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Thomas W Geisbert Selected Research

Vesicular Stomatitis

10/2015A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs.
10/2015Stat1-Deficient Mice Are Not an Appropriate Model for Efficacy Testing of Recombinant Vesicular Stomatitis Virus-Based Filovirus Vaccines.
10/2015Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus.
4/2015Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus.
4/2015Safety of recombinant VSV-Ebola virus vaccine vector in pigs.
2/2015Vesicular stomatitis virus-based vaccines against Lassa and Ebola viruses.
1/2014Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates.
1/2013Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates.
1/2013Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus.
1/2013Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease.
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Thomas W Geisbert Research Topics

Disease

42Infection
10/2015 - 02/2002
23Vesicular Stomatitis
10/2015 - 06/2005
7Fever (Fevers)
07/2013 - 12/2003
3Disseminated Intravascular Coagulation
10/2015 - 08/2005
3Marburg Virus Disease
10/2015 - 02/2007
3Viral Hemorrhagic Fevers (Viral Hemorrhagic Fever)
02/2015 - 06/2006
3Ebola Hemorrhagic Fever
11/2011 - 12/2003
2Viremia
10/2015 - 01/2010
2Lassa Fever (Fever, Lassa)
01/2015 - 06/2005
2Disease Progression
10/2010 - 03/2007
2Smallpox (Variola)
10/2004 - 01/2004
1Paramyxoviridae Infections (Parainfluenza)
08/2015
1Epidemic Louse-Borne Typhus (Typhus)
02/2015
1Human Influenza (Influenza)
01/2015
1Leukemia
01/2014
1Neoplasms (Cancer)
01/2014
1Nervous System Diseases (Neurological Disorders)
01/2013
1Virus Diseases (Viral Diseases)
08/2012
1Sepsis (Septicemia)
11/2007
1Communicable Diseases (Infectious Diseases)
01/2007
1Inflammation
08/2005
1Edema
06/2005
1Severe Acute Respiratory Syndrome
10/2003

Drug/Important Bio-Agent (IBA)

25Glycoproteins (Glycoprotein)IBA
10/2015 - 06/2005
17VaccinesIBA
10/2015 - 06/2005
4FibrinIBA
10/2015 - 11/2007
4Thromboplastin (Tissue Factor)IBA
11/2007 - 12/2003
3Protein CIBA
10/2015 - 12/2003
3CytokinesIBA
10/2015 - 03/2002
3Ribavirin (Virazole)FDA LinkGeneric
01/2015 - 10/2010
3AntigensIBA
01/2013 - 10/2010
2GTP-Binding Proteins (G-Protein)IBA
10/2015 - 01/2013
2Small Interfering RNA (siRNA)IBA
08/2014 - 02/2014
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2010 - 10/2004
2DNA (Deoxyribonucleic Acid)IBA
10/2010 - 01/2004
2EnzymesIBA
05/2010 - 06/2005
2Factor VIIa (Activated Factor VII)IBA
11/2007 - 12/2003
2RNA (Ribonucleic Acid)IBA
06/2006 - 12/2003
2ChemokinesIBA
08/2005 - 03/2002
1Fibrinogen (Factor I)FDA Link
10/2015
1salicylhydroxamic acid (SHAM)IBA
10/2015
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2015
1Proteins (Proteins, Gene)IBA
10/2015
1Immunoglobulin M (IgM)IBA
02/2015
1tebufenozide (Mimic)IBA
02/2015
1Immunoglobulin G (IgG)IBA
02/2015
16-fluoro-3-hydroxy-2-pyrazinecarboxamideIBA
01/2015
1myocardinIBA
01/2014
1Messenger RNA (mRNA)IBA
01/2014
1CCAAT-Enhancer-Binding Protein-alphaIBA
01/2014
1Ebola virus nucleoprotein VP35IBA
07/2013
1InterferonsIBA
07/2013
1attachment protein GIBA
01/2013
1Ebola VaccinesIBA
11/2011
1DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA
11/2011
1Capsid Proteins (Capsid Protein)IBA
04/2011
1Interferon-gamma (Interferon, gamma)IBA
10/2010
1Viral RNAIBA
01/2010
1Interleukin-6 (Interleukin 6)IBA
09/2008
1AntibodiesIBA
11/2007
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
11/2007
1drotrecogin alfa activated (Xigris)FDA Link
11/2007
1deoxyuridine triphosphateIBA
11/2007
1Fc Receptors (Fc Receptor)IBA
11/2007
1Complement System Proteins (Complement)IBA
11/2007
1enhanced green fluorescent proteinIBA
11/2007
1EpitopesIBA
11/2007
1FurinIBA
03/2007
1tumor necrosis factor-alpha convertaseIBA
01/2007
1Neutralizing AntibodiesIBA
01/2007
1Oligonucleotide ProbesIBA
01/2007
1NF-kappa B (NF-kB)IBA
10/2004
1Complementary DNA (cDNA)IBA
10/2003
1Free RadicalsIBA
03/2002
1OxygenIBA
03/2002
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2002
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
03/2002
1Blocking AntibodiesIBA
02/2002

Therapy/Procedure

7Therapeutics
10/2015 - 03/2002