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Alexander Hergovich Selected Research

Long-Acting Thyroid Stimulator (LATS)

1/2015The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility.
6/2011Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression.
9/2010Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.
11/2009The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation.
7/2009Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling.

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Alexander Hergovich Research Topics

Disease

14Neoplasms (Cancer)
02/2015 - 09/2003
3Warts (Wart)
01/2013 - 07/2009
1Colorectal Neoplasms (Colorectal Cancer)
02/2015
1Glioma (Gliomas)
01/2013
1Chondrosarcoma
01/2013
1Cholangiocarcinoma
01/2013
1Neoplasm Metastasis (Metastasis)
01/2012
1Breast Neoplasms (Breast Cancer)
01/2012
1T-Cell Lymphoma (Lymphoma, T Cell)
01/2010
1Renal Cell Carcinoma (Grawitz Tumor)
02/2009
1Shock
08/2008

Drug/Important Bio-Agent (IBA)

12Phosphotransferases (Kinase)IBA
02/2015 - 09/2005
5Long-Acting Thyroid Stimulator (LATS)IBA
01/2015 - 07/2009
2methylallyl trisulfide (MATS)IBA
01/2013 - 02/2012
2Carbon MonoxideIBA
01/2013 - 01/2012
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2013
1A-Form DNA (A-DNA)IBA
01/2013
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
01/2013
1ChromatinIBA
01/2013
1Transcription Factors (Transcription Factor)IBA
01/2013
1OSM-LIF ReceptorsIBA
01/2012
1Proteins (Proteins, Gene)IBA
01/2010
1Protein Kinases (Protein Kinase)IBA
07/2009
1Cadherins (E-Cadherin)IBA
02/2009
1occludinIBA
02/2009
1claudin 1 (CLDN1)IBA
02/2009
1Okadaic AcidIBA
08/2008
1calyculin AIBA
08/2008
1chelerythrineIBA
08/2008
1Glycogen Synthase Kinase 3IBA
08/2006
1Protein Isoforms (Isoforms)IBA
09/2003