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Jorge De Alba Selected Research

Purinones

10/2019Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases.

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Jorge De Alba Research Topics

Disease

8Asthma (Bronchial Asthma)
10/2019 - 10/2005
6Inflammation (Inflammations)
10/2019 - 10/2005
4Chronic Obstructive Pulmonary Disease (COPD)
10/2019 - 08/2012
2Respiratory Tract Diseases (Respiratory Tract Disease)
10/2019 - 01/2019
2Hypersensitivity (Allergy)
12/2015 - 01/2006
2Eosinophilia
09/2008 - 10/2005
1Lung Diseases (Lung Disease)
12/2015
1Respiratory Hypersensitivity
12/2015
1Chronic Cough
12/2015
1Cough
12/2015
1Fibrosis (Cirrhosis)
12/2015
1Disease Progression
12/2015
1type 2C Congenital disorder of glycosylation
09/2015
1Bronchial Spasm
08/2012
1Arthralgia (Joint Pain)
08/2006
1Emphysema
08/2006
1Neuralgia (Stump Neuralgia)
01/2006
1Pain (Aches)
01/2006
1Pneumonia (Pneumonitis)
10/2005

Drug/Important Bio-Agent (IBA)

4CytokinesIBA
10/2019 - 10/2005
3Janus Kinase InhibitorsIBA
10/2019 - 01/2017
2LipopolysaccharidesIBA
10/2019 - 01/2017
2AllergensIBA
01/2019 - 03/2015
25- (2- ((6- (2,2- difluoro- 2- phenylethoxy)hexyl)amino)- 1- hydroxyethyl)- 8- hydroxyquinolin- 2(1H)- oneIBA
01/2016 - 08/2012
1PurinonesIBA
10/2019
1Janus KinasesIBA
10/2019
1Muscarinic AntagonistsIBA
01/2019
1AZD-8871IBA
01/2019
1Bronchodilator Agents (Bronchodilators)IBA
01/2019
1OvalbuminIBA
01/2019
1tofacitinibIBA
01/2017
1Double-Stranded RNA (RNA, Double Stranded)IBA
12/2015
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
12/2015
1Citric Acid (Citrate)FDA LinkGeneric
12/2015
1Brain-Derived Neurotrophic Factor (BDNF)IBA
12/2015
1Calcium Release Activated Calcium ChannelsIBA
12/2015
1Adrenal Cortex Hormones (Corticosteroids)IBA
12/2015
1ChemokinesIBA
12/2015
1Interleukin-13IBA
12/2015
1Antitussive Agents (Antitussives)FDA Link
12/2015
1Bleomycin (Blenoxane)FDA LinkGeneric
12/2015
1Capsaicin (Zostrix)FDA Link
12/2015
1Immunoglobulins (Immunoglobulin)IBA
12/2015
1Interleukin-2 (IL2)IBA
12/2015
1Interleukin-7 (Interleukin 7)IBA
12/2015
1Poly I-CIBA
12/2015
11- (2- (2,5- diazabicyclo(2.2.1)hept- 2- yl)pyridin- 4- yl)- N- pyrazin- 2- yl- 1H- indazol- 3- amineIBA
09/2015
17-azaindole dimerIBA
03/2015
1indacaterolIBA
08/2012
1Salmeterol Xinafoate (Serevent)FDA Link
08/2012
1Formoterol Fumarate (Oxis)FDA Link
08/2012
1Liver X ReceptorsIBA
09/2008
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
09/2008
1LigandsIBA
09/2008
1Biomarkers (Surrogate Marker)IBA
09/2008
1GW 3965IBA
09/2008
1Pancreatic Elastase (Elastase)IBA
08/2006
1Matrix Metalloproteinase InhibitorsIBA
08/2006
1Matrix Metalloproteinases (MMPs)IBA
08/2006
1Analgesics (Analgesic Drugs)IBA
01/2006
1Nitric Oxide Synthase (NO Synthase)IBA
01/2006
1Protein Isoforms (Isoforms)IBA
01/2006
1GW 274150IBA
01/2006
1AntigensIBA
10/2005
1NF-kappa B (NF-kB)IBA
10/2005
1SteroidsIBA
10/2005
1Proteins (Proteins, Gene)FDA Link
10/2005
1Budesonide (Pulmicort)FDA LinkGeneric
10/2005

Therapy/Procedure

3Therapeutics
01/2016 - 08/2006