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Pierluigi Gambetti Selected Research

Acquired CJD

1/2015Distinct pathological phenotypes of Creutzfeldt-Jakob disease in recipients of prion-contaminated growth hormone.
11/2014R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia.
12/2005Creutzfeldt-Jakob disease (CJD) with a mutation at codon 148 of prion protein gene: relationship with sporadic CJD.
12/2004Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine.
7/2004Targeting prion amyloid deposits in vivo.
1/2003Sporadic and familial CJD: classification and characterisation.

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Pierluigi Gambetti Research Topics

Disease

26Prion Diseases (Transmissible Spongiform Encephalopathies)
10/2015 - 12/2002
18Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
06/2015 - 03/2003
6Scrapie
06/2015 - 02/2004
4Fatal Familial Insomnia
03/2006 - 12/2002
4Alzheimer Disease (Alzheimer's Disease)
10/2005 - 03/2003
3Infection
01/2005 - 12/2004
3Sleep Initiation and Maintenance Disorders (Insomnia)
01/2005 - 01/2003
2Frontotemporal Dementia
11/2014 - 02/2004
1Bovine Spongiform Encephalopathy (Mad Cow Disease)
06/2015
1Kuru
01/2015
1Myoclonus (Nocturnal Myoclonus)
09/2011
1Dementia (Dementias)
09/2011
1Akinetic Mutism (Coma Vigil)
09/2011
1Muscular Diseases (Myopathy)
04/2007
1Fibrosis (Cirrhosis)
04/2007
1Down Syndrome (Down's Syndrome)
01/2006
1Neurodegenerative Diseases (Neurodegenerative Disease)
09/2005
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
09/2005
1Parkinson Disease (Parkinson's Disease)
09/2005
1HIV Infections (HIV Infection)
10/2004
1Amyloid Plaque
07/2004
1Sleep Disorders
12/2002

Drug/Important Bio-Agent (IBA)

14Codon (Codons)IBA
01/2015 - 12/2002
10PrionsIBA
06/2015 - 04/2003
9Valine (L-Valine)FDA Link
01/2015 - 01/2005
6Methionine (L-Methionine)FDA Link
01/2015 - 01/2005
6Acquired CJDIBA
01/2015 - 01/2003
6Endopeptidase K (Proteinase K)IBA
03/2013 - 10/2003
4PrPSc ProteinsIBA
01/2013 - 12/2004
4Amyloid (Amyloid Fibrils)IBA
10/2009 - 07/2004
3Carbon MonoxideIBA
01/2011 - 11/2007
3Detergents (Detergent)IBA
05/2010 - 01/2005
2Glutamic Acid (Glutamate)FDA Link
01/2013 - 10/2004
2Staphylococcal Protein A (A, Protein)IBA
05/2010 - 02/2004
1Mitochondrial DNA (mtDNA)IBA
10/2015
1Growth Hormone (Somatotropin)IBA
01/2015
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2013
1Isoleucine (L-Isoleucine)FDA Link
01/2013
1tranilast (N 5')IBA
09/2011
1SaltsIBA
05/2010
1AntibodiesIBA
10/2009
1Protein Isoforms (Isoforms)IBA
04/2008
1Doxycycline (Vibramycin)FDA LinkGeneric
04/2007
1Glucose (Dextrose)FDA LinkGeneric
03/2006
1Deoxyglucose (2 Deoxy D glucose)IBA
03/2006
1Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA
01/2006
18-hydroxyguanosineIBA
09/2005
1Heme Oxygenase-1IBA
09/2005
1EpitopesIBA
01/2005
1Biological Markers (Surrogate Marker)IBA
12/2004
1HLA-DR Antigens (HLA-DR)IBA
10/2004
1methionylmethionine (Met-Met)IBA
10/2004
1Glutathione (Reduced Glutathione)IBA
10/2004
1Caspase 3 (Caspase-3)IBA
10/2004
1Interleukin-1 (Interleukin 1)IBA
10/2004
1Excitatory Amino AcidsIBA
10/2004
11,4- bis(4'- hydroxystyryl)- 2- methoxybenzeneIBA
07/2004
1LigandsIBA
07/2004
1DNA-Binding Proteins (DNA Binding Protein)IBA
02/2004
1DNA (Deoxyribonucleic Acid)IBA
02/2004
1A-Form DNA (A-DNA)IBA
02/2004
1AS 8IBA
02/2004
1Amyloid beta-PeptidesIBA
02/2004
1urinary gonadotropin fragmentIBA
10/2003
1Proteins (Proteins, Gene)IBA
12/2002

Therapy/Procedure

1Therapeutics
01/2005