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Mary C Dinauer Selected Research

4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)

3/2011Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease.
11/2010p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.
10/2010Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner.
12/2008Mutational analysis reveals distinct features of the Nox4-p22 phox complex.
6/2007Granulocyte colony-stimulating factor prior to nonmyeloablative irradiation decreases murine host hematopoietic stem cell function and increases engraftment of donor marrow cells.
7/2006The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells.
3/2005Unusual polyclonal anti-gp91 peptide antibody interactions with X-linked chronic granulomatous disease-derived human neutrophils are not from compensatory expression of Nox proteins 1, 3, or 4.
5/2003Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker.

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Mary C Dinauer Research Topics

Disease

18Chronic Granulomatous Disease
01/2014 - 03/2002
7Inflammation
12/2015 - 10/2005
7Infection
11/2013 - 06/2002
2Pneumonia (Pneumonitis)
03/2015 - 02/2008
2Neoplasms (Cancer)
12/2007 - 07/2006
1Peritonitis
04/2013
1Bacterial Pneumonia
05/2011
1Leukemia
10/2010
1Neurofibromatosis 1 (Neurofibromatosis Type I)
03/2010
1Neointima
03/2010
1Vascular Diseases (Vascular Disease)
03/2010
1Colitis
10/2009
1Ischemia
03/2009
1Cardiovascular Diseases (Cardiovascular Disease)
12/2008
1Lung Neoplasms (Lung Cancer)
12/2008
1Lung Injury
02/2008
1Vascular System Injuries
02/2008
1Bacterial Infections (Bacterial Infection)
12/2007
1Hematologic Diseases (Blood Diseases)
06/2007
1Foreign Bodies (Foreign Body)
07/2006
1Fibrosarcoma
07/2006
1Neoplasm Metastasis (Metastasis)
07/2006
1Melanoma (Melanoma, Malignant)
07/2006
1Granuloma
01/2003
1Sepsis (Septicemia)
04/2002

Drug/Important Bio-Agent (IBA)

12NADPH Oxidase (NAD(P)H oxidase)IBA
12/2015 - 03/2002
84- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
03/2011 - 05/2003
5OxidoreductasesIBA
04/2013 - 06/2002
4Superoxides (Superoxide)IBA
10/2009 - 08/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
12/2015 - 07/2006
3NADP (NADPH)IBA
12/2015 - 06/2002
3InterferonsIBA
03/2015 - 05/2011
3Peroxidase (Myeloperoxidase)IBA
01/2014 - 06/2002
2InterleukinsIBA
04/2013 - 01/2005
2CytokinesIBA
04/2013 - 03/2010
2neutrophil cytosol factor 40KIBA
10/2012 - 10/2009
2Proteins (Proteins, Gene)IBA
11/2010 - 03/2005
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
12/2015
1Interleukin-1 (Interleukin 1)IBA
12/2015
1Interleukin-13IBA
04/2013
1NAD (NADH)IBA
04/2013
1Interleukin-4 (Interleukin 4)IBA
04/2013
1Messenger RNA (mRNA)IBA
05/2011
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2010
1Neurofibromin 1 (Neurofibromin)IBA
03/2010
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
03/2010
1Insulin (Novolin)FDA Link
12/2008
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
12/2008
1Histidine (L-Histidine)FDA Link
12/2008
1Tyrosine (L-Tyrosine)FDA Link
12/2008
1Caveolin 1IBA
02/2008
1Monomeric GTP-Binding ProteinsIBA
12/2007
1thymosin beta(4)IBA
07/2006
1GelatinIBA
07/2006
1Carbon MonoxideIBA
07/2006
1CatalaseIBA
08/2005
1Immunoglobulin G (IgG)IBA
03/2005
1AntibodiesIBA
03/2005
1Interferon-gamma (Interferon, gamma)IBA
01/2005
1Fluorouracil (Carac)FDA LinkGeneric
12/2004
1Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA
05/2003
1Oxidants (Oxidizing Agents)IBA
01/2003
1EnzymesIBA
06/2002

Therapy/Procedure

1Hematopoietic Stem Cell Transplantation
03/2010
1Ligation
03/2009
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
06/2007
1Transplantation (Transplant Recipients)
06/2007