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Catherine P M Hayward Selected Research

Quebec platelet disorder

12/2020Thrombin generation abnormalities in Quebec platelet disorder.
12/2020Improved platelet counts during prolonged tranexamic therapy for Quebec platelet disorder implicate the underlying fibrinolytic defect as the cause of lower platelet counts.
1/2017The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes.
9/2011Quebec platelet disorder: update on pathogenesis, diagnosis, and treatment.
2/2010Persons with Quebec platelet disorder have a tandem duplication of PLAU, the urokinase plasminogen activator gene.
2/2009Quebec platelet disorder is linked to the urokinase plasminogen activator gene (PLAU) and increases expression of the linked allele in megakaryocytes.
2/2009Increased expression of urokinase plasminogen activator in Quebec platelet disorder is linked to megakaryocyte differentiation.
7/2004Bleeding risks associated with inheritance of the Quebec platelet disorder.
8/2003Intracellular activation of the fibrinolytic cascade in the Quebec Platelet Disorder.

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Catherine P M Hayward Research Topics

Disease

16Hemorrhage
07/2022 - 08/2003
9Quebec platelet disorder
12/2020 - 08/2003
3Thrombocytopenia (Thrombopenia)
07/2022 - 10/2004
3Thrombosis (Thrombus)
07/2022 - 05/2010
1Venous Thromboembolism
07/2022
1Hemophilia A (Haemophilia)
07/2022
1Thromboinflammation
07/2022
1Thrombophilia
01/2021
1Wounds and Injuries (Trauma)
01/2021
1Fibrinolytic Defect
12/2020
1Factor XIII Deficiency
03/2014
1Epistaxis (Nosebleed)
03/2009
1Menorrhagia
03/2009
1Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders)
12/2008
1Bernard-Soulier Syndrome (Giant Platelet Syndrome)
07/2008
1Type 2 von Willebrand Disease
07/2008
1Thrombotic Thrombocytopenic Purpura
12/2004
1Glycogen Storage Disease Type VI (Glycogenosis Type VI)
12/2004
1Chronic Kidney Failure (Chronic Renal Failure)
12/2004
1Hemolytic-Uremic Syndrome
12/2004
1Purpura
07/2004
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
07/2004

Drug/Important Bio-Agent (IBA)

9Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
12/2020 - 08/2003
7Plasminogen Activators (Plasminogen Activator)IBA
12/2020 - 03/2008
3Proteins (Proteins, Gene)FDA Link
12/2020 - 08/2003
3Hemostatics (Antihemorrhagics)IBA
03/2009 - 07/2004
2ThrombinFDA Link
12/2021 - 12/2020
2multimerinIBA
01/2021 - 05/2010
2FibrinolysinFDA Link
12/2020 - 02/2009
2Fibrinogen (Factor I)FDA Link
10/2012 - 12/2008
2von Willebrand FactorIBA
05/2012 - 12/2004
2Heparin (Liquaemin)FDA LinkGeneric
12/2007 - 10/2004
1VaccinesIBA
07/2022
1A-factor (Streptomyces)IBA
01/2021
1Fibrillar CollagensIBA
01/2021
1ferric chlorideIBA
01/2021
1lipoprotein-associated coagulation inhibitor (TFPI)IBA
12/2020
1Factor V (Coagulation Factor V)IBA
12/2020
1ORALIT (ORS)IBA
07/2020
1CollagenIBA
07/2020
1Factor XIII (Coagulation Factor XIII)IBA
03/2014
1Blood Coagulation Factors (Coagulation Factor)IBA
05/2012
1alpha-SynucleinIBA
05/2010
1RistocetinIBA
07/2008
1EnzymesIBA
03/2008
1thiamine triphosphorate (TTP)IBA
12/2004
1ADAMTS13 ProteinIBA
12/2004
1Abciximab (ReoPro)FDA Link
10/2004
1AntibodiesIBA
07/2004
1Inosine Triphosphate (ITP)IBA
07/2004

Therapy/Procedure

4Therapeutics
12/2020 - 12/2004