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David W Hein Selected Research

Carcinogens

1/2013Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium.
2/2011Lack of association of the N-acetyltransferase NAT1*10 allele with prostate cancer incidence, grade, or stage among smokers in Finland.
7/2009Effects of dietary factors and the NAT2 acetylator status on gastric cancer in Koreans.
1/20094-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
7/2008Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.
1/2008Chemoprevention of arylamine-induced colorectal aberrant crypts.
1/2008Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1.
9/2006Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma.
1/2006Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer.
11/2004The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation.
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David W Hein Research Topics

Disease

21Neoplasms (Cancer)
05/2012 - 01/2002
7Breast Neoplasms (Breast Cancer)
11/2009 - 07/2003
5Urinary Bladder Neoplasms (Bladder Cancer)
12/2011 - 03/2003
4Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2013 - 08/2006
4Inflammation
06/2009 - 12/2003
4Colorectal Neoplasms (Colorectal Cancer)
02/2008 - 09/2006
3Congenital Abnormalities (Deformity)
02/2011 - 09/2007
3Prostatic Neoplasms (Prostate Cancer)
01/2009 - 01/2002
3Pancreatic Neoplasms (Pancreatic Cancer)
06/2008 - 01/2006
3Adenocarcinoma
06/2008 - 07/2004
2Hepatocellular Carcinoma (Hepatoma)
06/2015 - 07/2006
2Stomach Neoplasms (Stomach Cancer)
07/2009 - 03/2005
2Cardiomyopathies (Cardiomyopathy)
06/2009 - 08/2008
2Diabetic Cardiomyopathies
06/2009 - 08/2008
2Adenoma (Adenomas)
02/2008 - 03/2002
2Hepatitis
01/2006 - 12/2003
2Necrosis
01/2006 - 12/2003
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2013
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
01/2012
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2010
1Lung Neoplasms (Lung Cancer)
10/2010
1HIV Infections (HIV Infection)
05/2010
1Fibrosis (Cirrhosis)
06/2009
1Lymphoma (Lymphomas)
12/2008
1Atopic Dermatitis (Atopic Eczema)
12/2008
1Colonic Neoplasms (Colon Cancer)
02/2008
1Polyps
02/2008
1Leukemia
10/2007
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
10/2007
1Asthma (Bronchial Asthma)
10/2007
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
07/2007
1Contagious Ecthyma (Orf)
05/2007
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2007
1Drug Toxicity (Drug Safety)
01/2005
1Ischemia
09/2004
1Genetic Predisposition to Disease (Genetic Predisposition)
06/2004
1Body Weight (Weight, Body)
12/2003

Drug/Important Bio-Agent (IBA)

17N-acetyltransferase 1IBA
01/2013 - 01/2002
16CarcinogensIBA
01/2013 - 01/2002
10EnzymesIBA
01/2013 - 01/2006
6SmokeIBA
11/2009 - 07/2003
5N-acetyltalosaminuronic acid (NAT)IBA
05/2012 - 08/2005
5DNA (Deoxyribonucleic Acid)IBA
05/2012 - 03/2005
5AminesIBA
11/2009 - 09/2002
5Cytochrome P-450 CYP1A2 (CYP1A2)IBA
06/2008 - 03/2002
4CytochromesIBA
06/2008 - 03/2003
3Arylamine N-AcetyltransferaseIBA
05/2012 - 07/2008
3Glutathione Transferase (Glutathione S-Transferase)IBA
12/2011 - 07/2003
3Hair DyesIBA
12/2011 - 03/2003
3Superoxide DismutaseIBA
10/2010 - 03/2005
3AcetyltransferasesIBA
01/2010 - 03/2003
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2009 - 09/2004
2MetallothioneinIBA
06/2009 - 08/2008
2MutagensIBA
02/2008 - 08/2006
2Messenger RNA (mRNA)IBA
05/2007 - 07/2006
2Alanine Transaminase (SGPT)IBA
01/2006 - 09/2004
1Estrogens (Estrogen)FDA Link
06/2015
1GTP-Binding Proteins (G-Protein)IBA
06/2015
1Dehydroepiandrosterone (DHEA)IBA
06/2015
1Genetic Markers (Genetic Marker)IBA
01/2012
1Coloring Agents (Dyes)IBA
12/2011
1Adenocarcinoma of lungIBA
10/2010
1Retinoblastoma ProteinIBA
01/2010
1Cyclin D1IBA
01/2010
12- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA
11/2009
1benzocycloheptapyridineIBA
11/2009
1ORALIT (ORS)IBA
11/2009
1Plasminogen Activator Inhibitor 1IBA
06/2009
1Glycogen Synthase (Synthase I)IBA
06/2009
1Glycogen Synthase KinasesIBA
06/2009
1glycogen synthase kinase 3 betaIBA
06/2009
1Glucose (Dextrose)FDA LinkGeneric
06/2009
1HexokinaseIBA
06/2009
1PPAR alphaIBA
06/2009
1Histamine N-MethyltransferaseIBA
12/2008
1Histamine (Histamine Dihydrochloride)FDA Link
12/2008
1hydrazine (hydrazine dihydrochloride)IBA
07/2008
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
02/2008
1celecoxib (Celebrex)FDA Link
02/2008
12',3-dimethyl-4-aminobiphenylIBA
02/2008
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/2008
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2008
1XenobioticsIBA
09/2007
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
05/2007
1NucleotidesIBA
05/2007
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
09/2004
1Losartan (Cozaar)FDA LinkGeneric
09/2004
14-hydroxy-2-nonenal (4-hydroxynonenal)IBA
09/2004
1Captopril (Capoten)FDA LinkGeneric
09/2004
1Complementary DNA (cDNA)IBA
07/2004
1Environmental CarcinogensIBA
06/2004
1glutathione S-transferase M1IBA
04/2004
1Peroxynitrous Acid (Peroxynitrite)IBA
12/2003
1Ethanol (Ethyl Alcohol)IBA
12/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2003
1Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2003

Therapy/Procedure

2Chemoprevention
02/2008 - 04/2004
1Transplantation (Transplant Recipients)
10/2007
1Drug Therapy (Chemotherapy)
01/2006
1Radiotherapy
01/2006