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Mihai Gheorghiade Selected Research

Vasopressin Receptors (Arginine Vasopressin Receptor)

6/2013Clinical course of patients with hyponatremia and decompensated systolic heart failure and the effect of vasopressin receptor antagonism with tolvaptan.
8/2010Vasopressin receptor antagonists for the treatment of hyponatremia: systematic review and meta-analysis.
5/2010Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction: results from Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) program.
11/2008Acute hemodynamic effects of tolvaptan, a vasopressin V2 receptor blocker, in patients with symptomatic heart failure and systolic dysfunction: an international, multicenter, randomized, placebo-controlled trial.
3/2007Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial.
6/2006The clinical effects of vasopressin receptor antagonists in heart failure.
5/2006Tolvaptan: a selective vasopressin type 2 receptor antagonist in congestive heart failure.
12/2005Overview of vasopressin receptor antagonists in heart failure resulting in hospitalization.

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Mihai Gheorghiade Research Topics

Disease

208Heart Failure
12/2015 - 01/2002
20Hyponatremia
06/2013 - 06/2003
18Myocardial Infarction
07/2015 - 01/2003
17Atrial Fibrillation
06/2015 - 01/2002
12Body Weight (Weight, Body)
07/2012 - 06/2003
10Hypotension (Low Blood Pressure)
10/2013 - 03/2002
7Systolic Heart Failure
08/2013 - 01/2002
7Dyspnea (Shortness of Breath)
06/2013 - 03/2007
6Acute Coronary Syndrome
02/2016 - 10/2002
6Coronary Artery Disease (Coronary Atherosclerosis)
07/2015 - 05/2003
6Cardiomyopathies (Cardiomyopathy)
07/2011 - 03/2003
6Edema
06/2011 - 06/2003
6Left Ventricular Dysfunction
04/2010 - 03/2002
5Diabetes Mellitus
09/2014 - 07/2011
5Cardiac Sudden Death (Sudden Cardiac Arrest)
09/2011 - 08/2005
4Kidney Diseases (Kidney Disease)
02/2015 - 11/2011
4Hypertension (High Blood Pressure)
01/2015 - 06/2009
4Inflammation
09/2013 - 02/2008
3Hypokalemia
03/2015 - 04/2004
3Anemia
05/2014 - 09/2003
3Low Cardiac Output
09/2013 - 12/2006
3Cardiac Arrhythmias (Arrythmia)
05/2013 - 07/2011
3Systemic Scleroderma (Systemic Sclerosis)
03/2013 - 08/2011
3Renal Insufficiency (Renal Failure)
03/2013 - 05/2006
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
02/2011 - 04/2004
2Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
09/2015 - 01/2015
2Stroke (Strokes)
07/2015 - 11/2013
2Hyperkalemia
03/2015 - 03/2013
2Thrombophilia
09/2013 - 02/2011
2Albuminuria
08/2013 - 06/2012
2Weight Loss (Weight Reduction)
06/2013 - 06/2006
2Respiratory Sounds (Crackle)
04/2013 - 04/2010
2Ventricular Remodeling
03/2013 - 02/2008
2Disease Progression
03/2013 - 08/2011
2Necrosis
09/2012 - 05/2008
2Chronic Obstructive Pulmonary Disease (COPD)
07/2012 - 04/2012
2Liver Diseases (Liver Disease)
03/2012 - 10/2008

Drug/Important Bio-Agent (IBA)

53Vasopressins (Vasopressin)IBA
10/2015 - 06/2003
46tolvaptanFDA Link
10/2015 - 02/2003
20SodiumIBA
01/2015 - 06/2003
18Digoxin (Digitek)FDA LinkGeneric
06/2015 - 01/2002
16AldosteroneIBA
11/2013 - 08/2005
15Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
06/2013 - 05/2006
12Brain Natriuretic Peptide (Natrecor)FDA Link
07/2015 - 02/2003
12Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2013 - 01/2002
11AngiotensinsIBA
03/2013 - 01/2007
10Milrinone (Primacor)FDA LinkGeneric
05/2008 - 03/2002
9Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
02/2015 - 02/2011
8Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
06/2013 - 12/2005
8DiureticsIBA
06/2013 - 01/2002
8Arginine Vasopressin (Argipressin)IBA
01/2013 - 07/2003
8carvedilol (Coreg)FDA LinkGeneric
01/2007 - 01/2002
7eplerenone (Inspra)FDA LinkGeneric
02/2015 - 08/2005
7Biological Markers (Surrogate Marker)IBA
10/2013 - 06/2002
7Angiotensin Receptor AntagonistsIBA
05/2013 - 05/2006
73- ((2- aminoethoxy)imino)androstane- 6,17- dioneIBA
08/2011 - 01/2007
7DobutamineFDA LinkGeneric
05/2008 - 02/2003
6Guanylate Cyclase (Guanylyl Cyclase)IBA
12/2015 - 12/2009
6CreatinineIBA
01/2015 - 12/2006
6Carbon MonoxideIBA
09/2014 - 09/2003
5aliskirenFDA Link
06/2015 - 01/2011
5HormonesIBA
12/2011 - 04/2003
4PotassiumIBA
09/2015 - 06/2007
4pro-brain natriuretic peptide (1-76)IBA
02/2015 - 06/2009
4Amino AcidsFDA Link
01/2015 - 04/2003
4Hemoglobins (Hemoglobin)IBA
12/2014 - 01/2008
4AdenosineFDA LinkGeneric
10/2013 - 08/2010
4NitrogenIBA
07/2012 - 12/2006
4Urea (Carbamide)FDA LinkGeneric
07/2012 - 12/2006
4tezosentanIBA
06/2004 - 10/2002
3CollagenIBA
11/2015 - 02/2008
3Natriuretic PeptidesIBA
10/2015 - 10/2011
3rivaroxabanIBA
07/2015 - 02/2011
3Warfarin (Coumadin)FDA LinkGeneric
11/2013 - 05/2003
3Hydralazine (Apresoline)FDA LinkGeneric
06/2013 - 05/2003
3Aldosterone AntagonistsIBA
02/2013 - 08/2008
3BAY 58-2667IBA
01/2013 - 12/2009
3Neurotransmitter Agents (Neurotransmitter)IBA
09/2012 - 01/2007
3Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
09/2011 - 02/2009
2ivabradineIBA
03/2015 - 01/2014
2Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA
01/2015 - 05/2009
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2013 - 02/2010
2Spironolactone (Aldactone)FDA LinkGeneric
08/2013 - 06/2012
2NitratesIBA
06/2013 - 05/2009
2IronIBA
03/2013 - 02/2013
2GadoliniumIBA
01/2013 - 10/2003
2TroponinIBA
09/2012 - 09/2010
2Amiodarone (Amiodarona)FDA LinkGeneric
09/2011 - 05/2003

Therapy/Procedure

16Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
08/2014 - 05/2003
15Cardiac Resynchronization Therapy
08/2014 - 03/2004
5Length of Stay
10/2015 - 07/2004
4Transplants (Transplant)
08/2011 - 07/2006
3Therapeutics
10/2013 - 01/2008
3Liver Transplantation
07/2011 - 11/2007
2Patient Readmission
08/2013 - 01/2007
2Drug Therapy (Chemotherapy)
08/2013 - 07/2003
2Catheters
04/2013 - 10/2007
2Stem Cell Transplantation
03/2013 - 08/2011
2Transplantation (Transplant Recipients)
03/2013 - 01/2008
2Electric Countershock (Cardioversion)
09/2011 - 05/2004