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Kohji Fukunaga Selected Research

spiro(imidazo- (1,2- a)pyridine- 3,2- indan)- 2(3H)- one

7/2008Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) treatment rescues olfactory bulbectomy-induced memory impairment by activating Ca2+/calmodulin kinase II and protein kinase C in mouse hippocampus.

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Kohji Fukunaga Research Topics

Disease

34Ischemia
10/2015 - 08/2002
21Hypertrophy
01/2014 - 12/2007
17Brain Ischemia (Cerebral Ischemia)
10/2015 - 07/2005
10Embolism (Embolus)
01/2012 - 09/2005
9Cardiomegaly (Heart Hypertrophy)
01/2014 - 01/2009
7Alzheimer Disease (Alzheimer's Disease)
03/2014 - 02/2007
7Heart Failure
01/2014 - 05/2009
7Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2013 - 09/2003
6Myocardial Infarction
01/2012 - 12/2004
5Cardiovascular Diseases (Cardiovascular Disease)
07/2013 - 01/2008
5Aortic Valve Stenosis (Aortic Stenosis)
08/2011 - 12/2007
5Myocardial Ischemia (Ischemic Heart Diseases)
05/2009 - 10/2007
4Memory Disorders (Memory Loss)
10/2015 - 07/2008
4Schizophrenia (Dementia Praecox)
04/2011 - 09/2006
4Brain Edema (Cerebral Edema)
10/2009 - 10/2006
4Reperfusion Injury
01/2008 - 12/2004
3Neurodegenerative Diseases (Neurodegenerative Disease)
10/2013 - 06/2011
3Hypertension (High Blood Pressure)
01/2012 - 05/2009
3Body Weight (Weight, Body)
12/2011 - 12/2007
3Intracranial Embolism
10/2009 - 09/2005
2Glioma (Gliomas)
01/2013 - 05/2003
2Neoplasms (Cancer)
01/2013 - 07/2003
2Vascular System Injuries
01/2013 - 01/2011
2Vascular Diseases (Vascular Disease)
01/2013 - 05/2009
2Learning Disorders (Learning Disability)
02/2012 - 04/2006
2X-Linked Mental Retardation (Mental Retardation, X Linked)
06/2011 - 01/2011
2Thalassemia
06/2011 - 01/2011
2Catalepsy
04/2011 - 02/2010
2Neuroblastoma
02/2010 - 10/2009
2Huntington Disease (Huntington's Disease)
12/2009 - 04/2009
2Infarction
06/2005 - 12/2004
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
12/2014
1Autistic Disorder (Autism)
01/2014
1Experimental Diabetes Mellitus
05/2013

Drug/Important Bio-Agent (IBA)

13Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
10/2015 - 09/2002
9sigma-1 receptor (receptor 1, sigma)IBA
10/2015 - 11/2009
9Fas Ligand Protein (Fas Ligand)IBA
01/2012 - 08/2002
93- (2- (4- (3- chloro- 2- methylphenyl)1- piperazinyl)ethyl)5,6- dimethoxy- 1- (4- imidazolylmethyl)- 1H- indazol dihydrochloride 3.5 hydrateIBA
02/2010 - 09/2004
7Phosphotransferases (Kinase)IBA
01/2013 - 08/2002
6CalcineurinIBA
01/2011 - 07/2006
6Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
01/2010 - 03/2004
6Vanadates (Orthovanadate)IBA
09/2006 - 08/2002
6SodiumIBA
09/2006 - 08/2002
5Adenosine Triphosphate (ATP)IBA
10/2015 - 06/2011
5Fluvoxamine (Luvox)FDA LinkGeneric
01/2014 - 10/2010
5Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2013 - 09/2005
5Proteins (Proteins, Gene)IBA
08/2011 - 07/2003
5CalpainIBA
01/2011 - 05/2006
5Calmodulin (Calcium-Dependent Activator Protein)IBA
01/2011 - 06/2005
5Tyrosine (L-Tyrosine)FDA Link
01/2008 - 06/2005
4Dehydroepiandrosterone (DHEA)IBA
10/2015 - 11/2009
4Angiotensin IIIBA
01/2014 - 12/2007
4MelatoninIBA
01/2014 - 04/2011
4oxovanadium IVIBA
01/2012 - 10/2008
4Vanadium CompoundsIBA
05/2009 - 03/2008
3SA 4503IBA
01/2014 - 01/2013
3Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2013 - 11/2010
3Peroxynitrous Acid (Peroxynitrite)IBA
02/2012 - 04/2007
3Calcium-Calmodulin-Dependent Protein KinasesIBA
05/2010 - 09/2006
3DystrophinIBA
02/2010 - 12/2007
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2009 - 11/2003
3Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2008 - 09/2006
3Transcription Factors (Transcription Factor)IBA
09/2007 - 08/2002
23-nitrotyrosineIBA
04/2013 - 04/2011
2nobiletinIBA
01/2013 - 10/2009
2VanadiumIBA
01/2012 - 05/2009
2Haloperidol (Haldol)FDA LinkGeneric
04/2011 - 02/2010
2Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
04/2011 - 09/2006
2N-Methylaspartate (NMDA)IBA
01/2011 - 02/2007
2Estrogens (Estrogen)FDA Link
01/2010 - 12/2007
23-nitropropionic acidIBA
12/2009 - 04/2009
2Protein Tyrosine PhosphatasesIBA
05/2009 - 10/2008
2CytokinesIBA
01/2009 - 09/2006
23- (2- (4- (3- chloro- 2- methylphenyl)- 1- piperazinyl)ethyl)- 5,6- dimethoxyindazoleIBA
01/2009 - 12/2007
2Endothelin-1 (Endothelin 1)IBA
01/2009 - 12/2007
2UCF 101IBA
01/2008 - 02/2007
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2006 - 08/2003
2Caspase 3 (Caspase-3)IBA
05/2006 - 12/2004
2Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
09/2005 - 09/2002
2fodrinIBA
06/2005 - 12/2004
1AdenosineFDA LinkGeneric
10/2015
1methyl pyruvateIBA
12/2014
1PeroxiredoxinsIBA
08/2014
1rivastigmine (Exelon)FDA LinkGeneric
03/2014
1Serotonin (5 Hydroxytryptamine)IBA
01/2014
1Protein-Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2014
1Pentazocine (Talwin)FDA LinkGeneric
10/2013
1Piracetam (Nootropil)IBA
10/2013
1Arginine (L-Arginine)FDA Link
07/2013
1serum P-component (CIt)IBA
07/2013
1CitrullineIBA
07/2013
1Streptozocin (Streptozotocin)FDA Link
05/2013
1Protein Kinases (Protein Kinase)IBA
01/2013
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2013
1occludinIBA
01/2013
12'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2013

Therapy/Procedure

10Microspheres (Microsphere)
01/2012 - 09/2005
6Therapeutics
01/2013 - 01/2008
5Ovariectomy (Oophorectomy)
08/2011 - 12/2007
2Oral Administration
07/2013 - 07/2008