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Nobutaka Hattori Selected Research

Parkinson Disease (Parkinson's Disease)

11/2015	Asian perspectives on the recognition and management of levodopa 'wearing-off' in Parkinson's disease.
11/2015	A Randomized Controlled Trial of Subcutaneous Apomorphine for Parkinson Disease: A Repeat Dose and Pharmacokinetic Study.
10/2015	Large-scale assessment of polyglutamine repeat expansions in Parkinson disease.
9/2015	The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.
9/2015	The prevalence and risk factors of cerebral microbleeds in patients with Parkinson's disease.
8/2015	Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease.
7/2015	Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
7/2015	Utility of the Japanese version of the 9-item Wearing-off Questionnaire.
4/2015	Variants associated with Gaucher disease in multiple system atrophy.
3/2015	CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study.

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Nobutaka Hattori Research Topics

Disease

99	Parkinson Disease (Parkinson's Disease) 11/2015 - 05/2002
29	Parkinsonian Disorders (Parkinsonism) 11/2014 - 08/2002
15	Stroke (Strokes) 12/2015 - 04/2009
15	Dementia (Dementias) 07/2015 - 05/2002
11	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2015 - 12/2003
8	Dyskinesias (Dyskinesia) 01/2015 - 04/2007
6	Restless Legs Syndrome (Restless Legs) 07/2015 - 03/2012
6	Alzheimer Disease (Alzheimer's Disease) 07/2015 - 04/2004
5	Huntington Disease (Huntington's Disease) 02/2015 - 04/2004
5	Tremor (Tremors) 12/2014 - 08/2007
4	Hypertension (High Blood Pressure) 12/2015 - 03/2014
4	Tauopathies 11/2015 - 12/2008
4	Brain Ischemia (Cerebral Ischemia) 06/2014 - 11/2009
4	Atherosclerosis 02/2014 - 04/2004
4	Cerebral Infarction 11/2013 - 11/2009
4	Neoplasms (Cancer) 01/2013 - 02/2011
4	Ischemia 08/2011 - 07/2008
3	Infarction 02/2015 - 04/2009
3	Frontotemporal Lobar Degeneration (Semantic Dementia) 01/2015 - 12/2008
3	Endometriosis (Adenomyosis) 08/2014 - 10/2012
3	Bipolar Disorder (Mania) 06/2014 - 08/2009
3	Neuromyelitis Optica (Devic's Disease) 01/2013 - 09/2009
3	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2013 - 08/2002
2	Prediabetic State (Prediabetes) 12/2015 - 09/2013
2	Type 2 Diabetes Mellitus (MODY) 12/2015 - 08/2011
2	Intracranial Embolism 04/2015 - 02/2015
2	Gaucher Disease (Gaucher's Disease) 04/2015 - 01/2007
2	Disease Progression 01/2015 - 01/2003
2	Fever (Fevers) 01/2015 - 12/2010
2	Ataxia (Dyssynergia) 12/2014 - 05/2013
2	Atrophy 04/2014 - 03/2010
2	Polyneuropathies (Polyneuropathy) 02/2014 - 09/2013
2	Infection 01/2014 - 09/2009
2	Insulin Resistance 01/2014 - 04/2009
2	Human Influenza (Influenza) 01/2014 - 01/2008
2	Meningitis 09/2013 - 01/2013
2	Myocardial Infarction 04/2013 - 08/2011
2	Hemorrhage 04/2013 - 11/2012
2	Lymphoma (Lymphomas) 04/2013 - 01/2003
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2013 - 04/2006
2	Aneurysm (Aneurysms) 01/2013 - 01/2011
2	Nervous System Diseases (Neurological Disorders) 01/2013 - 01/2008
2	Reperfusion Injury 08/2011 - 11/2009
2	Neurologic Manifestations (Neurological Manifestations) 08/2011 - 11/2009
2	Renal Insufficiency (Renal Failure) 12/2010 - 12/2009
2	Hypercholesterolemia 08/2010 - 01/2009

Drug/Important Bio-Agent (IBA)

23	Levodopa (L Dopa)FDA LinkGeneric 11/2015 - 06/2003
19	Phosphotransferases (Kinase)IBA 09/2015 - 03/2006
17	alpha-SynucleinIBA 02/2009 - 05/2002
13	UbiquitinIBA 06/2014 - 03/2003
12	Leucine (L-Leucine)FDA Link 09/2015 - 09/2006
8	SynucleinsIBA 07/2015 - 11/2010
7	AntibodiesIBA 07/2015 - 05/2002
6	N 0437 FDA Link 07/2015 - 01/2013
5	Glucose (Dextrose)FDA LinkGeneric 12/2015 - 04/2009
5	polyglutamineIBA 10/2015 - 10/2005
5	Proteins (Proteins, Gene)IBA 02/2015 - 08/2004
5	PTEN-induced putative kinaseIBA 09/2014 - 08/2007
5	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 02/2006 - 08/2002
4	tau Proteins (tau Protein)IBA 11/2015 - 02/2011
4	Dopamine Agonists (Dopamine Agonist)IBA 06/2015 - 12/2003
4	DNA (Deoxyribonucleic Acid)IBA 03/2015 - 08/2002
4	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2014 - 04/2004
4	Dopamine (Intropin)FDA LinkGeneric 09/2010 - 11/2006
4	cytidylyl-(3'-5')-cytidine (CpC)IBA 12/2005 - 01/2003
3	fibrin fragment D (D-dimer)IBA 12/2015 - 10/2012
3	rosuvastatin (Crestor)FDA Link 04/2015 - 01/2009
3	Glucosylceramidase (Glucocerebrosidase)IBA 04/2015 - 01/2007
3	tebufenozide (Mimic)IBA 02/2015 - 01/2011
3	Lipoproteins (Lipoprotein)IBA 04/2013 - 01/2009
3	pramipexol (pramipexole)FDA LinkGeneric 01/2013 - 01/2011
3	Immunoglobulin G (IgG)IBA 01/2013 - 09/2009
3	Insulin (Novolin)FDA Link 11/2011 - 01/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2011 - 04/2007
3	3-Iodobenzylguanidine (Iobenguane)IBA 01/2011 - 10/2005
3	Pergolide (Permax)FDA Link 01/2010 - 12/2003
2	ApomorphineIBA 11/2015 - 08/2014
2	glucuronyl glucosamine glycan sulfate (Vessel)IBA 09/2015 - 09/2010
2	Uric Acid (Urate)IBA 03/2015 - 01/2014
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 02/2015 - 01/2015
2	LithiumIBA 06/2014 - 04/2012
2	Glutamic Acid (Glutamate)FDA Link 06/2014 - 07/2009
2	Staphylococcal Protein A (A, Protein)IBA 06/2014 - 11/2009
2	AdrenomedullinIBA 01/2014 - 11/2009
2	Yi-Gan SanIBA 01/2014 - 03/2010
2	Amantadine (Aman)FDA LinkGeneric 11/2013 - 01/2008
2	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 09/2013 - 11/2012
2	Peroxidase (Myeloperoxidase)IBA 09/2013 - 11/2012
2	LDL CholesterolIBA 04/2013 - 01/2009
2	Amyloid (Amyloid Fibrils)IBA 01/2013 - 01/2012
2	AutoantibodiesIBA 01/2013 - 04/2006
2	1- (((alpha- isobutanoyloxyethoxy)carbonyl)aminomethyl)- 1- cyclohexaneacetic acidIBA 01/2013 - 03/2012
2	Type 1 Angiotensin ReceptorIBA 07/2012 - 07/2008
2	Antipsychotic Agents (Antipsychotics)IBA 01/2012 - 08/2009
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 08/2011 - 08/2011

Therapy/Procedure

5	Deep Brain Stimulation 12/2014 - 03/2011
3	Activities of Daily Living (ADL) 09/2013 - 03/2009
2	Aftercare (After-Treatment) 01/2015 - 10/2012
2	Drug Therapy (Chemotherapy) 02/2014 - 05/2013
2	Renal Dialysis (Hemodialysis) 01/2013 - 12/2009