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Minoru Hasegawa Selected Research

Diffuse systemic sclerosis

4/2010Elevated serum concentrations of triggering receptor expressed on myeloid cells-1 in diffuse cutaneous systemic sclerosis: association with severity of pulmonary fibrosis.
1/2010Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis.
8/2004Improvement of skin sclerosis after occurrence of anticentromere antibody in a patient with diffuse cutaneous systemic sclerosis.
4/2003Function blocking autoantibodies against matrix metalloproteinase-1 in patients with systemic sclerosis.

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Minoru Hasegawa Research Topics

Disease

57Systemic Scleroderma (Systemic Sclerosis)
09/2015 - 06/2002
30Fibrosis (Cirrhosis)
06/2013 - 06/2002
14Pulmonary Fibrosis (Hamman Rich Syndrome)
05/2011 - 11/2002
12Dermatomyositis (Dermatopolymyositis)
01/2013 - 04/2003
12Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2011 - 04/2003
9Autoimmune Diseases (Autoimmune Disease)
06/2013 - 10/2005
8Sclerosis
02/2013 - 06/2002
7Hemorrhage
11/2012 - 03/2002
7Inflammation
05/2010 - 03/2002
5Ulcer
09/2015 - 12/2005
5Pain (Aches)
04/2015 - 09/2009
5Arthus Reaction
09/2012 - 03/2002
5Contact Dermatitis (Eczema, Contact)
06/2010 - 04/2003
4Bone Neoplasms (Bone Cancer)
04/2015 - 09/2009
4Hypersensitivity (Allergy)
04/2015 - 04/2003
4Myositis (Idiopathic Inflammatory Myopathies)
07/2014 - 02/2012
4Cicatrix (Scar)
09/2013 - 06/2004
4Graft vs Host Disease (Graft-Versus-Host Disease)
06/2013 - 01/2008
4Localized Scleroderma (Morphea)
10/2008 - 01/2003
3Neoplasms (Cancer)
11/2014 - 02/2012
3Hyperalgesia
01/2014 - 09/2009
3Interstitial Lung Diseases (Interstitial Lung Disease)
01/2014 - 04/2011
3Rheumatoid Arthritis
12/2012 - 02/2007
3Wounds and Injuries (Trauma)
11/2011 - 09/2007
3Lung Injury
09/2011 - 11/2002
3Edema
01/2010 - 03/2002
3Bullous Pemphigoid (Pemphigoid)
03/2008 - 11/2006
3Atopic Dermatitis (Atopic Eczema)
03/2008 - 04/2003
2Polymyositis
07/2014 - 05/2012
2Neuralgia (Stump Neuralgia)
01/2014 - 09/2009
2Telangiectasis (Telangiectasia)
11/2012 - 12/2008
2Osteoporosis
12/2010 - 02/2005
2Arthritis (Polyarthritis)
11/2010 - 01/2009
2Connective Tissue Diseases (Connective Tissue Disease)
03/2008 - 12/2007
2Psoriasis (Pustulosis Palmaris et Plantaris)
01/2008 - 05/2004
1Gangrene
09/2015
1Epilepsy (Aura)
07/2015
1Seizures (Seizure)
07/2015

Drug/Important Bio-Agent (IBA)

19AutoantibodiesIBA
09/2015 - 06/2002
14Immunoglobulin G (IgG)IBA
12/2012 - 12/2002
13Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
07/2014 - 03/2002
12CytokinesIBA
03/2013 - 11/2002
11Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2014 - 03/2002
11L-SelectinIBA
07/2014 - 03/2002
10AntibodiesIBA
09/2015 - 04/2005
10Interleukin-6 (Interleukin 6)IBA
12/2012 - 06/2002
9Bleomycin (Blenoxane)FDA LinkGeneric
11/2012 - 11/2002
7Type I DNA Topoisomerases (Topoisomerase I)IBA
09/2013 - 01/2004
7AntigensIBA
05/2011 - 07/2005
6Oxycodone (Oxycontin)FDA LinkGeneric
04/2015 - 09/2009
6Morphine (MS Contin)FDA LinkGeneric
04/2015 - 09/2009
6CollagenIBA
01/2013 - 04/2003
6ChemokinesIBA
01/2012 - 06/2004
6P-SelectinIBA
08/2010 - 09/2006
5Immunoglobulin M (IgM)IBA
12/2012 - 01/2004
5E-SelectinIBA
08/2010 - 09/2006
4InterferonsIBA
11/2014 - 06/2009
4Immunoglobulins (Immunoglobulin)IBA
12/2012 - 04/2006
4Interleukin-17 (Interleukin 27)IBA
11/2012 - 06/2008
4Antigen-Antibody Complex (Immune Complex)IBA
09/2012 - 05/2007
4Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
05/2011 - 06/2004
4Diffuse systemic sclerosisIBA
04/2010 - 04/2003
4Transforming Growth Factor beta (TGF-beta)IBA
01/2010 - 07/2004
3Idiopathic pulmonary hypertensionIBA
09/2015 - 01/2006
3Carbon MonoxideIBA
01/2014 - 07/2005
3Interleukin-10 (Interleukin 10)IBA
06/2013 - 08/2008
3Glycoproteins (Glycoprotein)IBA
12/2012 - 09/2007
3Interleukin-4 (Interleukin 4)IBA
11/2012 - 06/2008
3Immunoglobulin E (IgE)IBA
09/2012 - 06/2009
3trioctyl phosphine oxide (TOPO)IBA
01/2010 - 01/2004
3Hyaluronic Acid (Hyaluronan)IBA
08/2009 - 06/2008
3B-Cell Activating FactorIBA
03/2008 - 02/2007
3SelectinsIBA
09/2007 - 09/2006
2Messenger RNA (mRNA)IBA
07/2014 - 03/2013
2Opioid Receptors (Opioid Receptor)IBA
01/2014 - 01/2013
2OxygenIBA
01/2014 - 01/2011
2Fentanyl (Sublimaze)FDA LinkGeneric
01/2014 - 09/2009
2Chemokine CX3CL1IBA
03/2013 - 05/2004
2Biological Markers (Surrogate Marker)IBA
02/2013 - 05/2011
2MicroRNAs (MicroRNA)IBA
01/2013 - 04/2012
2Opioid Analgesics (Opioids)IBA
01/2013 - 09/2009
2EnzymesIBA
01/2013 - 01/2010
2Anticardiolipin AntibodiesIBA
12/2012 - 09/2007
2Transforming Growth Factors (Transforming Growth Factor)IBA
11/2012 - 01/2012
2trinitrophenyl-bovine serum albuminIBA
09/2012 - 06/2009
2Mi-2 antibodiesIBA
04/2011 - 12/2005
2Interleukin-8 (Interleukin 8)IBA
02/2011 - 07/2003
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
02/2011 - 01/2008
2Inosine Triphosphate (ITP)IBA
12/2010 - 02/2005
2SteroidsIBA
12/2010 - 09/2003
2Prednisolone (Predate)FDA LinkGeneric
01/2010 - 08/2004
2Toll-Like Receptors (Toll-Like Receptor)IBA
08/2009 - 06/2008
2Interleukin-12 (IL 12)IBA
07/2009 - 02/2006
2Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
10/2008 - 04/2003
2Chemotactic FactorsIBA
06/2004 - 07/2003
1Anticonvulsants (Antiepileptic Drugs)IBA
07/2015
1CalciumIBA
07/2015
1RNA Polymerase IIIIBA
04/2015
1polyglycerolIBA
07/2014

Therapy/Procedure

2Hematopoietic Stem Cell Transplantation
04/2013 - 01/2008