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Kenji Hashimoto Selected Research

Fluvoxamine (Luvox)

1/2015Activation of sigma-1 receptor chaperone in the treatment of neuropsychiatric diseases and its clinical implication.
12/2013Benefical effects of sigma-1 agonist fluvoxamine for tardive dyskinesia and tardive akathisia in patients with schizophrenia: report of three cases.
10/2012A randomized, double-blind, placebo-controlled trial of fluvoxamine in patients with schizophrenia: a preliminary study.
9/2012Sigma-1 receptor agonist fluvoxamine for delirium in older adults.
1/2012Beneficial effects of the sigma-1 agonist fluvoxamine for tardive dyskinesia in patients with postpsychotic depressive disorder of schizophrenia: report of 5 cases.
1/2012Sigma-1 receptor agonists as therapeutic drugs for cognitive impairment in neuropsychiatric diseases.
1/2011Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder.
10/2010Fluvoxamine improved cognitive impairments in a patient with schizophrenia.
4/2010Cognition and depression: the effects of fluvoxamine, a sigma-1 receptor agonist, reconsidered.
1/2010Sigma-1 receptor agonist fluvoxamine for postoperative delirium in older adults: report of three cases.
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Kenji Hashimoto Research Topics

Disease

96Schizophrenia (Dementia Praecox)
06/2015 - 02/2002
19Major Depressive Disorder (Major Depressive Disorders)
12/2015 - 07/2003
16Alzheimer Disease (Alzheimer's Disease)
01/2015 - 04/2002
13Post-Traumatic Stress Disorders (PTSD)
12/2015 - 04/2010
11Neoplasms (Cancer)
02/2012 - 01/2006
10Bipolar Disorder (Mania)
02/2015 - 05/2004
9Mood Disorders (Mood Disorder)
01/2015 - 10/2002
9Eating Disorders (Eating Disorder)
05/2012 - 08/2003
8Autistic Disorder (Autism)
01/2013 - 12/2006
6Breast Neoplasms (Breast Cancer)
04/2013 - 07/2010
5Delirium
01/2015 - 01/2010
5Neoplasm Metastasis (Metastasis)
11/2011 - 11/2006
4Movement Disorders (Movement Disorder)
12/2015 - 01/2012
4Panic Disorder (Panic Attack)
10/2007 - 06/2004
3Infection
11/2015 - 03/2006
3Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
08/2015 - 10/2007
3Inflammation
02/2015 - 04/2014
3Neurodegenerative Diseases (Neurodegenerative Disease)
07/2014 - 12/2008
3Psychomotor Agitation (Akathisia)
10/2011 - 01/2010
3Pneumonia (Pneumonitis)
10/2010 - 03/2002
3Anorexia Nervosa
01/2010 - 08/2003
3Cardiac Arrhythmias (Arrythmia)
01/2010 - 01/2010
2Brain Injuries (Brain Injury)
03/2015 - 01/2010
2Liver Cirrhosis (Hepatic Cirrhosis)
01/2015 - 01/2014
2Dementia (Dementias)
05/2014 - 04/2013
2Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
12/2013 - 04/2010
2Hyperkinesis
12/2013 - 01/2012
2Wounds and Injuries (Trauma)
01/2013 - 04/2009
2Pain (Aches)
09/2012 - 01/2011
2Rhabdomyosarcoma
09/2012 - 07/2012
2Leukopenia
01/2012 - 01/2009
2Carcinoma (Carcinomatosis)
12/2011 - 11/2006
2Stomach Neoplasms (Stomach Cancer)
07/2010 - 08/2009
2Hemorrhage
08/2009 - 01/2009

Drug/Important Bio-Agent (IBA)

34N-Methylaspartate (NMDA)IBA
03/2015 - 02/2002
30Brain-Derived Neurotrophic Factor (BDNF)IBA
02/2015 - 07/2003
21sigma-1 receptor (receptor 1, sigma)IBA
03/2015 - 03/2007
17Serine (L-Serine)FDA Link
06/2015 - 06/2003
17Fluvoxamine (Luvox)FDA LinkGeneric
01/2015 - 03/2007
14Glutamic Acid (Glutamate)FDA Link
12/2015 - 02/2002
14Antipsychotic Agents (Antipsychotics)IBA
06/2013 - 02/2002
13Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2015 - 02/2002
13Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2015 - 04/2002
11Biological Markers (Surrogate Marker)IBA
02/2015 - 06/2003
10Serotonin (5 Hydroxytryptamine)IBA
03/2015 - 10/2002
9N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
09/2014 - 06/2005
8Dopamine (Intropin)FDA LinkGeneric
12/2015 - 06/2005
8Glutamine (L-Glutamine)FDA Link
12/2015 - 01/2005
8tropisetron (Navoban)IBA
01/2015 - 07/2005
7Minocycline (Cyclops)FDA LinkGeneric
11/2015 - 09/2007
6D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA
06/2015 - 06/2005
6Amino AcidsFDA Link
01/2015 - 12/2006
6ifenprodilIBA
01/2015 - 06/2004
6KetamineFDA LinkGeneric
01/2014 - 02/2002
6Glutathione (Reduced Glutathione)IBA
10/2011 - 02/2002
5Antidepressive Agents (Antidepressants)IBA
01/2015 - 10/2002
4Formaldehyde (Formol)FDA Link
09/2012 - 01/2011
4Phencyclidine (Angel Dust)IBA
01/2012 - 02/2002
3Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
08/2015 - 04/2010
3LigandsIBA
02/2015 - 01/2006
3Clozapine (Clozaril)FDA LinkGeneric
10/2014 - 02/2003
3Risperidone (Risperdal Consta)FDA LinkGeneric
05/2014 - 01/2010
3Sarcosine (Methylglycine)IBA
08/2013 - 01/2010
3donepezil (Aricept)FDA LinkGeneric
04/2013 - 07/2009
3EnzymesIBA
01/2013 - 05/2008
3serine racemaseIBA
01/2013 - 06/2005
3Glycine Plasma Membrane Transport ProteinsIBA
04/2012 - 01/2006
3Epidermal Growth Factor (EGF)IBA
01/2012 - 06/2005
3Messenger RNA (mRNA)IBA
12/2010 - 06/2005
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2015 - 01/2011
2Oxytocin (Pitocin)FDA LinkGeneric
08/2015 - 01/2015
2Sodium BenzoateFDA Link
06/2015 - 01/2011
2Phosphotransferases (Kinase)IBA
02/2015 - 05/2009
2glycosylated serum albuminIBA
01/2015 - 01/2014
2Hemoglobins (Hemoglobin)IBA
01/2015 - 01/2014
2Glutamate Receptors (Glutamate Receptor)IBA
10/2014 - 06/2003
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
02/2014 - 11/2013
2olanzapine (Zyprexa)FDA Link
11/2013 - 01/2013
2Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
08/2013 - 02/2002
2HormonesIBA
04/2013 - 01/2012
2Carbon MonoxideIBA
09/2012 - 06/2005
2Morphine (MS Contin)FDA LinkGeneric
09/2012 - 01/2011
2Vincristine (Oncovin)FDA LinkGeneric
09/2012 - 07/2012
2Dactinomycin (Ac-De)FDA LinkGeneric
09/2012 - 07/2012
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
09/2012 - 07/2012
2Dopamine Receptors (Dopamine Receptor)IBA
09/2012 - 04/2009
2ParaffinIBA
01/2012 - 01/2012
2Cholinergic ReceptorsIBA
12/2011 - 02/2007
2cilostazol (Pletal)FDA LinkGeneric
10/2011 - 01/2011
2NicotineFDA Link
01/2011 - 07/2005
2gemcitabineFDA Link
07/2010 - 01/2009
2C-Reactive ProteinIBA
07/2010 - 01/2009
2Neurotransmitter Agents (Neurotransmitter)IBA
01/2010 - 01/2010
2Dizocilpine Maleate (Dizocilpine)IBA
01/2010 - 06/2004
2traxoprodil mesylateIBA
08/2009 - 06/2004

Therapy/Procedure

9Drug Therapy (Chemotherapy)
01/2015 - 03/2007
3Aftercare (After-Treatment)
01/2010 - 06/2005
2Stents
11/2015 - 01/2010
2Analgesia
09/2012 - 01/2011
2Radiotherapy
11/2011 - 08/2009