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Takuya Hirata Selected Research

ramosetron (Nasea)

5/2014Inhibitory effect of the selective serotonin 5-HT₃ receptor antagonist ramosetron on duodenal acidification-induced gastric hypersensitivity in rats.
5/2009[Pharmacological and clinical profile of ramosetron hydrochloride (Irribow), a novel therapeutic agent for irritable bowel syndrome with diarrhea].
2/2008Inhibitory effects of ramosetron, a potent and selective 5-HT3-receptor antagonist, on conditioned fear stress-induced abnormal defecation and normal defecation in rats: comparative studies with antidiarrheal and spasmolytic agents.
11/2007Effect of ramosetron on conditioned emotional stress-induced colonic dysfunction as a model of irritable bowel syndrome in rats.
7/2007Evaluation of the pharmacological profile of ramosetron, a novel therapeutic agent for irritable bowel syndrome.

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Takuya Hirata Research Topics

Disease

4Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
05/2009 - 07/2007
4Diarrhea
05/2009 - 07/2007
1Pulmonary Artery Stenosis
08/2021
1Atrial Heart Septal Defects (Atrial Septal Defect)
08/2021
1Embolism (Embolus)
08/2021
1Pulmonary Hypertension
07/2019
1Transposition of Great Vessels (Great Vessels Transposition)
07/2019
1Cardiomyopathies (Cardiomyopathy)
11/2018
1Glycogen Storage Disease Type II (Pompe's Disease)
11/2018
1Hypersensitivity (Allergy)
05/2014
1Emphysema
01/2014
1Melanoma (Melanoma, Malignant)
08/2013
1Hepatocellular Carcinoma (Hepatoma)
10/2005
1Neoplasms (Cancer)
10/2005
1Bacterial Meningitis
04/2005

Drug/Important Bio-Agent (IBA)

5ramosetron (Nasea)IBA
05/2014 - 07/2007
3Serotonin (5 Hydroxytryptamine)IBA
05/2014 - 11/2007
2Loperamide (Imodium)FDA LinkGeneric
02/2008 - 07/2007
15-HT3 Serotonin Receptors (5 HT3 Receptor)IBA
05/2014
1Colloids (Colloid)IBA
08/2013
1Blood Proteins (Serum Proteins)IBA
08/2013
1poly(lactide) (polylactic acid)IBA
08/2013
1hydroxyapatite-polylactideIBA
08/2013
1Durapatite (Hydroxylapatite)IBA
08/2013
1AntidiarrhealsIBA
02/2008
1TrimebutineIBA
02/2008
1Parasympatholytics (Antispasmodics)IBA
02/2008
1Pharmaceutical PreparationsIBA
11/2007
1cilansetronIBA
07/2007
1alosetron (Lotronex)FDA Link
07/2007
1Contrast MediaIBA
10/2005
1perflutren (octafluoropropane)FDA Link
10/2005
1Thrombopoietin (c-mpl Ligand)IBA
04/2005

Therapy/Procedure

1Liver Transplantation
08/2021
1Catheters
08/2021
1Lung Transplantation
07/2019
1Enzyme Replacement Therapy
11/2018
1Mechanical Ventilators (Ventilator)
01/2014
1Microspheres (Microsphere)
08/2013