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Ronald Gust Selected Research

ethylenediamine (ethylenediamine dihydroiodide)

4/2008Biological effect of mono- and dinuclear alkylamine platinum(II) compounds on human lymphoma cells.
5/2006Dinuclear alkylamine platinum(II) complexes of [1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II): influence of endocytosis and copper and organic cation transport systems on cellular uptake.
11/2005[N-ethyl- and [N,N'-diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)-ethylenediamine]dichloroplatinum(II): structure and cytotoxic/estrogenic activity in breast cancer cells.
6/2004[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action I: antitumor activity due to the reduction of the endogenous estrogen level.
6/2004[1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity.

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Ronald Gust Research Topics

Disease

38Breast Neoplasms (Breast Cancer)
02/2022 - 08/2002
33Neoplasms (Cancer)
07/2022 - 03/2004
15Carcinoma (Carcinomatosis)
02/2022 - 02/2007
10Leukemia
03/2021 - 03/2004
9Lymphoma (Lymphomas)
10/2013 - 03/2004
6BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
04/2021 - 11/2006
4Colonic Neoplasms (Colon Cancer)
10/2011 - 04/2008
3Necrosis
03/2011 - 04/2008
3Prostatic Neoplasms (Prostate Cancer)
03/2007 - 12/2004
2Neoplasm Metastasis (Metastasis)
01/2020 - 12/2008
2Neuroblastoma
01/2020 - 12/2019
2Carcinogenesis
11/2019 - 12/2008
2Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2011 - 04/2008
1Ovarian Neoplasms (Ovarian Cancer)
05/2020
1Hemolysis
01/2020
1Liver Neoplasms (Liver Cancer)
01/2020
1Malignant Mesothelioma
12/2013
1Insulin Resistance
11/2012
1Diabetes Mellitus
11/2012
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
10/2010
1Alzheimer Disease (Alzheimer's Disease)
08/2010

Drug/Important Bio-Agent (IBA)

13PlatinumIBA
07/2022 - 06/2004
10LigandsIBA
01/2020 - 03/2004
9Cisplatin (Platino)FDA LinkGeneric
02/2022 - 01/2007
9Pharmaceutical PreparationsIBA
04/2021 - 06/2004
6Imatinib Mesylate (Gleevec)FDA Link
04/2021 - 11/2006
6Biological ProductsIBA
07/2012 - 02/2007
6Estrogen ReceptorsIBA
11/2011 - 08/2002
6Hormones (Hormone)IBA
03/2009 - 04/2003
5GoldIBA
07/2022 - 05/2007
5Coordination ComplexesIBA
07/2022 - 03/2007
5Estrogens (Estrogen)FDA Link
04/2020 - 06/2004
5DNA (Deoxyribonucleic Acid)IBA
01/2020 - 06/2004
5ethylenediamine (ethylenediamine dihydroiodide)FDA Link
04/2008 - 06/2004
4IronIBA
12/2019 - 11/2009
4IsoenzymesIBA
11/2019 - 10/2010
4Cytostatic AgentsIBA
10/2010 - 01/2007
4LuciferasesIBA
11/2005 - 08/2002
3CobaltIBA
02/2022 - 03/2004
3Alkynes (Acetylenes)IBA
02/2022 - 03/2004
3Dendrimers (Dendrons)IBA
11/2020 - 04/2008
3Peptides (Polypeptides)IBA
10/2020 - 07/2010
3PPAR gammaIBA
01/2020 - 11/2012
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
12/2013 - 10/2010
3Fluorouracil (Carac)FDA LinkGeneric
10/2012 - 04/2008
3Estrogen Receptor alphaIBA
07/2010 - 02/2004
3DiaminesIBA
06/2006 - 06/2004
3Estradiol (Delestrogen)FDA LinkGeneric
10/2003 - 08/2002
2Arachidonic Acid (Vitamin F)IBA
02/2022 - 10/2010
2Drug CarriersIBA
11/2020 - 05/2011
2EstersIBA
01/2020 - 11/2006
2Telmisartan (Micardis)FDA Link
01/2020 - 05/2008
2Proteins (Proteins, Gene)FDA Link
01/2015 - 11/2005
2propynyl benzoateIBA
12/2013 - 04/2005
2AcidsIBA
07/2011 - 11/2006
2Melphalan (Alkeran)FDA LinkGeneric
05/2011 - 10/2010
2Bendamustine HydrochlorideFDA Link
05/2011 - 10/2010
2MetalsIBA
04/2011 - 03/2007
2RhodiumIBA
03/2011 - 02/2009
2Propidium (Propidium Iodide)IBA
03/2011 - 07/2010
2Prostaglandins EIBA
11/2010 - 10/2010
2Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
02/2009 - 05/2006
2Transforming Growth Factor beta (TGF-beta)IBA
12/2008 - 03/2006
2NucleosidesIBA
01/2008 - 04/2007
2Carboplatin (JM8)FDA LinkGeneric
03/2007 - 01/2007
2ethyleneIBA
06/2004 - 06/2004
1EnzymesIBA
02/2022
1Cholecystokinin B ReceptorIBA
10/2020
1minigastrinIBA
10/2020
1Angiotensin II Type 1 Receptor BlockersIBA
06/2020
1Auranofin (Ridaura)FDA Link
05/2020
1Selective Estrogen Receptor Modulators (SERM)IBA
04/2020
1Aromatase InhibitorsIBA
04/2020
1indoleIBA
01/2020
1Antineoplastic Agents (Antineoplastics)IBA
01/2020
1Transcription Factors (Transcription Factor)IBA
01/2020
1CarbenoxoloneIBA
01/2020
1MicellesIBA
01/2020
1LipidsIBA
12/2019
1FluorineIBA
01/2015
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
12/2013
1Methanol (Carbinol)IBA
12/2013
1Hydroxyl RadicalIBA
10/2013
1ScopoletinIBA
08/2012
1SilverIBA
12/2011
1Nitric Oxide DonorsIBA
08/2011
1licofeloneIBA
08/2011
1Dasatinib (BMS 354825)FDA Link
07/2011
1salophenIBA
04/2011
1ManganeseIBA
04/2011
1Schiff Bases (Schiff Base)IBA
04/2011
1ProstaglandinsIBA
11/2010
1Iron(III)-salopheneIBA
11/2010
1benzamideIBA
10/2010
1Dinoprostone (PGE2)FDA Link
10/2010
1Amino AcidsFDA Link
08/2010
1Peptide Hydrolases (Proteases)FDA Link
07/2010
1Annexin A5IBA
07/2010

Therapy/Procedure

11Therapeutics
04/2021 - 06/2004
2Drug Therapy (Chemotherapy)
07/2022 - 03/2007