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Brigitte M Frey Selected Research

11-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)

1/2014Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11β-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines.
2/2009Prematurity is related to high placental cortisol in preeclampsia.
6/2008Age-dependent decrease in 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) activity in hypertensive patients.
11/2007Identification of polymorphisms in the human 11beta-hydroxysteroid dehydrogenase type 2 gene promoter: functional characterization and relevance for salt sensitivity.
1/2006Analbuminemic Nagase rats: blood pressure response to dietary salt challenge.
12/2005Extracellular ATP determines 11beta-hydroxysteroid dehydrogenase type 2 activity via purinergic receptors.
7/2004Glucocorticoid-mediated mineralocorticoid receptor activation and hypertension.
2/2004The 11-ketosteroid 11-ketodexamethasone is a glucocorticoid receptor agonist.
12/2003A rapid screening assay for inhibitors of 11beta-hydroxysteroid dehydrogenases (11beta-HSD): flavanone selectively inhibits 11beta-HSD1 reductase activity.
9/2003Angiotensin II regulates 11beta-hydroxysteroid dehydrogenase type 2 via AT2 receptors.
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Brigitte M Frey Research Topics

Disease

13Hypertension (High Blood Pressure)
10/2014 - 01/2002
7Pre-Eclampsia (Preeclampsia)
11/2013 - 09/2003
4Neoplasms (Cancer)
03/2015 - 02/2004
3Prostatic Neoplasms (Prostate Cancer)
03/2015 - 06/2011
3Inflammation
03/2010 - 12/2005
3Anoxia (Hypoxia)
10/2005 - 05/2003
3Edema
08/2005 - 01/2005
3Nephrotic Syndrome (Syndrome, Nephrotic)
01/2005 - 05/2002
2Ischemia
12/2005 - 05/2003
2Liver Cirrhosis (Hepatic Cirrhosis)
09/2005 - 07/2004
2Chronic Kidney Failure (Chronic Renal Failure)
10/2004 - 04/2002
1Heart Diseases (Heart Disease)
03/2014
1Critical Illness (Critically Ill)
03/2014
1Colonic Neoplasms (Colon Cancer)
01/2014
1Body Weight (Weight, Body)
01/2011
1Acute Kidney Injury (Acute Renal Failure)
03/2010
1Hyperkalemia
10/2009
1Marfan Syndrome (Marfan's Syndrome)
09/2009
1Aortic Aneurysm (Aneurysm, Aortic)
09/2009
1Aneurysm (Aneurysms)
09/2009
1Obesity
02/2009
1Birth Weight (Birth Weights)
02/2009
1Calciphylaxis
12/2008
1Kidney Diseases (Kidney Disease)
12/2008
1Acidosis
12/2008
1Ascites
06/2005
1Snake Bites (Snake Bite)
06/2005

Drug/Important Bio-Agent (IBA)

1111-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA
01/2014 - 05/2003
9SodiumIBA
01/2014 - 01/2002
8Hydrocortisone (Cortisol)FDA LinkGeneric
01/2011 - 01/2002
6AldosteroneIBA
11/2013 - 05/2002
4Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
06/2008 - 12/2003
3PotassiumIBA
07/2004 - 01/2002
2Carbon MonoxideIBA
03/2015 - 06/2005
2Androgen Receptors (Androgen Receptor)IBA
03/2015 - 06/2011
2Lactic AcidFDA LinkGeneric
01/2014 - 10/2005
2OxidoreductasesIBA
01/2014 - 12/2004
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2013 - 10/2005
2Prostate-Specific Antigen (Semenogelase)IBA
12/2011 - 06/2011
2Spironolactone (Aldactone)FDA LinkGeneric
01/2011 - 07/2004
211-beta-Hydroxysteroid Dehydrogenase Type 1IBA
02/2009 - 07/2004
2Puromycin AminonucleosideIBA
01/2005 - 05/2002
2CortisoneIBA
12/2004 - 01/2002
2Angiotensin IIIBA
07/2004 - 09/2003
211-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA
05/2003 - 05/2002
1MicroRNAs (MicroRNA)IBA
10/2014
1AndrogensIBA
03/2014
1Estrogens (Estrogen)FDA Link
03/2014
1ProgesteroneFDA LinkGeneric
03/2014
1SteroidsIBA
03/2014
1Apparent mineralocorticoid excessIBA
01/2014
1Insulin (Novolin)FDA Link
01/2014
1CCAAT-Enhancer-Binding ProteinsIBA
01/2014
1Tyrosine (L-Tyrosine)FDA Link
05/2013
1Androgen Antagonists (Antiandrogens)IBA
12/2011
1Gentian Violet (Violet, Crystal)FDA Link
12/2011
1Diphtheria ToxinIBA
06/2011
1(3- dimyristyloxypropyl)(dimethyl)(hydroxyethyl)ammoniumIBA
06/2011
1Vitamin A (Retinol)FDA LinkGeneric
03/2010
1AdrenomedullinIBA
03/2010
1Immunoglobulins (Immunoglobulin)IBA
03/2010
1Proteins (Proteins, Gene)IBA
03/2010
1Carrier Proteins (Binding Protein)IBA
03/2010
1ZincIBA
03/2010
1Glycoproteins (Glycoprotein)IBA
03/2010
1Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
03/2010
1ProteomeIBA
03/2010
1Serine Proteases (Serine Protease)IBA
03/2010
1UromodulinIBA
03/2010
1Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
03/2010
1Leucine (L-Leucine)FDA Link
03/2010
1microfibrillar proteinIBA
09/2009
1filaminsIBA
09/2009
1calponinIBA
09/2009
1VinculinIBA
09/2009
1CalpainIBA
09/2009
1CalciumIBA
12/2008
1sodium thiosulfateFDA Link
12/2008
1Adenosine Triphosphate (ATP)IBA
12/2005
1Pyruvic Acid (Pyruvate)IBA
10/2005
1EphrinsIBA
10/2005
1Small Interfering RNA (siRNA)IBA
10/2005
1Eph Family Receptors (Eph Receptors)IBA
10/2005
1OxygenIBA
10/2005
1LigandsIBA
10/2005
1Secretory Phospholipases A2IBA
08/2005
1BilirubinIBA
08/2005
1EnzymesIBA
06/2005
1Snake Venoms (Snake Venom)IBA
06/2005
1Phospholipases A2 (Phospholipase A2)IBA
06/2005
1Epithelial Sodium ChannelIBA
01/2005
1Acetylglucosaminidase (NAGase)IBA
01/2005

Therapy/Procedure

2Heterologous Transplantation (Xenotransplantation)
03/2015 - 06/2011
2Renal Dialysis (Hemodialysis)
10/2009 - 01/2002
1Castration
12/2011
1Extracorporeal Circulation
03/2010
1Cardiopulmonary Bypass (Heart-Lung Bypass)
03/2010
1Renal Replacement Therapy (Therapies, Renal Replacement)
12/2008
1Ligation
09/2005
1Traditional Medicine (Folk Remedies)
06/2005