09/2004 - 03/2004
3Quinidine (Chinidin)FDA LinkGeneric
05/2004 - 12/2003
1Nelfinavir (Viracept)FDA Link
05/2009
1Oxycodone (Oxycontin)FDA LinkGeneric
05/2006
1Midazolam (Versed)FDA LinkGeneric
10/2005
1Methadyl Acetate (LAAM)FDA Link
01/2005
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
11/2004
1P-GlycoproteinIBA
05/2004
1Morphine (MS Contin)FDA LinkGeneric
12/2003

Therapy/Procedure

2Analgesia
09/2004 - 09/2004