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Nicholas S Duesbery Selected Research

anthrax toxin (anthrax lethal factor)

1/2011MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.
6/2008Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage.
4/2008The systemic administration of lethal toxin achieves a growth delay of human melanoma and neuroblastoma xenografts: assessment of receptor contribution.
3/2007LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.
1/2003Novel protein targeted therapy of metastatic melanoma.
3/2002Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase.

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Nicholas S Duesbery Research Topics

Disease

15Anthrax
01/2013 - 03/2002
14Neoplasms (Cancer)
07/2015 - 03/2002
9Melanoma (Melanoma, Malignant)
07/2015 - 03/2002
2Hemangiosarcoma (Angiosarcoma)
07/2015 - 09/2013
2Infection
01/2013 - 06/2008
1Ossifying Fibroma
07/2015
1Diabetic Retinopathy (Retinopathy, Diabetic)
01/2013
1Retinopathy of Prematurity (Retrolental Fibroplasia)
11/2011
1Anoxia (Hypoxia)
11/2011
1Retinal Neovascularization
11/2011
1Neoplasm Metastasis (Metastasis)
01/2010
1Hypotension (Low Blood Pressure)
01/2009
1Lymphopenia (Lymphocytopenia)
06/2008
1Pulmonary Edema
06/2008
1Hemorrhage
06/2008
1Shock
06/2008
1Neuroblastoma
04/2008
1Necrosis
03/2008
1Sarcoma (Soft Tissue Sarcoma)
03/2008
1Fibrosarcoma
03/2008
1Renal Cell Carcinoma (Grawitz Tumor)
01/2008
1Kaposi Sarcoma (Kaposi's Sarcoma)
10/2007
1Edema
03/2002

Drug/Important Bio-Agent (IBA)

11Protein Kinases (Protein Kinase)IBA
11/2011 - 03/2002
6Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
07/2012 - 01/2003
6anthrax toxin (anthrax lethal factor)IBA
01/2011 - 03/2002
6AntigensIBA
06/2008 - 01/2003
5Phosphotransferases (Kinase)IBA
11/2011 - 03/2002
4GelatinasesIBA
01/2010 - 03/2008
3glucuronyl glucosamine glycan sulfate (Vessel)IBA
11/2011 - 03/2008
3Proteins (Proteins, Gene)IBA
06/2008 - 01/2003
2CytokinesIBA
01/2013 - 03/2008
2Anti-Bacterial Agents (Antibiotics)IBA
01/2013 - 06/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2013 - 10/2007
2Matrix MetalloproteinasesIBA
01/2010 - 04/2009
2FurinIBA
04/2009 - 03/2008
1PD 0325901IBA
07/2015
1DNA (Deoxyribonucleic Acid)IBA
07/2015
1Transcription Factors (Transcription Factor)IBA
09/2013
1sorafenib (BAY 43-9006)FDA Link
09/2013
1OxygenIBA
11/2011
1ROPIBA
11/2011
1anaplastic Thyroid cancerIBA
01/2010
1Retinaldehyde (Retinal)IBA
01/2009
1Hemoglobins (Hemoglobin)IBA
06/2008
1edema factorIBA
06/2008
1Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)IBA
01/2008
1Clear-cell metastatic renal cell carcinomaIBA
01/2008
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
10/2007
1GTP-Binding Proteins (G-Protein)IBA
10/2007
1U 0126 (UO 126)IBA
09/2005
1anthrax toxin receptorsIBA
09/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2003
1Cutaneous anthraxIBA
03/2002
1Melanins (Melanin)IBA
03/2002

Therapy/Procedure

9Heterologous Transplantation (Xenotransplantation)
01/2015 - 03/2002
2Drug Therapy (Chemotherapy)
07/2012 - 01/2003
1Microbubbles
03/2008
1Immunotherapy
01/2003