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Jorge Cortes Selected Research

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

7/2015Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia.
6/2015A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.
5/2015Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
4/2015The role of ponatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia.
3/2015Prognostic factors for outcome in patients with refractory and relapsed acute lymphocytic leukemia treated with inotuzumab ozogamicin, a CD22 monoclonal antibody.
2/2015Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia.
6/2014Phase I and extension study of clofarabine plus cyclophosphamide in patients with relapsed/refractory acute lymphoblastic leukemia.
3/2014Phase II trial of hyper CVAD and dasatinib in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia or blast phase chronic myeloid leukemia.
8/2013Results of inotuzumab ozogamicin, a CD22 monoclonal antibody, in refractory and relapsed acute lymphocytic leukemia.
11/2012Dasatinib for the treatment of Philadelphia chromosome-positive leukemias.
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Jorge Cortes Research Topics

Disease

219BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2015 - 03/2002
82Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
09/2015 - 08/2002
56Philadelphia Chromosome
11/2015 - 04/2002
55Leukemia
08/2015 - 03/2002
55Myelodysplastic Syndromes (Myelodysplastic Syndrome)
04/2015 - 07/2002
44Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
07/2015 - 03/2002
37Neoplasms (Cancer)
07/2015 - 10/2002
24Primary Myelofibrosis (Myelosclerosis)
08/2015 - 03/2003
23Blast Crisis (Blast Phase)
10/2015 - 05/2002
19Hematologic Neoplasms (Hematological Malignancy)
09/2015 - 10/2002
17B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
05/2015 - 04/2003
14Acute Promyelocytic Leukemia
05/2015 - 05/2003
12Infection
11/2015 - 01/2003
12Chromosome Aberrations (Chromosome Abnormalities)
08/2012 - 05/2002
11Myeloid Leukemia (Leukemia, Myelocytic)
09/2014 - 04/2006
11Anemia
09/2014 - 04/2002
9Thrombocytopenia (Thrombopenia)
01/2014 - 06/2004
9Polycythemia Vera
08/2013 - 06/2003
9Myeloproliferative Disorders (Myeloproliferative Disorder)
02/2008 - 10/2002
8Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
04/2014 - 06/2003
7Essential Thrombocythemia
08/2013 - 01/2003
6Neutropenia
09/2015 - 06/2004
6Nausea
07/2015 - 10/2002
6Hypereosinophilic Syndrome (Loeffler Endocarditis)
06/2013 - 09/2002
6Residual Neoplasm
10/2012 - 01/2003
5Lymphoma (Lymphomas)
05/2015 - 12/2003
5Splenomegaly
10/2014 - 06/2010
5Systemic Mastocytosis
09/2013 - 05/2004
4Exanthema (Rash)
11/2015 - 06/2009
4Diarrhea
05/2012 - 08/2002
4Multiple Myeloma
08/2011 - 03/2003
4Fibrosis (Cirrhosis)
10/2009 - 07/2004
3Pneumonia (Pneumonitis)
09/2015 - 01/2003
3Sepsis (Septicemia)
09/2015 - 11/2004
3Mucositis
06/2015 - 08/2002
3Hemorrhage
04/2015 - 06/2009
3Refractory Anemia with Excess of Blasts (RAEM)
10/2014 - 03/2003
3Fever (Fevers)
08/2013 - 01/2003
3Disease Progression
10/2012 - 11/2006
3Drug Toxicity (Drug Safety)
06/2011 - 10/2010
3Leukocytosis (Pleocytosis)
12/2010 - 12/2003

Drug/Important Bio-Agent (IBA)

167imatinib (Gleevec)FDA Link
10/2015 - 05/2002
98Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2015 - 09/2003
38Cytarabine (Cytosar-U)FDA LinkGeneric
09/2015 - 03/2002
36Phosphotransferases (Kinase)IBA
03/2015 - 12/2003
34dasatinib (BMS 354825)FDA Link
04/2015 - 06/2006
294- methyl- N- (3- (4- methylimidazol- 1- yl)- 5- (trifluoromethyl)phenyl)- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)benzamide (nilotinib)FDA Link
11/2014 - 07/2005
15decitabine (5-aza-2'-deoxycytidine)FDA Link
07/2015 - 08/2003
14Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2015 - 03/2002
14InterferonsIBA
10/2013 - 06/2003
14Interferon-alpha (Interferon Alfa)FDA Link
06/2012 - 04/2002
13Bcr-Abl tyrosine kinaseIBA
10/2015 - 06/2004
12Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2015 - 05/2003
11rituximab (Mabthera)FDA Link
02/2015 - 04/2003
11fludarabineIBA
11/2014 - 03/2003
10clofarabine (Clolar)FDA Link
07/2015 - 03/2003
10homoharringtonineIBA
01/2015 - 04/2002
9Vincristine (Oncovin)FDA LinkGeneric
05/2015 - 03/2002
9Dexamethasone (Maxidex)FDA LinkGeneric
05/2015 - 03/2002
8Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
05/2015 - 08/2002
7arsenic trioxide (Trisenox)FDA Link
05/2015 - 05/2003
7Hemoglobins (Hemoglobin)IBA
10/2014 - 04/2002
7TransferasesIBA
11/2007 - 03/2003
6Proteins (Proteins, Gene)IBA
10/2015 - 02/2007
6INCB018424IBA
08/2015 - 11/2011
6lenalidomide (CC 5013)FDA Link
08/2015 - 08/2006
6Doxorubicin (Adriamycin)FDA LinkGeneric
05/2015 - 03/2002
6Azacitidine (5 Azacytidine)FDA Link
04/2015 - 10/2007
6Histone Deacetylase InhibitorsIBA
09/2012 - 08/2006
6tipifarnib (R115777)IBA
03/2011 - 10/2002
6gemtuzumab (gemtuzumab ozogamicin)FDA Link
02/2009 - 12/2002
5Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
02/2015 - 05/2005
5sorafenib (BAY 43-9006)FDA Link
06/2013 - 02/2008
5alemtuzumab (Campath)FDA Link
06/2013 - 12/2003
4AntigensIBA
09/2014 - 09/2013
4fms-Like Tyrosine Kinase 3IBA
07/2014 - 02/2008
4Farnesyltranstransferase (Farnesyltransferase)IBA
03/2011 - 10/2002
4Itraconazole (Sporanox)FDA LinkGeneric
01/2011 - 01/2003
4Daunorubicin (Cerubidine)FDA LinkGeneric
11/2010 - 03/2003
4Reticulin (Reticular Fiber)IBA
10/2009 - 07/2004
4Topotecan (Hycamtin)FDA LinkGeneric
10/2006 - 12/2002
3Methotrexate (Mexate)FDA LinkGeneric
02/2015 - 03/2002
3BilirubinIBA
02/2015 - 04/2012
3Tyrosine (L-Tyrosine)FDA Link
02/2015 - 06/2010
3IronIBA
10/2014 - 07/2006
3Prednisone (Sone)FDA LinkGeneric
09/2014 - 10/2009
3Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
01/2013 - 07/2002
3bosutinibIBA
11/2012 - 08/2008
3Proteasome Endopeptidase Complex (Proteasome)IBA
08/2011 - 05/2004
3Thalidomide (Thalomid)FDA Link
07/2011 - 03/2003

Therapy/Procedure

46Drug Therapy (Chemotherapy)
11/2015 - 03/2002
13Stem Cell Transplantation
08/2015 - 07/2003
11Salvage Therapy
09/2015 - 04/2003
11Transplants (Transplant)
08/2015 - 08/2006
7Hematopoietic Stem Cell Transplantation
08/2015 - 08/2004
5Cell Transplantation
09/2014 - 09/2012
4Homologous Transplantation (Allograft)
03/2015 - 08/2004
4Transplantation (Transplant Recipients)
03/2014 - 10/2007
3Heterologous Transplantation (Xenotransplantation)
03/2014 - 10/2002
3Aftercare (After-Treatment)
02/2011 - 12/2003