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Paul M Hassoun Selected Research

Idiopathic pulmonary hypertension

11/2015Ambrisentan and Tadalafil Up-front Combination Therapy in Scleroderma-associated Pulmonary Arterial Hypertension.
6/2015Right ventricular remodeling in idiopathic and scleroderma-associated pulmonary arterial hypertension: two distinct phenotypes.
3/2015Interleukin-6 and tumor necrosis factor-α are associated with quality of life-related symptoms in pulmonary arterial hypertension.
2/2015Perspectives on oral pulmonary hypertension therapies recently approved by the U.S. Food and Drug Administration.
12/2014Unique predictors of mortality in patients with pulmonary arterial hypertension associated with systemic sclerosis in the REVEAL registry.
10/2014Update in systemic sclerosis-associated pulmonary arterial hypertension.
7/2014Severity of systemic sclerosis-associated pulmonary arterial hypertension in African Americans.
7/2014Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Pulmonary arterial hypertension associated with connective tissue diseases.
3/2014Inflammation in pulmonary arterial hypertension: is it time to quell the fire?
10/2013Systemic sclerosis-associated pulmonary arterial hypertension.
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Paul M Hassoun Research Topics

Disease

20Systemic Scleroderma (Systemic Sclerosis)
03/2015 - 02/2009
17Pulmonary Hypertension (Ayerza Syndrome)
11/2015 - 09/2003
11Acute Lung Injury
05/2014 - 11/2004
10Anoxia (Hypoxia)
01/2015 - 01/2002
10Lung Injury
09/2012 - 06/2004
8Inflammation
03/2015 - 03/2007
8Connective Tissue Diseases (Connective Tissue Disease)
12/2014 - 06/2009
5Heart Failure
03/2014 - 05/2008
5Interstitial Lung Diseases (Interstitial Lung Disease)
01/2012 - 02/2009
5Critical Illness (Critically Ill)
11/2009 - 11/2007
5Ventilator-Induced Lung Injury
12/2008 - 08/2005
3Emphysema
07/2014 - 03/2011
3Vascular Diseases (Vascular Disease)
03/2014 - 11/2010
3Hyperoxia
11/2009 - 06/2009
2Ventricular Remodeling
06/2015 - 06/2012
2Schistosomiasis (Bilharziasis)
07/2014 - 09/2010
2Infection
07/2014 - 06/2002
2Hypertension (High Blood Pressure)
09/2013 - 05/2008
2Lung Diseases (Lung Disease)
03/2011 - 11/2004
2Mixed Connective Tissue Disease (MCTD)
12/2010 - 08/2009
2Rheumatoid Arthritis
12/2010 - 08/2009
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
12/2010 - 08/2009
2Adult Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
12/2007 - 11/2007
2Pulmonary Edema
09/2006 - 11/2004
1Channelopathies
01/2016
1Rare Diseases (Rare Disease)
11/2015
1Chronic Disease (Chronic Diseases)
03/2015
1Pain (Aches)
03/2015
1Cardiomyopathies (Cardiomyopathy)
03/2015
1Hypotension (Low Blood Pressure)
02/2015
1Headache (Headaches)
02/2015
1Chronic Obstructive Pulmonary Disease (COPD)
07/2014
1Portal Hypertension
07/2014
1Obstructive Lung Diseases (Obstructive Lung Disease)
07/2014
1Heart Diseases (Heart Disease)
07/2014
1Right Ventricular Dysfunction
09/2013
1Stroke (Strokes)
09/2013
1Ataxia Telangiectasia (Louis Bar Syndrome)
07/2013
1Subdural Hematoma (Subdural Hemorrhage)
03/2013
1AIDS-Related Complex (ARC)
12/2011
1Hypertrophy
12/2011
1Hemorrhage
06/2011
1Pericardial Effusion
12/2010
1Edema
02/2010
1Body Weight (Weight, Body)
11/2009
1Sarcoidosis (Schaumann Disease)
06/2009
1Pathologic Processes
12/2008

Drug/Important Bio-Agent (IBA)

36Idiopathic pulmonary hypertensionIBA
11/2015 - 06/2008
6Xanthine DehydrogenaseIBA
01/2015 - 04/2003
6p38 Mitogen-Activated Protein KinasesIBA
02/2010 - 11/2002
4Simvastatin (Zocor)FDA LinkGeneric
03/2015 - 09/2003
4SmokeIBA
07/2014 - 04/2003
3Protein Kinases (Protein Kinase)IBA
11/2015 - 01/2009
3Phosphotransferases (Kinase)IBA
01/2015 - 11/2002
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
09/2012 - 01/2002
3beta-cyclodextrin tetradecasulfate (CTDS)IBA
07/2012 - 08/2009
3EnzymesIBA
11/2009 - 12/2007
3Reactive Oxygen Species (Oxygen Radicals)IBA
09/2006 - 01/2002
2imatinib (Gleevec)FDA Link
11/2015 - 03/2013
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2015 - 01/2002
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
03/2015 - 06/2011
2glucuronyl glucosamine glycan sulfate (Vessel)IBA
03/2015 - 09/2003
2CollagenIBA
03/2015 - 11/2010
27-(N-(3-aminopropyl)amino)heptan-2-oneIBA
12/2014 - 12/2010
2CytokinesIBA
10/2011 - 01/2002
2OxygenIBA
11/2009 - 10/2009
2Transcription Factors (Transcription Factor)IBA
11/2009 - 12/2007
2Glutathione (Reduced Glutathione)IBA
10/2009 - 06/2009
2sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
11/2004 - 06/2004
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2016
1HSP27 Heat-Shock ProteinsIBA
01/2016
1HLA-DRB5 (HLA DRB5)IBA
01/2016
1Interleukin-6 (Interleukin 6)IBA
03/2015
1pleiotrophin (HARP)IBA
03/2015
1treprostinilFDA Link
02/2015
1riociguatIBA
02/2015
1N- (5- (4- bromophenyl)- 6- (2- (5- bromopyrimidin- 2- yloxy)ethoxy)pyrimidin- 4- yl)- N'- propylaminosulfonamideIBA
02/2015
1CyclinsIBA
01/2015
1tranilast (N 5')IBA
09/2013
1Histones (Histone)IBA
07/2013
1DNA (Deoxyribonucleic Acid)IBA
07/2013
1Biological Markers (Surrogate Marker)IBA
06/2012
1Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA
12/2011
1Carbon MonoxideIBA
12/2010
1Brain Natriuretic Peptide (Natrecor)FDA Link
12/2010
1Interleukin-13IBA
09/2010
11- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA
11/2009
1Proteins (Proteins, Gene)IBA
11/2009
1imidazoleIBA
11/2009
1ResistinIBA
11/2009
1NF-E2-Related Factor 2IBA
10/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2009
1tyrphostin AG 1478IBA
12/2008
1Epidermal Growth Factor Receptor (EGF Receptor)IBA
12/2008

Therapy/Procedure

7Artificial Respiration (Mechanical Ventilation)
01/2009 - 11/2004
3Mechanical Ventilators (Ventilator)
01/2009 - 11/2004
2Heart Transplantation (Grafting, Heart)
03/2014 - 11/2008
1Transplants (Transplant)
03/2014
1Transplantation (Transplant Recipients)
03/2014
1Oral Administration
11/2009