Adenomatous Polyposis Coli

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.

Also Known As:

Familial Adenomatous Polyposis; Adenomatous Polyposis of the Colon; Adenomatous Polyposis Coli, Familial; Familial Adenomatous Polyposis Coli; Familial Adenomatous Polyposis of the Colon; Familial Intestinal Polyposis; Familial Multiple Polyposi; Familial Polyposis Coli; Familial Polyposis of the Colon; Hereditary Polyposis Coli; Polyposis, Adenomatous Intestinal; Adenomatous Intestinal Polyposes; Adenomatous Intestinal Polyposis; Adenomatous Polyposes, Familial; Adenomatous Polyposis Colus; Adenomatous Polyposis, Familial; Coli, Adenomatous Polyposis; Coli, Familial Polyposis; Coli, Hereditary Polyposis; Colus, Adenomatous Polyposis; Colus, Familial Polyposis; Colus, Hereditary Polyposis; Familial Adenomatous Polyposes; Familial Intestinal Polyposes; Familial Multiple Polyposus; Familial Polyposis Colus; Familial Polyposis Syndrome; Familial Polyposis Syndromes; Hereditary Polyposis Colus; Intestinal Polyposes, Familial; Intestinal Polyposis, Adenomatous; Intestinal Polyposis, Familial; Multiple Polyposi, Familial; Multiple Polyposus, Familial; Polyposes, Familial Adenomatous; Polyposi, Familial Multiple; Polyposis Coli, Adenomatous; Polyposis Coli, Hereditary; Polyposis Colus, Adenomatous; Polyposis Colus, Familial; Polyposis Colus, Hereditary; Polyposis, Familial Adenomatous; Polyposus, Familial Multiple; Polyposis Coli, Familial; Polyposis Syndrome, Familial

Neoplasms: 649836
- Hereditary Neoplastic Syndromes: 52
  - Adenomatous Polyposis Coli: 2205
- Neoplasms by Histologic Type: 1
  - Glandular and Epithelial Neoplasms: 332
    - Adenoma: 14662
      - Adenomatous Polyps: 571
        Adenomatous Polyposis Coli: 2205
- Neoplasms by Site: 1
  - Digestive System Neoplasms: 72
    - Gastrointestinal Neoplasms: 2147
      - Intestinal Neoplasms: 314
        Colorectal Neoplasms: 34998
        Colonic Neoplasms: 19041
        Adenomatous Polyposis Coli: 2205
        Adenomatous Polyposis Coli: 2205
Digestive System Diseases: 46
- Gastrointestinal Diseases: 1735
  - Gastrointestinal Neoplasms: 2147
    - Intestinal Neoplasms: 314
      - Colorectal Neoplasms: 34998
        Colonic Neoplasms: 19041
        Adenomatous Polyposis Coli: 2205
  - Intestinal Diseases: 773
    - Intestinal Neoplasms: 314
      - Colorectal Neoplasms: 34998
        Colonic Neoplasms: 19041
        Adenomatous Polyposis Coli: 2205
    - Colonic Diseases: 226
      - Colorectal Neoplasms: 34998
        Colonic Neoplasms: 19041
        Adenomatous Polyposis Coli: 2205
    - Intestinal Polyposis: 93
      - Adenomatous Polyposis Coli: 2205
- Digestive System Neoplasms: 72
  - Gastrointestinal Neoplasms: 2147
    - Intestinal Neoplasms: 314
      - Colorectal Neoplasms: 34998
        Colonic Neoplasms: 19041
        Adenomatous Polyposis Coli: 2205
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 668
- Inborn Genetic Diseases: 842
  - Hereditary Neoplastic Syndromes: 52
    - Adenomatous Polyposis Coli: 2205

C A Durno Selected Research

C A Durno Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure