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Wolfgang L Gross Selected Research

Myeloblastin (Proteinase 3)

4/2015Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis: challenges and solutions 2014.
7/2012Genetically distinct subsets within ANCA-associated vasculitis.
1/2011Distinct proteinase 3-induced cytokine patterns in Wegener´s granulomatosis, Churg-Strauss syndrome, and healthy controls.
8/2010Clinical manifestations and treatment of Wegener's granulomatosis.
1/2010Membrane proteinase 3 (mPR3) expression on neutrophils is not increased in localized Wegener's granulomatosis (WG) and Churg-Strauss syndrome (CSS).
1/2010Clinical and immunological features of drug-induced and infection-induced proteinase 3-antineutrophil cytoplasmic antibodies and myeloperoxidase-antineutrophil cytoplasmic antibodies and vasculitis.
1/2010The role of proteinase 3 (PR3) and the protease-activated receptor-2 (PAR-2) pathway in dendritic cell (DC) maturation of human-DC-like monocytes and murine DC.
9/2007Current state of biologicals in the management of systemic vasculitis.
6/2006Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway.
2/2004Frequency of proteinase 3 (PR3)-specific autoreactive T cells determined by cytokine flow cytometry in Wegener's granulomatosis.
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Wolfgang L Gross Research Topics

Disease

30Wegener Granulomatosis (Wegener's Granulomatosis)
01/2014 - 05/2002
28Vasculitis (Vasculitides)
05/2014 - 07/2003
13Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
04/2015 - 03/2006
12Churg-Strauss Syndrome (Allergic Angiitis)
05/2013 - 05/2002
7Microscopic Polyangiitis
07/2014 - 02/2005
7Systemic Vasculitis
05/2013 - 05/2002
6Inflammation
11/2013 - 04/2004
6Infection
07/2013 - 08/2002
6Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2013 - 08/2002
6Rheumatoid Arthritis
05/2013 - 08/2002
5Autoimmune Diseases (Autoimmune Disease)
01/2014 - 01/2003
3Giant Cell Arteritis (Horton Disease)
05/2013 - 01/2012
3Granuloma
02/2011 - 06/2006
3Eosinophilia
11/2010 - 01/2004
2Takayasu Arteritis (Arteritis, Takayasu's)
05/2013 - 01/2012
2Asthma (Bronchial Asthma)
11/2009 - 01/2004
2Neutropenia
09/2002 - 08/2002
2Felty's Syndrome (Syndrome, Felty's)
09/2002 - 08/2002
1Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis)
05/2013
1Multiple Myeloma
07/2011
1Hypereosinophilic Syndrome (Loeffler Endocarditis)
11/2010
1Immune System Diseases (Immune Disorders)
05/2010
1Leukopenia
05/2009
1Pneumonia (Pneumonitis)
01/2009
1Schnitzler Syndrome
08/2008
1Arteritis
03/2006
1Vascular Diseases (Vascular Disease)
02/2006
1Hashimoto Disease (Thyroiditis, Hashimoto)
12/2005
1Ulcerative Colitis
11/2004
1Crohn Disease (Crohn's Disease)
11/2004
1Anemia
11/2004
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
11/2004
1Rare Diseases (Rare Disease)
06/2004
1Glomerulonephritis
04/2004
1Cystic Fibrosis (Mucoviscidosis)
02/2004
1Ankylosing Spondylitis
10/2003

Drug/Important Bio-Agent (IBA)

28Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
04/2015 - 07/2003
13AutoantibodiesIBA
04/2015 - 05/2002
12Myeloblastin (Proteinase 3)IBA
04/2015 - 02/2004
11glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2014 - 01/2004
10Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2012 - 06/2002
8AntibodiesIBA
01/2014 - 05/2002
5Methotrexate (Mexate)FDA LinkGeneric
07/2014 - 06/2002
3Peroxidase (Myeloperoxidase)IBA
04/2015 - 01/2010
3Azathioprine (Imuran)FDA LinkGeneric
07/2014 - 01/2006
3rituximab (Mabthera)FDA Link
03/2012 - 04/2006
3AntigensIBA
02/2011 - 06/2004
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2007 - 12/2002
3Adrenal Cortex Hormones (Corticosteroids)IBA
06/2004 - 01/2004
2leflunomide (Arava)FDA LinkGeneric
07/2014 - 01/2006
2Prednisolone (Predate)FDA LinkGeneric
03/2012 - 08/2005
2N 30IBA
01/2010 - 02/2004
2Carbon MonoxideIBA
01/2010 - 06/2004
2Interferon-alpha (Interferon Alfa)FDA Link
01/2010 - 04/2007
2GlucocorticoidsIBA
01/2009 - 06/2002
2Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
08/2008 - 10/2003
2Antigen-Antibody Complex (Immune Complex)IBA
03/2006 - 05/2002
2Immunoglobulin G (IgG)IBA
11/2004 - 09/2002
2TNFR-Fc fusion protein (etanercept)FDA Link
01/2004 - 10/2003
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
09/2002 - 08/2002
1mycophenolate mofetil (Cellcept)FDA LinkGeneric
07/2014
1LigandsIBA
07/2013
1Glycoproteins (Glycoprotein)IBA
05/2013
1Complementary DNA (cDNA)IBA
05/2013
1C-Reactive ProteinIBA
03/2012
1bortezomib (Velcade)FDA Link
07/2011
1Immunoglobulins (Immunoglobulin)IBA
02/2011
1Monoclonal AntibodiesIBA
02/2011
1Immunoglobulin E (IgE)IBA
11/2010
1GhrelinIBA
05/2010
1LeptinIBA
05/2010
1Leptin ReceptorsIBA
05/2010
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2010
1Serine Proteases (Serine Protease)IBA
01/2010
1SuperantigensIBA
01/2010
1flt3 ligand protein (flt3 ligand)IBA
01/2010
1PAR-2 ReceptorIBA
01/2010
1Recombinant Interferon Type IIBA
01/2010
1CytokinesIBA
12/2009
1Immunologic Factors (Immunomodulators)IBA
12/2009
1DNA (Deoxyribonucleic Acid)IBA
06/2009
1Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric
01/2009
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2009
1Interleukin-1 (Interleukin 1)IBA
08/2008
1Interleukin-15 (Interleukin 15)IBA
05/2008
1Biological Markers (Surrogate Marker)IBA
05/2007
1CollagenIBA
02/2006
1infliximab (Remicade)FDA Link
01/2006
1Tyrosine (L-Tyrosine)FDA Link
12/2005
1Phospholipases (Phospholipase)IBA
01/2005
1PeptidesIBA
11/2004
1bactericidal permeability increasing proteinIBA
11/2004
1Trimethoprim (Proloprim)FDA LinkGeneric
01/2004
1SulfamethoxazoleFDA LinkGeneric
01/2004

Therapy/Procedure

6Remission Induction
01/2012 - 06/2002
1Transplantation (Transplant Recipients)
05/2012
1Chemoprevention
01/2009
1Biological Therapy
04/2007
1Heterologous Transplantation (Xenotransplantation)
11/2004
1Drug Therapy (Chemotherapy)
01/2004